Results 31 to 40 of about 48,974 (212)
Benzyl Isothiocyanate Inhibits HNSCC Cell Migration and Invasion, and Sensitizes HNSCC Cells to Cisplatin [PDF]
Metastasis and chemoresistance represent two detrimental events that greatly hinder the outcome for those suffering with head and neck squamous cell carcinoma (HNSCC). Herein, we investigated benzyl isothiocyanate's (BITC) ability to inhibit HNSCC migration and invasion and enhance chemotherapy.
M Allison, Wolf, Pier Paolo, Claudio
openaire +2 more sources
ULK1 in autophagy: sugar it up
Autophagy is a highly conserved cellular degradation and recycling process in mammalian cells, which is comprised of three main types: microautophagy, macroautophagy, and chaperone-mediated autophagy (CMA).
Sheng Yan, Jing Li
doaj +1 more source
The Impact of YRNAs on HNSCC and HPV Infection
HPV infection is one of the most important risk factors for head and neck squamous cell carcinoma among younger patients. YRNAs are short non-coding RNAs involved in DNA replication. YRNAs have been found to be dysregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC).
Kacper Guglas +6 more
openaire +3 more sources
Background: Head-and-neck squamous cell cancers (HNSCC) are common in India. Recurrent and metastatic HNSCC carry a poor prognosis. The chemotherapy options are limited, and the median survival is measured in months.
Rup J Sarma +5 more
doaj +1 more source
FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma [PDF]
Background Currently, ferritin heavy chain (FTH1) has been increasingly found to play a crucial role in cancer as a core regulator of ferroptosis, while its role of non-ferroptosis in head and neck squamous cell carcinoma (HNSCC) is still unclear ...
Qingyun Liao +9 more
doaj +2 more sources
Aberrant Methylation of MGMT Promoter in HNSCC: A Meta-Analysis. [PDF]
O6-methylguanine-DNA methyl-transferase (MGMT) gene, a DNA repair gene, plays a critical role in the repair of alkylated DNA adducts that form following exposure to genotoxic agents.
Hao Shi (158171) +9 more
core +1 more source
Yilong Lu,1 Zengrong Jia2 1School of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of ...
Lu Y, Jia Z
doaj
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer-related deaths and calls for new druggable targets. We have previously highlighted the critical role of ADP-ribosylation factor-1 (Arf1) activation in HNSCC.
Yen Vo-Hoang +4 more
doaj +1 more source
ZMIZ1 metagene within the TCGA Head & Neck Squamous Cell Carcinoma (hnSCC) RNA-seq dataset.
(A) ZMIZ1 metagene heatmap constructed using singular value decomposition of human hnSCC RNA-seq dataset from TCGA consisting of a 23-gene signature. Multivariate analysis of a gene signatures that correlates with the expression of ZMIZ1 in HNSCC.
Amanda L. Meshey (11278937) +20 more
core +1 more source
Head and neck squamous cell carcinoma (HNSCC) is considered as an immunosuppressive disease, with impaired tumor-infiltrating T lymphocytes and increased suppressive immune cells.
Lei Wu +10 more
doaj +1 more source

