Results 11 to 20 of about 32,408 (167)
Targeting EGFR Exon 20 Insertion-mutated Cancers – New Perspectives in Head and Neck Cancers – Lessons to Learn from Non-small Cell Carcinoma (NSCLC) [PDF]
Modern Medicine, 2022 Mutations in the tyrosine kinase (TKD) domain of the epidermal growth factor receptor (EGFR) are involved in the unfavorable therapeutic response through resistance to targeted molecular therapy.
Camil Ciprian MIRESTEAN +2 more
doaj +1 more source
NR2F6 as a Prognostic Biomarker in HNSCC [PDF]
International Journal of Molecular Sciences, 2020 Head and neck squamous cell carcinoma (HNSCC)is the 6th most common cancer in humans worldwide and is associated with a poor prognosis for patients. NR2F6 has been identified as an immune checkpoint molecule in tumor-infiltrating T lymphocytes and is associated with a poor prognostic outcome in various cancers.
Luise Klapper +10 more
openaire +2 more sources
Cancer Research, Statistics, and Treatment, 2021 Background: The sarcomatoid variant of squamous cell carcinoma (SCC) is an uncommon variant of head-and-neck cancer with a clinically aggressive course and poor outcomes. The data on the clinical presentation and pattern of treatment received by patients
Adhara Chakraborthy +3 more
doaj +1 more source
Epithelial-Mesenchymal Transition and Inflammation in Head and Neck Squamous Cell Carcinoma [PDF]
Journal of Sciences, Islamic Republic of Iran, 2020 Head and neck squamous cell carcinoma (HNSCC) represents a large majority of cancers arising from the head and neck, especially the oral cavity. Despite advances in therapy, the five-year survival rate remains low due to the number of patients presenting
Habib Sadeghi Rad +4 more
doaj +1 more source
Incidence and survival of HNSCC patients living with HIV compared with HIV-negative HNSCC patients [PDF]
European Archives of Oto-Rhino-Laryngology, 2021 Abstract Purpose The aim was to analyze the incidence and survival of patients living with HIV (PLWH) with head and neck squamous cell carcinoma (HNSCC) and to compare with a control group of HIV-negative HNSCC patients.
Katharina Haase +15 more
openaire +2 more sources
The role of CD44 in HNSCC [PDF]
Cancer Biology & Therapy, 2007 Commentary to:Characterization of CD44v3 Containing Isoforms in Head and Neck CancerErika P. Reategui, Adriana Antunez de Mayolo, Parpha M. Das, Frank C. Astor, Rakesh Singal, Kara L. Hamilton, W. Jarrard Goodwin, Kermit L. Carraway and Elizabeth J.
Aaron D, Nelson, Jennifer R, Grandis
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Molecular and clinical aspects of HNSCC in the Republic of Moldova
Romanian Journal of Laboratory Medicine, 2023 Introduction: Complex molecular characterization and integrated approaches in the basic research of HNSCC provide new insights into the understanding and treatment of these tumors.
Stratan Valentina +9 more
doaj +1 more source
Autoimmunity, 2023 Lysosomal associated membrane protein 3 (LAMP3) has been reported to be a tumour promoter in multiple cancer types by modulating tumour cell autophagy. However, the potential mechanism of LAMP3 in radio-resistance of head and neck squamous cell carcinoma
Huixiang Lu +5 more
doaj +1 more source
lncRNA in HNSCC: challenges and potential [PDF]
Współczesna Onkologia, 2017 Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cause of cancer mortality in the world. Some progress has been made in the therapy of HNSCC, however treatment remains unsatisfactory. Recent studies have shown that different types of long non-coding RNAs (lncRNAs) are dysregulated in HNSCC and correlate with tumor progression ...
Kacper Guglas +8 more
openaire +3 more sources
NF-Y Subunits Overexpression in HNSCC [PDF]
Cancers, 2021 NF-Y is the CCAAT-binding trimer formed by the histone fold domain (HFD), NF-YB/NF-YC and NF-YA. The CCAAT box is generally prevalent in promoters of “cancer” genes. We reported the overexpression of NF-YA in BRCA, LUAD and LUSC, and of all subunits in HCC. Altered splicing of NF-YA was found in breast and lung cancer.
Eugenia Bezzecchi +6 more
openaire +2 more sources