Results 121 to 130 of about 25,300,433 (384)

Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation [PDF]

, 2012
Living donor liver transplantation (LDLT) requires ischemia/reperfusion (I/R), which can cause early graft injury. However, the detailed mechanism of I/R injury remains unknown.
Kaku, Ryuji, Matsumi, Junya, Matsumi, Masaki, Matsusaki, Takashi, Morimatsu, Hiroshi, Morita, Kiyoshi, Shimizu, Hiroko, Takahashi, Toru, Yagi, Takahito   +8 more
core   +1 more source

Retracted: ALK7 Knockdown Plays a Protective Role on HG-Stimulated MCs through Activation of the Nrf2/HO-1 Pathway [PDF]

, 2023
Disease Markers
openalex   +1 more source

HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB

Aging, 2020
In this study, we investigated the role of heme oxygenase-1 (HO-1) in intervertebral disc degeneration (IDD) by assessing the effects of HO-1 overexpression on IL-1β-induced apoptosis in nucleus pulposus cells (NPCs).
Luetao Zou, Hongyan Lei, Jieliang Shen, Xulin Liu, Xiang Zhang, Longxi Wu, J. Hao, Wei Jiang, Zhenming Hu   +8 more
semanticscholar   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Adeno-associated virus-mediated heme oxygenase-1 gene transfer suppresses the progression of micronodular cirrhosis in rats [PDF]

, 2006
Aim: To test the hypothesis that enhancement of the activity of heme oxygenase can interfere with processes of fibrogenesis associated with recurrent liver injury, we investigated the therapeutic potential of over-expression of heme oxygense-1 in a CCI 4-
Fan, ST, Glockzin, G, Lau, CK, Ma, J, Obed, A, Schlitt, HJ, Tsui, TY   +6 more
core   +1 more source

Betula etnensis Raf. (Betulaceae) Extract Induced HO-1 Expression and Ferroptosis Cell Death in Human Colon Cancer Cells

International Journal of Molecular Sciences, 2019
Betula etnensis Raf. (Birch Etna) belonging to the Betulaceae family grows on the eastern slope of Etna. Many bioactive compounds present in Betula species are considered promising anticancer agents. In this study, we evaluated the effects of B. etnensis
G. Malfa, Barbara Tomasello, R. Acquaviva, C. Genovese, A. La Mantia, Francesco Paolo Cammarata, M. Ragusa, M. Renis, C. Di Giacomo   +8 more
semanticscholar   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Catalase Prevents Maternal Diabetes–Induced Perinatal Programming via the Nrf2–HO-1 Defense System [PDF]

, 2014
We investigated whether overexpression of catalase (CAT) in renal proximal tubular cells (RPTCs) could prevent the programming of hypertension and kidney disease in the offspring of dams with maternal diabetes.
Chang, Shiao-Ying, Chen, Yun-Wen, Chenier, Isabelle, Ingelfinger, Julie R., Sauvé, Alexandre, Tran, Stella, Zhang, Shao-Ling, Zhao, Xin-Ping   +7 more
core   +1 more source

Antioxidant efficacy and the upregulation of Nrf2-mediated HO-1 expression by (+)-lariciresinol, a lignan isolated from Rubia philippinensis, through the activation of p38

Scientific Reports, 2017
The aim of the present study was to examine the antioxidative activity of (+)-lariciresinol (LRSL), an optically active lignan isolated from Rubia philippinensis in several in vitro assays.
V. Bajpai, M. Alam, Khong Trong Quan, Kyoo-Ri Kwon, Mi-Kyoung Ju, Hee‐Jeong Choi, Jong Sung Lee, J. Yoon, R. Majumder, I. Rather, Kangmin Kim, Sang-Han Lee, M. Na   +12 more
semanticscholar   +1 more source

Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat

Journal of Neuroinflammation, 2020
Background Recently, depression has been identified as a prevalent and severe mental disorder. However, the mechanisms underlying the depression risk remain elusive.
Hetao Bian, Gaohua Wang, Junjie Huang, L. Liang, Yage Zheng, Yanyan Wei, Hui Wang, L. Xiao, Hui-ling Wang   +8 more
semanticscholar   +1 more source