Results 41 to 50 of about 48,974 (212)

Research Progress of Ferroptosis in Head and Neck Squamous Cell Carcinoma

open access: yesZhongliu Fangzhi Yanjiu, 2022
Squamous cell carcinoma of the head and neck (HNSCC) is one of the cancers with the highest incidence rate in the world. Due to the presence of postoperative recurrence and resistance to some chemotherapeutics after the surgery, the prognosis of advanced
XIE Zhanghong, HUA Qingquan
doaj   +1 more source

Demographic and clinical characteristics of HNSCC patients.

open access: yes, 2020
Demographic and clinical characteristics of HNSCC patients.
Rushdi S. Fadhil (8616717)   +4 more
core   +1 more source

Immunotherapeutic Strategies for Head and Neck Squamous Cell Carcinoma (HNSCC): Current Perspectives and Future Prospects

open access: yes, 2022
Neoantigens are abnormal proteins produced by genetic mutations in somatic cells. Because tumour neoantigens are expressed only in tumour cells and have immunogenicity, they may represent specific targets for precision immunotherapy.
Zhang, Anqi   +7 more
core   +1 more source

Exosomal microRNAs Targeting TP53 Gene as Promising Prognostic Markers for Head and Neck Squamous Cell Carcinoma

open access: yesGlobal Medical Genetics, 2022
Statement of Problem MicroRNAs are small non-coding RNAs that regulate an array of functions by targeting crucial genes. A significant dysregulation in the TP53 profile has been observed in the head and neck squamous cell carcinoma (HNSCC) patients ...
Vijayashree Priyadharsini Jayaseelan   +1 more
doaj   +1 more source

Associations of GWAS-Identified Risk Loci with Progression, Efficacy and Toxicity of Radiotherapy of Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy

open access: yesPharmacogenomics and Personalized Medicine, 2021
Qinghuan Li,1,* Yi Liang,1,* Zeng Liu,2 Chuanyun Yu1 1Oncology Radiotherapy Center, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, 441021, People’s Republic of China; 2Department of ...
Li Q, Liang Y, Liu Z, Yu C
doaj  

Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma

open access: yesBiomolecules, 2019
STAT3 is a latent transcription factor that plays a vital role in the transmission of extracellular signal from receptors to the nucleus. It has been regarded as a master transcription factor due to its role in the regulation of a broad spectrum of genes,
Jong Hyun Lee   +7 more
doaj   +1 more source

Depth of tumor infiltration as a prognosticator in pT1-2 cN0 oral squamous cell carcinoma thereby need for elective neck dissection – A meta-analysis

open access: yesCancer Research, Statistics, and Treatment, 2019
Aim: The aim of the study is to identify the cutoff value for depth of infiltration that predicts the risk of lymph node metastasis in the neck in surgically treated patients affected by pT1/pT2 cN0 oral squamous cell carcinoma (OSCC).
Mohammad Akheel   +4 more
doaj   +1 more source

PRF1 is a prognostic marker and correlated with immune infiltration in head and neck squamous cell carcinoma

open access: yesTranslational Oncology, 2021
Purpose: Head and neck squamous cell carcinoma (HNSCC) is a highly invasive malignancy with poor survival. Perforin (PRF1) plays essential roles in host immunity.
Cui Fan   +6 more
doaj   +1 more source

Mutation rates of FOM HNSCC.

open access: yes, 2014
(A) Numbers of missense and nonsense mutations were compared between patients with FOM or non-FOM HNSCC. (B) Mutation rates were compared between patients with FOM or non-FOM HNSCC.
Jennifer R. Grandis (505756)   +3 more
core   +1 more source

Machine learning with the TCGA-HNSC dataset: improving usability by addressing inconsistency, sparsity, and high-dimensionality

open access: yesBMC Bioinformatics, 2019
Background In the era of precision oncology and publicly available datasets, the amount of information available for each patient case has dramatically increased.
Michael C. Rendleman   +7 more
doaj   +1 more source

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