Results 11 to 20 of about 32,692 (251)

NR2F6 as a Prognostic Biomarker in HNSCC [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Head and neck squamous cell carcinoma (HNSCC)is the 6th most common cancer in humans worldwide and is associated with a poor prognosis for patients. NR2F6 has been identified as an immune checkpoint molecule in tumor-infiltrating T lymphocytes and is associated with a poor prognostic outcome in various cancers.
Luise Klapper   +10 more
openaire   +2 more sources

Incidence and survival of HNSCC patients living with HIV compared with HIV-negative HNSCC patients [PDF]

open access: yesEuropean Archives of Oto-Rhino-Laryngology, 2021
Abstract Purpose The aim was to analyze the incidence and survival of patients living with HIV (PLWH) with head and neck squamous cell carcinoma (HNSCC) and to compare with a control group of HIV-negative HNSCC patients.
Katharina Haase   +15 more
openaire   +2 more sources

The role of CD44 in HNSCC [PDF]

open access: yesCancer Biology & Therapy, 2007
Commentary to:Characterization of CD44v3 Containing Isoforms in Head and Neck CancerErika P. Reategui, Adriana Antunez de Mayolo, Parpha M. Das, Frank C. Astor, Rakesh Singal, Kara L. Hamilton, W. Jarrard Goodwin, Kermit L. Carraway and Elizabeth J.
Aaron D, Nelson, Jennifer R, Grandis
openaire   +2 more sources

lncRNA in HNSCC: challenges and potential [PDF]

open access: yesWspółczesna Onkologia, 2017
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cause of cancer mortality in the world. Some progress has been made in the therapy of HNSCC, however treatment remains unsatisfactory. Recent studies have shown that different types of long non-coding RNAs (lncRNAs) are dysregulated in HNSCC and correlate with tumor progression ...
Kacper Guglas   +8 more
openaire   +3 more sources

NF-Y Subunits Overexpression in HNSCC [PDF]

open access: yesCancers, 2021
NF-Y is the CCAAT-binding trimer formed by the histone fold domain (HFD), NF-YB/NF-YC and NF-YA. The CCAAT box is generally prevalent in promoters of “cancer” genes. We reported the overexpression of NF-YA in BRCA, LUAD and LUSC, and of all subunits in HCC. Altered splicing of NF-YA was found in breast and lung cancer.
Eugenia Bezzecchi   +6 more
openaire   +2 more sources

Two immune-enhanced molecular subtypes differ in inflammation, checkpoint signaling and outcome of advanced head and neck squamous cell carcinoma

open access: yesOncoImmunology, 2018
The immune environment of primary tumor is associated with the clinical response and benefit of immunotherapy. This study aims to investigate the intratumoral immune profile and its clinical relevance in advanced head and neck squamous cell carcinoma ...
Bangrong Cao   +4 more
doaj   +1 more source

Benzyl Isothiocyanate Inhibits HNSCC Cell Migration and Invasion, and Sensitizes HNSCC Cells to Cisplatin [PDF]

open access: yesNutrition and Cancer, 2014
Metastasis and chemoresistance represent two detrimental events that greatly hinder the outcome for those suffering with head and neck squamous cell carcinoma (HNSCC). Herein, we investigated benzyl isothiocyanate's (BITC) ability to inhibit HNSCC migration and invasion and enhance chemotherapy.
M Allison, Wolf, Pier Paolo, Claudio
openaire   +2 more sources

ULK1 in autophagy: sugar it up

open access: yesAutophagy Reports, 2022
Autophagy is a highly conserved cellular degradation and recycling process in mammalian cells, which is comprised of three main types: microautophagy, macroautophagy, and chaperone-mediated autophagy (CMA).
Sheng Yan, Jing Li
doaj   +1 more source

Paclitaxel with Mycidac-C in the second line and beyond in advanced head-and-neck cancer: A retrospective analysis from a tertiary cancer center

open access: yesCancer Research, Statistics, and Treatment, 2022
Background: Head-and-neck squamous cell cancers (HNSCC) are common in India. Recurrent and metastatic HNSCC carry a poor prognosis. The chemotherapy options are limited, and the median survival is measured in months.
Rup J Sarma   +5 more
doaj   +1 more source

FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma [PDF]

open access: yesPeerJ, 2023
Background Currently, ferritin heavy chain (FTH1) has been increasingly found to play a crucial role in cancer as a core regulator of ferroptosis, while its role of non-ferroptosis in head and neck squamous cell carcinoma (HNSCC) is still unclear ...
Qingyun Liao   +9 more
doaj   +2 more sources

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