Results 41 to 50 of about 2,248 (159)
Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. [PDF]
PLoS ONE, 2009 In humans, defects in lipid metabolism are associated with a number of severe diseases such as atherosclerosis, obesity and type II diabetes. Hypercholesterolemia is a primary risk factor for coronary artery disease, the major cause of premature deaths ...
Agata Leszczynska +9 more
doaj +1 more source
Difference in HMG1-induced DNA Bending Among Microsatellites [PDF]
DNA Research, 1997 Sequence-dependency of high-mobility group protein (HMG) 1-induced DNA bending is examined for microsatellites using a circularization assay which can measure the extent of bending. Fragments of 133 bp containing (GGA/TCC)11 in the middle showed greater bending than those harboring (GAA/TTC)11 and (GT/AC)17 repeats, and fragments possessing (GA/TC)17 ...
K, Takayanagi, Y, Mishima, R, Kominami
openaire +2 more sources
Changes in the nuclear proteome of developing wheat (Triticum aestivum L.) grain
Frontiers in Plant Science, 2015 Wheat grain end-use value is determined by complex molecular interactions that occur during grain development, including those in the cell nucleus. However our knowledge of how the nuclear proteome changes during grain development is limited.
Titouan eBonnot +10 more
doaj +1 more source
Metabolic engineering of Ashbya gossypii for limonene production from xylose
Biotechnology for Biofuels and Bioproducts, 2022 Background Limonene is a cyclic monoterpene that has applications in the food, cosmetic, and pharmaceutical industries. The industrial production of limonene and its derivatives through plant extraction presents important drawbacks such as seasonal and ...
Gloria Muñoz-Fernández +3 more
doaj +1 more source
Food Frontiers, Volume 7, Issue 1, January 2026.This study depicting the role of transcriptomics, RNA interference (RNAi), and CRISPR/Cas9 technologies in the breeding of glandless cottonseed and glanded cotton tissues. This approach demonstrates the potential of cotton as a dual‐purpose crop, serving both the fiber industry and as a sustainable food and feed source.
Teame Gereziher Mehari +9 more
wiley +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, Volume 12, Issue 37, October 6, 2025.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Hmg1 mutations in Aspergillus fumigatus and their contribution to triazole susceptibility
Medical Mycology, 2021 Abstract Triazole-resistant Aspergillus fumigatus is a global health concern. In general, each triazole resistance pattern caused by the specified amino acid substitution of Cyp51A has a typical pattern depending on the mutation site. We evaluated the contribution of both Cyp51A and Hmg1 mutations to
Teppei Arai +6 more
openaire +2 more sources
Cytomegalic parvalbumin neurons in fetal cases of hemimegalencephaly
Epilepsia, Volume 66, Issue 6, Page 2099-2109, June 2025.Abstract Objective Mutations in genes of the mTOR pathway have been identified as a major cause of hemimegalencephaly (HMG), focal cortical dysplasia type II, and tuberous sclerosis, cortical malformations associated with epilepsy. These conditions are characterized at the cellular level by increased size of pyramidal neurons that grow with dysmorphic ...
Antoinette‐Bernabe Gelot +8 more
wiley +1 more source
Frontiers in Plant Science, 2020 Potato, S. tuberosum, is one of the most important global crops, but has high levels of waste due to tuber greening under light, which is associated with the accumulation of neurotoxic glycoalkaloids.
Haruko Okamoto +11 more
doaj +1 more source
Plant Biotechnology Journal, Volume 23, Issue 6, Page 1927-1937, June 2025.Germacrene A Synthase (LcTPS3) from Liriodendron was characterized. The biosynthesis of germacrene A was achieved in a yeast chassis, and the catalytic mechanism of LcTPS3 was further elucidated. Summary Plants produce a large array of natural products which play important roles in flavours, fragrances and medicines.
Weijia Cheng +12 more
wiley +1 more source