Results 61 to 70 of about 32,408 (167)

Advances in immunotherapy for HNSCC

Serican Journal of Medicine
Head and Neck Squamous Cell Carcinoma (HNSCC) is a cancer that originates in the mucosal surfaces of the head and neck, including the mouth, throat, and larynx. Immunotherapy has emerged as a promising treatment for HNSCC, especially for patients whose cancers are resistant to traditional therapies such as surgery, radiation, and chemotherapy.
Lin Dong, Haixia Xu, Xionghao Pang, Yiqian Liu, Meixiang Li   +4 more
openaire   +1 more source

Inhibition of GSK3α/β impairs the progression of HNSCC [PDF]

Oncotarget, 2018
Head and neck squamous cell cancer (HNSCC) is one of the most common tumors worldwide and there is an enormous need for innovative therapy approaches. Several recent studies suggest tumor entity specific roles of glycogen synthase kinase 3 (GSK3) in different human cancers, acting as tumor suppressor or as tumor promoter.
Schulz, Lisa, Pries, Ralph, Lanka, Aruna Sree, Drenckhan, Maren, Rades, Dirk, Wollenberg, Barbara   +5 more
openaire   +2 more sources

Comprehensive analysis of mitophagy in HPV-related head and neck squamous cell carcinoma

Scientific Reports, 2023
Head and neck squamous cell carcinoma (HNSCC) is a common tumour type in otorhinolaryngology, and its occurrence is related to long-term exposure to tobacco and alcohol.
Li Yanan, Liang Hui, Cheng Zhuo, Ding Longqing, Sun Ran   +4 more
doaj   +1 more source

CBX3 is a Prognostic Biomarker Correlated with ATR Activation and Immune Infiltration in Head and Neck Squamous Cell Carcinoma

International Journal of General Medicine, 2022
Xu Zhang,1– 3,* Wenkai Zhou,1– 3,* Yu Zhang,1– 3 Zheqi Liu1– 3 1Department of Oral and Maxillofacial & Head and Neck Oncology, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai ...
Zhang X, Zhou W, Zhang Y, Liu Z
doaj  

GDNF secreted by nerves enhances PD-L1 expression via JAK2-STAT1 signaling activation in HNSCC

OncoImmunology, 2017
Programmed death ligand 1 (PD-L1) functions as a key immune inhibitory factor by binding with its receptor, programmed death 1 (PD-1), to induce immune cell dysfunction and escape of the immune system.
Chengzhong Lin, Wei Cao, Zhenhu Ren, Yu Tang, Chunye Zhang, Rong Yang, Yiming Chen, Zheqi Liu, Canbang Peng, Lizhen Wang, Xu Wang, Tong Ji   +11 more
doaj   +1 more source

Molecular Patterns and Biology of HPV-Associated HNSCC

, 2016
Head and neck cancer is the sixth most common cancer worldwide. The large majority are squamous cell carcinomas (HNSCC) that develop in the mucosal linings of the upper aerodigestive tract. These tumors develop either by exogenous carcinogen exposure (smoking, alcohol drinking) or by human papillomavirus (HPV) infection, particularly those in the ...
Brakenhoff, Ruud H., Wagner, Steffen, Klussmann, Jens P.   +2 more
openaire   +4 more sources

Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways

Cancer Cell International, 2019
Background Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and human papillomavirus (HPV) has been increasingly recognized as a pathogenic factor for the initiation and development of HNSCC.
Yu Jin, Yuexiu Li, Xin Wang, Ya Yang
doaj   +1 more source

HNSCC: Lymphknoten mit Vorhersagekraft [PDF]

HNO Nachrichten, 2016
Die Analyse des Lymphknotenbefalls bei Patienten mit einem Plattenepithelkarzinom des Kopf- und Halsbereiches (HNSCC) gilt als wichtiger prognostischer Faktor, der die Therapieentscheidung mitbeeinflusst. Nun wurde untersucht, ob der Grad des Lymphknotenbefalls auch das Uberleben vorhersagt.
openaire   +2 more sources

Characterization of ANXA1 in chemotherapy resistance of head and neck squamous cell carcinoma: insights from artificial intelligence and integrative bioinformatics analysis

Frontiers in Cell and Developmental Biology
BackgroundHead and neck squamous cell carcinoma (HNSCC) exhibits intensive chemoresistance (CR), leading to frequent recurrence and poor prognosis; however, actionable biomarkers and therapeutic options remain limited.MethodsBy utilizing bulk profiles of
Ling Zheng, Ling Zheng, Haiyan Yang, Haiyan Yang, Yan Cheng, Binxue Xia, Honghui Liu, Hong Xiong   +7 more
doaj   +1 more source

Tumor suppressor ACER1 correlates with prognosis and Immune Infiltration in head and neck squamous cell carcinoma

Scientific Reports
Head and neck squamous cell carcinoma (HNSCC) is notorious for poor prognoses, and effective biomarkers are urgently needed for early diagnosis of HNSCC patients.
Zhixin Liu, Xiaoqi Yang, Shuai Chen, Wenming Jia, Ye Qian, Minfa Zhang, Tianhe Fang, Heng Liu, Hui Yang   +8 more
doaj   +1 more source