Pediatric Blood &Cancer, EarlyView.ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser +6 more
wiley +1 more source
Relationship between NOX4 level and angiotensin II signaling in Gitelman's syndrome. Implications with hypertension [PDF]
, 2015 Recent evidence showed that endogenous nicotinamide adenine dinucleotide phosphate-oxidase 4 (NOX4) may exert a protective role on the cardiovascular system inducing vasodilation, reduction of blood pressure, and anti-proliferative actions.
Calò, Lorenzo A +5 more
core
Phenomenological Theory of Superconductivity and Magnetism in Ho$_{1-x}$Dy$_x$Ni$_2$B$_2$C
, 1999 The coexistence of the superconductivity and magnetism in the Ho$_{1-x}$Dy$_x$Ni$_2$B$_2$C is studied by using Ginzburg-Landau theory. This alloy shows the coexistence and complex interplay of superconducting and magnetic order.
A. Amici +20 more
core +1 more source
Identification and characterization of [6]-shogaol from ginger as inhibitor of vascular smooth muscle cell proliferation [PDF]
, 2015 Scope Vascular smooth muscle cell (VSMC) proliferation is involved in the pathogenesis of cardiovascular disease, making the identification of new counteracting agents and their mechanisms of action relevant.
Andreas Schinkovitz +10 more
core +4 more sources
Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): This investigation explored the mechanism by which the total flavonoids of Selaginella tamariscina (P.Beauv.) Spring (TFST) mitigate oxidative stress through the activation of the heme oxygenase-1 (HO-1) signaling pathway mediated by ...
Lina Chen +4 more
doaj +1 more source
The role of Nrf2 in astragaloside IV-mediated antioxidative protection on heart failure
Pharmaceutical Biology, 2020 Context Heart failure is one of the most serious diseases worldwide. Astragaloside IV (ASI) is widely used in the treatment of cardiovascular diseases.
Yan-Bo Sui +4 more
doaj +1 more source
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis [PDF]
, 2023 Min Yang +4 more
openalex +1 more source
Bioscience Reports, 2018 Background and aims: Diabetic kidney is more sensitive to ischemia/reperfusion (I/R) injury, which is associated with increased oxidative stress and impaired nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling. Melatonin,
Si Shi +4 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd +3 more
wiley +1 more source
Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice [PDF]
, 2017 Hepcidin, a phase II reactant secreted by hepatocytes, regulates cellular iron levels by increasing internalization of ferroportin-a transmembrane protein facilitating egress of cellular iron.
Arefiev, Yevgeniy +12 more
core +2 more sources