Results 51 to 60 of about 32,408 (167)

Bitter melon reduces head and neck squamous cell carcinoma growth by targeting c-Met signaling. [PDF]

PLoS ONE, 2013
Head and neck squamous cell carcinoma (HNSCC) remains difficult to treat, and despite of advances in treatment, the overall survival rate has only modestly improved over the past several years.
Ananthi Rajamoorthi, Shubham Shrivastava, Robert Steele, Pratibha Nerurkar, Juan G Gonzalez, Susan Crawford, Mark Varvares, Ratna B Ray   +7 more
doaj   +1 more source

Review of biomarkers for response to immunotherapy in HNSCC microenvironment

Frontiers in Oncology, 2023
Head and neck squamous cell carcinoma are one of the most common types of cancer worldwide. Although a variety of treatment methods such as surgery, radiotherapy, chemotherapy, and targeted therapy are widely used in diagnosing and treating HNSCC, the survival prognosis of patients has not been significantly improved in the past decades. As an emerging
Shaoshi Chen, Yifan Yang, Shizhi He, Meng Lian, Ru Wang, Jugao Fang   +5 more
openaire   +3 more sources

Deciphering a Prognostic Signature Based on Soluble Mediators Defines the Immune Landscape and Predicts Prognosis in HNSCC

Frontiers in Bioscience-Landmark
Background: The study on Head and Neck Squamous Cell Carcinoma (HNSCC), a prevalent and aggressive form of head and neck cancer, focuses on the often-overlooked role of soluble mediators.
Hao Chi, Gaoge Peng, Guobin Song, Jinhao Zhang, Xixi Xie, Jinyan Yang, Jiayu Xu, Jieying Zhang, Ke Xu, Qibiao Wu, Guanhu Yang   +10 more
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Long non-coding RNA DUXAP9 promotes the proliferation and metastasis of head and neck squamous cell carcinoma

口腔疾病防治, 2022
Objective To investigate the role of long non-coding RNA double homeobox A pseudogene 9 (DUXAP9) in head and neck squamous cell carcinoma (HNSCC) and to evaluate the expression level, molecular function and mechanism of DUXAP9 in HNSCC cells.
ZHOU Wenkai, WANG Jiaxuan, WANG Yuanfeng, CHEN Meng, TAO Xingru, LIU Zheqi, ZHANG Xu, JI Tong, CAO Wei   +8 more
doaj   +1 more source

Nivolumab Doubles Survival for Patients with HNSCC [PDF]

Cancer Discovery, 2016
Abstract In patients with head and neck squamous cell carcinoma refractory to platinum-based chemotherapy, those treated with nivolumab had a 30% reduction in the risk of death compared with those assigned to receive one of three single-agent chemotherapies, according to a recent phase III trial.
openaire   +2 more sources

CD73 is associated with poor prognosis in HNSCC

Oncotarget, 2016
CD73 is a cell surface immunosuppressive enzyme involved in tumor progression and metastasis. While patients whose cancer cells express elevated CD73 are typically associated with an unfavorable outcome, the clinical impact of CD73 expression in patients with Head and neck squamous cell carcinoma (HNSCC) remains unclear.
Ren, Zhen-Hu, Lin, Cheng-Zhong, Cao, Wei, Yang, Rong, Lu, Wei, Liu, Zhe-Qi, Chen, Yi-Ming, Yang, Xi, Tian, Zhen, Wang, Li-Zhen, Li, Jiang, Wang, Xu, Chen, Wan-Tao, Ji, Tong, Zhang, Chen-Ping   +14 more
openaire   +3 more sources

PD-L1 in Combination with CD8+TIL and HIF-1α are Promising Prognosis Predictors of Head and Neck Squamous Cell Carcinoma

Cancer Management and Research, 2020
Zihan Zhou,1,2 Dianbin Mu,3 Dexian Zhang,3 Xianbin Zhang,2 Xingchen Ding,2 Jia Yang,2 Xinbin Bai,4 Man Hu2 1Department of Oncology, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2Department of Radiation Oncology ...
Zhou Z, Mu D, Zhang D, Zhang X, Ding X, Yang J, Bai X, Hu M   +7 more
doaj  

Cetuximab Plus Chemotherapy versus Chemotherapy Alone in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Cost-Effectiveness Analysis

Cancer Management and Research, 2020
Yitian Lang,1,2 Deshi Dong1,2 1Department of Pharmacy, The First Affiliated Hospital of Dalian Medical University, Dalian, People’s Republic of China; 2College of Pharmacy, Dalian Medical University, Dalian, People’s Republic of ...
Lang Y, Dong D
doaj  

The RNA N6-Methyladenosine Demethylase FTO Promotes Head and Neck Squamous Cell Carcinoma Proliferation and Migration by Increasing CTNNB1

International Journal of General Medicine, 2021
Yu Zhang,1 Lixiao Chen,1 Xiaoliang Wu,2 Zhenfeng Sun,1 Fei Wang,1 Baoxin Wang,1 Pin Dong1 1Department of Otolaryngology, Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ...
Zhang Y, Chen L, Wu X, Sun Z, Wang F, Wang B, Dong P   +6 more
doaj  

The Mapk-Jun-Tnnt1 Pathway Promotes Proliferation, Metastasis Of Hnscc

International Dental Journal
Aim or purpose: To validate the role of TNNT1 in the proliferation, invasion, migration, and cytoskeletal remodeling of tongue cancer. Materials and methods: Specific siRNA was used to silence TNNT1 in highly metastatic cells, while a TNNT1 ...
Jing Xie
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