Results 31 to 40 of about 47,439 (299)
Transforming Growth Factor Alpha Stimulation of Mucosal Tissue Cultures from Head and Neck Squamous Cell Carcinoma Patients Increases Chemoresistance to Cisplatin [PDF]
, 2010 The monoclonal epidermal growth factor receptor ( EGFR) antibody cetuximab (Erbitux(TM)) was recently approved by the European Medicines Agency for the treatment of recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) in combination ...
Baumeister, Philipp +7 more
core +1 more source
In vivo CRISPR screens reveal potent driver mutations in head and neck cancers
Molecular & Cellular Oncology, 2020 We have recently tested the transforming potential of 484 ‘long-tail’ genes, which are recurrently albeit infrequently mutated in head and neck cancers (HNSCC).
Sampath Kumar Loganathan +1 more
doaj +1 more source
IL-6 induces HNSCC cell migration.
, 2022 (A) HNSCC cells express IL-6R and gp130. Expression of IL-6R and gp130 determined by western blot analysis in the HNSCC cell lines SAS and FaDu. The experiment was repeated three times with similar results. (B) IL-6 increases HNSCC cell migration.
Satoshi Toyoma (12015167) +3 more
core +1 more source
Polish Journal of Pathology, 2022 The aim of the study was to compare prognostic potential of PIK3CA mutations and expression of proteins involved in or regulate EGFR/PI3K/Akt/mTOR signaling in HPV16 positive and HPV negative head and neck squamous cell carcinoma (HNSCC) patients.
Anna Janecka-Widła +3 more
doaj +1 more source
OncoImmunology, 2018 The immune environment of primary tumor is associated with the clinical response and benefit of immunotherapy. This study aims to investigate the intratumoral immune profile and its clinical relevance in advanced head and neck squamous cell carcinoma ...
Bangrong Cao +4 more
doaj +1 more source
Benzyl Isothiocyanate Inhibits HNSCC Cell Migration and Invasion, and Sensitizes HNSCC Cells to Cisplatin [PDF]
Nutrition and Cancer, 2014 Metastasis and chemoresistance represent two detrimental events that greatly hinder the outcome for those suffering with head and neck squamous cell carcinoma (HNSCC). Herein, we investigated benzyl isothiocyanate's (BITC) ability to inhibit HNSCC migration and invasion and enhance chemotherapy.
M Allison, Wolf, Pier Paolo, Claudio
openaire +2 more sources
, 2023 We characterized the immune context in HPV+ and HPV− HNSCC by integrating scRNA-seq and bulk RNA-seq data.
Zhongqiu Wang (14801422)
core +1 more source
ULK1 in autophagy: sugar it up
Autophagy Reports, 2022 Autophagy is a highly conserved cellular degradation and recycling process in mammalian cells, which is comprised of three main types: microautophagy, macroautophagy, and chaperone-mediated autophagy (CMA).
Sheng Yan, Jing Li
doaj +1 more source
The Impact of YRNAs on HNSCC and HPV Infection
Biomedicines, 2023 HPV infection is one of the most important risk factors for head and neck squamous cell carcinoma among younger patients. YRNAs are short non-coding RNAs involved in DNA replication. YRNAs have been found to be dysregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC).
Kacper Guglas +6 more
openaire +3 more sources
Histological evaluation of PD-L1 antibody in Head and Neck Squamous Cell Carcinomas (HNSCC)
, 2023 The thesis delves into the critical role of programmed death-ligand 1 (PD-L1) in Head and Neck Squamous Cell Carcinoma (HNSCC). PD-L1, a transmembrane protein found in tumor cells and immune cells, is expressed in higher amounts in specific cancer types,
Picanco Silva, Yasmin
core +1 more source