Results 21 to 30 of about 47,439 (299)
Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma. [PDF]
Animal Model Exp MedA zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Chen L +11 more
europepmc +2 more sources
Cancer Research, Statistics, and Treatment, 2021 Background: The sarcomatoid variant of squamous cell carcinoma (SCC) is an uncommon variant of head-and-neck cancer with a clinically aggressive course and poor outcomes. The data on the clinical presentation and pattern of treatment received by patients
Adhara Chakraborthy +3 more
doaj +1 more source
Epithelial-Mesenchymal Transition and Inflammation in Head and Neck Squamous Cell Carcinoma [PDF]
Journal of Sciences, Islamic Republic of Iran, 2020 Head and neck squamous cell carcinoma (HNSCC) represents a large majority of cancers arising from the head and neck, especially the oral cavity. Despite advances in therapy, the five-year survival rate remains low due to the number of patients presenting
Habib Sadeghi Rad +4 more
doaj +1 more source
The role of CD44 in HNSCC [PDF]
Cancer Biology & Therapy, 2007 Commentary to:Characterization of CD44v3 Containing Isoforms in Head and Neck CancerErika P. Reategui, Adriana Antunez de Mayolo, Parpha M. Das, Frank C. Astor, Rakesh Singal, Kara L. Hamilton, W. Jarrard Goodwin, Kermit L. Carraway and Elizabeth J.
Aaron D, Nelson, Jennifer R, Grandis
openaire +2 more sources
Molecular and clinical aspects of HNSCC in the Republic of Moldova
Romanian Journal of Laboratory Medicine, 2023 Introduction: Complex molecular characterization and integrated approaches in the basic research of HNSCC provide new insights into the understanding and treatment of these tumors.
Stratan Valentina +9 more
doaj +1 more source
Autoimmunity, 2023 Lysosomal associated membrane protein 3 (LAMP3) has been reported to be a tumour promoter in multiple cancer types by modulating tumour cell autophagy. However, the potential mechanism of LAMP3 in radio-resistance of head and neck squamous cell carcinoma
Huixiang Lu +5 more
doaj +1 more source
Neoadjuvant chemotherapy in oral cancer: Current status and future possibilities
Cancer Research, Statistics, and Treatment, 2020 Eighty-five percent of oral cavity cancers present as locally advanced disease and are treated with multimodality approach. Patients who can undergo radical resection have the best outcomes, although the overall results are still unsatisfactory ...
Alok Goel, Anshul Singla, Kumar Prabhash
doaj +1 more source
Cancer Biology & Therapy, 2022 In this study, we report a differential response of mitogen-activated protein kinase–kinase (MEK) inhibitor trametinib in 20 head and neck squamous cell carcinoma (HNSCC) patients’ tumor-derived cell cultures.
Myles Vigoda +14 more
doaj +1 more source
Prognostic Value of FST and Relevance to Immune Infiltration in Head and Neck Squamous Cell Carcinoma. [PDF]
World J Otorhinolaryngol Head Neck SurgABSTRACT Background Immunotherapy response rates in head and neck squamous cell carcinoma (HNSCC) are limited by multiple factors. Tumor cell‐derived follistatin (FST) has been linked to immunotherapy resistance, but the underlying mechanisms remain poorly understood. This study aimed to investigate the prognostic value of FST and its associations with
Song P +6 more
europepmc +2 more sources