Results 21 to 30 of about 32,692 (251)

Inflammation-Related Gene Signature for Predicting the Prognosis of Head and Neck Squamous Cell Carcinoma

International Journal of General Medicine, 2022
Yilong Lu,1 Zengrong Jia2 1School of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of ...
Lu Y, Jia Z
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Design and Synthesis of Arf1-Targeting γ-Dipeptides as Potential Agents against Head and Neck Squamous Cell Carcinoma

Cells, 2020
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer-related deaths and calls for new druggable targets. We have previously highlighted the critical role of ADP-ribosylation factor-1 (Arf1) activation in HNSCC.
Yen Vo-Hoang, Sergio Paiva, Leilei He, Sébastien Estaran, Yong Teng   +4 more
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The Impact of YRNAs on HNSCC and HPV Infection

Biomedicines, 2023
HPV infection is one of the most important risk factors for head and neck squamous cell carcinoma among younger patients. YRNAs are short non-coding RNAs involved in DNA replication. YRNAs have been found to be dysregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC).
Kacper Guglas, Tomasz Kolenda, Joanna Kozłowska-Masłoń, Patricia Severino, Anna Teresiak, Renata Bliźniak, Katarzyna Lamperska   +6 more
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Anti-CD47 treatment enhances anti-tumor T-cell immunity and improves immunosuppressive environment in head and neck squamous cell carcinoma

OncoImmunology, 2018
Head and neck squamous cell carcinoma (HNSCC) is considered as an immunosuppressive disease, with impaired tumor-infiltrating T lymphocytes and increased suppressive immune cells.
Lei Wu, Guang-Tao Yu, Wei-Wei Deng, Liang Mao, Lei-Lei Yang, Si-Rui Ma, Lin-Lin Bu, Ashok B. Kulkarni, Wen-Feng Zhang, Lu Zhang, Zhi-Jun Sun   +10 more
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Research Progress of Ferroptosis in Head and Neck Squamous Cell Carcinoma

Zhongliu Fangzhi Yanjiu, 2022
Squamous cell carcinoma of the head and neck (HNSCC) is one of the cancers with the highest incidence rate in the world. Due to the presence of postoperative recurrence and resistance to some chemotherapeutics after the surgery, the prognosis of advanced
XIE Zhanghong, HUA Qingquan
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Exosomal microRNAs Targeting TP53 Gene as Promising Prognostic Markers for Head and Neck Squamous Cell Carcinoma

Global Medical Genetics, 2022
Statement of Problem MicroRNAs are small non-coding RNAs that regulate an array of functions by targeting crucial genes. A significant dysregulation in the TP53 profile has been observed in the head and neck squamous cell carcinoma (HNSCC) patients ...
Vijayashree Priyadharsini Jayaseelan, Paramasivam Arumugam   +1 more
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Associations of GWAS-Identified Risk Loci with Progression, Efficacy and Toxicity of Radiotherapy of Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy

Pharmacogenomics and Personalized Medicine, 2021
Qinghuan Li,1,* Yi Liang,1,* Zeng Liu,2 Chuanyun Yu1 1Oncology Radiotherapy Center, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, 441021, People’s Republic of China; 2Department of ...
Li Q, Liang Y, Liu Z, Yu C
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Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma

Biomolecules, 2019
STAT3 is a latent transcription factor that plays a vital role in the transmission of extracellular signal from receptors to the nucleus. It has been regarded as a master transcription factor due to its role in the regulation of a broad spectrum of genes,
Jong Hyun Lee, Shobith Rangappa, Chakrabhavi Dhananjaya Mohan, Basappa, Gautam Sethi, Zhi-Xiu Lin, Kanchugarakoppal S. Rangappa, Kwang Seok Ahn   +7 more
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Depth of tumor infiltration as a prognosticator in pT1-2 cN0 oral squamous cell carcinoma thereby need for elective neck dissection – A meta-analysis

Cancer Research, Statistics, and Treatment, 2019
Aim: The aim of the study is to identify the cutoff value for depth of infiltration that predicts the risk of lymph node metastasis in the neck in surgically treated patients affected by pT1/pT2 cN0 oral squamous cell carcinoma (OSCC).
Mohammad Akheel, Rinku K George, Amit Jain, Qutubuddin Chahwala, Ashmi Wadhwania   +4 more
doaj   +1 more source

PRF1 is a prognostic marker and correlated with immune infiltration in head and neck squamous cell carcinoma

Translational Oncology, 2021
Purpose: Head and neck squamous cell carcinoma (HNSCC) is a highly invasive malignancy with poor survival. Perforin (PRF1) plays essential roles in host immunity.
Cui Fan, Haixia Hu, Yilin Shen, Quan Wang, Yufeng Mao, Bin Ye, Mingliang Xiang   +6 more
doaj   +1 more source