Cellular vimentin regulates the infectivity of Newcastle disease virus through targeting of the HN protein [PDF]
Veterinary Research, 2023 The haemagglutinin-neuraminidase (HN) protein plays a crucial role in the infectivity and virulence of Newcastle disease virus (NDV). In a previous study, the mutant HN protein was identified as a crucial virulence factor for the velogenic variant NDV ...
Xiaolong Lu +12 more
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Residues 315 and 369 in HN Protein Contribute to the Thermostability of Newcastle Disease Virus [PDF]
Frontiers in Microbiology, 2020 Thermostable Newcastle disease virus (NDV) vaccines have been widely used in areas where a “cold-chain” is not reliable. However, the molecular mechanism of NDV thermostability remains poorly understood.
Baoyang Ruan +7 more
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Identification of a new amino acid mutation in the HN protein of NDV involved in pathogenicity [PDF]
Veterinary Research, 2021 The fusion (F) and haemagglutinin-neuraminidase (HN) proteins of Newcastle disease virus (NDV) are viral entry proteins and are recognized as the major virulence determinants. Previously, a lentogenic NDV virus (CE16) was derived from a mesogenic strain (
Xi Chen +8 more
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The Hemagglutinin-Neuraminidase (HN) Head Domain and the Fusion (F) Protein Stalk Domain of the Parainfluenza Viruses Affect the Specificity of the HN-F Interaction [PDF]
Frontiers in Microbiology, 2018 Membrane fusion by the parainfluenza viruses is induced by virus-specific functional interaction between the attachment protein (HN) and the fusion (F) protein.
Masato Tsurudome +4 more
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Roles of the highly conserved amino acids in the second receptor binding site of the Newcastle disease virus HN protein [PDF]
Virology Journal, 2019 Background The paramyxovirus haemagglutinin-neuraminidase (HN) is a multifunctional protein that is responsible for attachment to receptors, removal of receptors from infected cells to prevent viral self-aggregation (neuraminidase, NA) and fusion ...
Yaqing Liu +7 more
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A 176 amino acid polypeptide derived from the mumps virus HN ectodomain shows immunological and biological properties similar to the HN protein [PDF]
Virology Journal, 2010 Background The hemagglutinin-neuraminidase (HN) protein is the major antigenic determinant of the Mumps virus (MuV) and plays an important role in the viral infectious cycle through its hemagglutination/hemadsorption (HA/HD) and neuraminidase (NA ...
Herrera Emma +5 more
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Contribution of HN protein length diversity to Newcastle disease virus virulence, replication and biological activities. [PDF]
Sci Rep, 2016 AbstractTo evaluate the contribution of length diversity in the hemagglutinin-neuraminidase (HN) protein to the pathogenicity, replication and biological characteristics of Newcastle disease virus (NDV), we used reverse genetics to generate a series of recombinant NDVs containing truncated or extended HN proteins based on an infectious clone of ...
Jin J, Zhao J, Ren Y, Zhong Q, Zhang G.
europepmc +4 more sources
Nucleotide sequence characterization, amino acid variations and 3D structural analysis of HN protein of the NDV VIId genotype [PDF]
Veterinary Medicine and ScienceBackground Haemagglutinin–neuraminidase (HN) is one of the membrane proteins of Newcastle disease virus (NDV) that plays a significant role during host viral infection.
Amin Tavassoli +2 more
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The Impact of Coffee, Matcha, Protein Drinks, and Water Storage on the Microhardness and Color Stability of a Nano-Ceramic Hybrid Composite CAD/CAM Blank [PDF]
Journal of Functional BiomaterialsThis study aimed to evaluate the effect of popular beverages, coffee, matcha, and protein isolate, on the microhardness and color stability of feldspar glass ceramic (VB) and nano-ceramic hybrid composite (GD) CAD/CAM materials.
Hanin E. Yeslam +3 more
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Viruses, 2022 As a multifunctional protein, the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is involved in various biological functions.
Xiaolong Lu +10 more
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