Results 21 to 30 of about 32,408 (167)
Neoadjuvant chemotherapy in oral cancer: Current status and future possibilities
Cancer Research, Statistics, and Treatment, 2020 Eighty-five percent of oral cavity cancers present as locally advanced disease and are treated with multimodality approach. Patients who can undergo radical resection have the best outcomes, although the overall results are still unsatisfactory ...
Alok Goel, Anshul Singla, Kumar Prabhash
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Cancer Biology & Therapy, 2022 In this study, we report a differential response of mitogen-activated protein kinase–kinase (MEK) inhibitor trametinib in 20 head and neck squamous cell carcinoma (HNSCC) patients’ tumor-derived cell cultures.
Myles Vigoda +14 more
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In vivo CRISPR screens reveal potent driver mutations in head and neck cancers
Molecular & Cellular Oncology, 2020 We have recently tested the transforming potential of 484 ‘long-tail’ genes, which are recurrently albeit infrequently mutated in head and neck cancers (HNSCC).
Sampath Kumar Loganathan +1 more
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Polish Journal of Pathology, 2022 The aim of the study was to compare prognostic potential of PIK3CA mutations and expression of proteins involved in or regulate EGFR/PI3K/Akt/mTOR signaling in HPV16 positive and HPV negative head and neck squamous cell carcinoma (HNSCC) patients.
Anna Janecka-Widła +3 more
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Benzyl Isothiocyanate Inhibits HNSCC Cell Migration and Invasion, and Sensitizes HNSCC Cells to Cisplatin [PDF]
Nutrition and Cancer, 2014 Metastasis and chemoresistance represent two detrimental events that greatly hinder the outcome for those suffering with head and neck squamous cell carcinoma (HNSCC). Herein, we investigated benzyl isothiocyanate's (BITC) ability to inhibit HNSCC migration and invasion and enhance chemotherapy.
M Allison, Wolf, Pier Paolo, Claudio
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OncoImmunology, 2018 The immune environment of primary tumor is associated with the clinical response and benefit of immunotherapy. This study aims to investigate the intratumoral immune profile and its clinical relevance in advanced head and neck squamous cell carcinoma ...
Bangrong Cao +4 more
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ULK1 in autophagy: sugar it up
Autophagy Reports, 2022 Autophagy is a highly conserved cellular degradation and recycling process in mammalian cells, which is comprised of three main types: microautophagy, macroautophagy, and chaperone-mediated autophagy (CMA).
Sheng Yan, Jing Li
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Cancer Research, Statistics, and Treatment, 2022 Background: Head-and-neck squamous cell cancers (HNSCC) are common in India. Recurrent and metastatic HNSCC carry a poor prognosis. The chemotherapy options are limited, and the median survival is measured in months.
Rup J Sarma +5 more
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The Impact of YRNAs on HNSCC and HPV Infection
Biomedicines, 2023 HPV infection is one of the most important risk factors for head and neck squamous cell carcinoma among younger patients. YRNAs are short non-coding RNAs involved in DNA replication. YRNAs have been found to be dysregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC).
Kacper Guglas +6 more
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International Journal of General Medicine, 2022 Yilong Lu,1 Zengrong Jia2 1School of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of ...
Lu Y, Jia Z
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