Results 41 to 50 of about 2,854 (146)

Engineering Gossypol‐Free Cottonseeds for Future Global Food Security and Agricultural Sustainability

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
This study depicting the role of transcriptomics, RNA interference (RNAi), and CRISPR/Cas9 technologies in the breeding of glandless cottonseed and glanded cotton tissues. This approach demonstrates the potential of cotton as a dual‐purpose crop, serving both the fiber industry and as a sustainable food and feed source.
Teame Gereziher Mehari   +9 more
wiley   +1 more source

Metabolic engineering of Ashbya gossypii for limonene production from xylose

open access: yesBiotechnology for Biofuels and Bioproducts, 2022
Background Limonene is a cyclic monoterpene that has applications in the food, cosmetic, and pharmaceutical industries. The industrial production of limonene and its derivatives through plant extraction presents important drawbacks such as seasonal and ...
Gloria Muñoz-Fernández   +3 more
doaj   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda   +12 more
wiley   +1 more source

Light Regulation of Chlorophyll and Glycoalkaloid Biosynthesis During Tuber Greening of Potato S. tuberosum

open access: yesFrontiers in Plant Science, 2020
Potato, S. tuberosum, is one of the most important global crops, but has high levels of waste due to tuber greening under light, which is associated with the accumulation of neurotoxic glycoalkaloids.
Haruko Okamoto   +11 more
doaj   +1 more source

Cytomegalic parvalbumin neurons in fetal cases of hemimegalencephaly

open access: yesEpilepsia, Volume 66, Issue 6, Page 2099-2109, June 2025.
Abstract Objective Mutations in genes of the mTOR pathway have been identified as a major cause of hemimegalencephaly (HMG), focal cortical dysplasia type II, and tuberous sclerosis, cortical malformations associated with epilepsy. These conditions are characterized at the cellular level by increased size of pyramidal neurons that grow with dysmorphic ...
Antoinette‐Bernabe Gelot   +8 more
wiley   +1 more source

Hmg4, a new member of the Hmg1/2 gene family

open access: yes, 1998
High mobility group (HMG) proteins are abundant components of mammalian nuclei and fall into three families. The members of one such family, HMG1 and HMG2, are ubiquitously expressed and facilitate the formation of nucleoprotein complexes where the DNA ...
M. Beltrame   +3 more
core   +1 more source

Structural and Kinetic Studies of a Cisplatin-modified DNA Icosamer Binding to HMG1 Domain B* [PDF]

open access: yes, 1999
The high mobility group (HMG) domain is a DNA-binding motif found in the non-histone chromosomal proteins, HMG1 and HMG2, and some transcription factors. Experimental evidence has demonstrated that HMG-domain proteins can play a role in sensitizing cells
Jamieson, Elizabeth R   +4 more
core   +1 more source

Purification of the HMG1 protein and investigation of its interactions with diepoxide cross-linked DNA [PDF]

open access: yes, 2002
HMG1 is a nonhistone chromosomal protein that binds preferentially to some types of globally modified DNA. HMG1 has been implicated in the cellular response to the anti-cancer agent cisplatin, functioning to block excision repair of specific distorted ...
Pageau, Gayle
core   +1 more source

Characterization and functional reconstruction of a highly productive germacrene A synthase from Liriodendron chinense

open access: yesPlant Biotechnology Journal, Volume 23, Issue 6, Page 1927-1937, June 2025.
Germacrene A Synthase (LcTPS3) from Liriodendron was characterized. The biosynthesis of germacrene A was achieved in a yeast chassis, and the catalytic mechanism of LcTPS3 was further elucidated. Summary Plants produce a large array of natural products which play important roles in flavours, fragrances and medicines.
Weijia Cheng   +12 more
wiley   +1 more source

The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13

open access: yes, 1996
The human genome contains a large number of sequences related to the cDNA for High Mobility Group 1 protein (HMG1), which so far has hampered the cloning and mapping of the active HMG1 gene.
M. E. Bianchi   +7 more
core   +1 more source

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