Results 111 to 120 of about 25,300,433 (384)

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

虚血再灌流腎におけるHeme Oxygenase-1（HO-1）の役割 [PDF]

, 2002
　The contribution of heme oxygenase-1 (HO-1) in ischemic renal injury is little known. To investigate the role of HO-1 in the kidney, we examined the role of HO-1 in the ischemic re-perfusion kidney and its functional significance of an induction of HO-1.
石田 祐二
core  

Chlorogenic acid protects against cisplatin-induced testicular damage: a biochemical and histological study

Arhiv za Higijenu Rada i Toksikologiju
One of the adverse effects of cisplatin (CIS) treatment is its reproductive toxicity, which limits its clinical use in male patients. The aim of our study was to investigate the potential protective effects and mechanisms of chlorogenic acid (CHA), a ...
Demir Elif Ayazoğlu, Demir Selim, Mungan Sevdegül Aydın, Alemdar Nihal Türkmen, Menteşe Ahmet, Aliyazıcıoğlu Yüksel   +5 more
doaj   +1 more source

Chlorogenic acid attenuates deoxynivalenol-induced apoptosis and pyroptosis in human keratinocytes via activating Nrf2/HO-1 and inhibiting MAPK/NF-κB/NLRP3 pathways [PDF]

, 2023
Jiashe Chen, Zhiyu Zhou, Ningyuan Xi, Mingyuan Xu, Nanhui Wu, Fei Wu, Qiaoting Fu, Guorong Yan, Yeqiang Liu, Xiaoxiang Xu   +9 more
openalex   +1 more source

Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 and inhibition of the NF-κB pathways

Respiratory Research, 2020
Background It is well established that airway remodeling and inflammation are characteristics for chronic obstructive pulmonary disease (COPD). Moreover, cigarette smoke extract (CSE) promots inflammation, apoptosis and oxidative stress in COPD.
Xiaomin Dang, Beibei He, Qian Ning, Ya Liu, Jianxin Guo, Gang Niu, Mingwei Chen   +6 more
semanticscholar   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Kinetics of n-Butoxy and 2-Pentoxy Isomerization and Detection of Primary Products by Infrared Cavity Ringdown Spectroscopy [PDF]

, 2012
The primary products of n-butoxy and 2-pentoxy isomerization in the presence and absence of O_2 have been detected using pulsed laser photolysis-cavity ringdown spectroscopy (PLP-CRDS).
Bean, Brian D., Bloss, Claire, Garland, Eva R., Mertens, Laura A., Mollner, Andrew K., Okumura, Mitchio, Sander, Stanley P., Sprague, Matthew K., Weichman, Marissa L.   +8 more
core   +1 more source

Curcumin ameliorates TNF-α-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells [PDF]

BMB Reports, 2013
Adhesion molecules such as ICAM-1 are important in theinfiltration of leukocytes into the site of inflammation. In thisstudy, we investigated the inhibitory effects of curcumin onICAM-1 expression and monocyte adhesiveness as well as itsunderlying action
Gi Soo Youn, Dong-Joo Kwon, Sung Mi Ju, Soo Young Choi, Jinseu Park   +4 more
doaj   +1 more source

Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway

Oxidative Medicine and Cellular Longevity, 2018
Oxidative stress plays a crucial role in the pathogenesis of acute pancreatitis (AP). Isoliquiritigenin (ISL) is a flavonoid monomer with confirmed antioxidant activity. However, the specific effects of ISL on AP have not been determined.
Xinnong Liu, Qingtian Zhu, Min Zhang, Tao Yin, Rong Xu, Weiming Xiao, Jian Wu, Bin Deng, Xuefeng Gao, W. Gong, Guotao Lu, Yanbing Ding   +11 more
semanticscholar   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source