Results 11 to 20 of about 395,589 (199)

Effect of vanillic acid on pentylenetetrazole-kindled rats: Nrf2/HO-1, IGF-1 signaling pathways cross talk [PDF]

Journal of Integrative Neuroscience, 2022
Vanillic acid (VA) exhibited antioxidant and neuroprotective properties in some neurodegenerative disorders. So, the current study examined the neuroprotective potential of VA as an antiepileptic agent in pentylenetetrazole (PTZ)-induced epileptic ...
Mahmoud A. El-Hefnawy, Asmaa Yehia, Eman M. El Nashar, Somaya Saad, Walaa Obydah, Mansour A. Alghamdi, Wardah A. Alasmari, Abdelaziz M. Hussein   +7 more
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Acacetin alleviates neuroinflammation and oxidative stress injury via the Nrf2/HO-1 pathway in a mouse model of spinal cord injury

Translational Neuroscience, 2022
Spinal cord injury (SCI) is a severe central nervous system disease, which may cause serious locomotor deficit. Acacetin is a flavone that possesses antioxidant and anti-inflammatory effects in different human diseases. The main purpose of this study was
Zhang Xin, Xu Lijun, Chen Xiang, Zhou Xianjie, Cao Lanhua   +4 more
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Study protocol: The clinical features, epidemiology, and causes of paediatric encephalitis in southern Vietnam [version 3; peer review: 2 approved]

Wellcome Open Research, 2022
Encephalitis is a major cause of morbidity and mortality worldwide. The clinical syndrome of encephalitis consists of altered mental status, seizures, neurologic signs, and is often accompanied by fever, headache, nausea, and vomiting.
Ngo Ngoc Quang Minh, Le Nguyen Thanh Nhan, Louise Thwaites, Hugo Turner, Nguyen Thanh Hung, Sarosh Irani, Le Van Tan, Nguyen Hoang Thien Huong, Du Tuan Quy, Nguyen Duc Toan, Le Quoc Thinh, Truong Huu Khanh   +11 more
doaj   +1 more source

Luteolin attenuates PM2.5-induced inflammatory responses by augmenting HO-1 and JAK-STAT expression in murine alveolar macrophages

Food and Agricultural Immunology, 2022
To explore the involved mechanisms and possible treatments of ambient PM2.5 exposure-induced lung inflammation, this work studied the activity of luteolin, a natural flavonoid which widely presents in many plant species, in murine alveolar macrophage MH ...
Wen-Che Hsieh, Chane-Yu Lai, Hui-Wen Lin, Dom-Gene Tu, Ting-Jing Shen, Yi-Ju Lee, Ming-Chang Hsieh, Ching-Chung Chen, Hsin-Hsuan Han, Yuan-Yen Chang   +9 more
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Nrf2/HO-1 Axis Regulates the Angiogenesis of Gastric Cancer via Targeting VEGF

Cancer Management and Research, 2021
Yunning Huang,1,* Yuanyuan Yang,2,* Yuanyi Xu,2,* Qian Ma,3,4,* Fengying Guo,2 Yuan Zhao,2 Yuejia Tao,2 Mengqi Li,2 Jiaxin Guo2 1Department of Gastrointestinal Surgery, The Affiliated People’s Hospital of Ningxia Medical University, Yinchuan City ...
Huang Y, Yang Y, Xu Y, Ma Q, Guo F, Zhao Y, Tao Y, Li M, Guo J   +8 more
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Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α

Biomolecules, 2020
Mevastatin (MVS) has been previously shown to induce heme oxygenase (HO)-1 expression through Nox/ROS-dependent PDGFRα/PI3K/Akt/Nrf2/ARE axis in human pulmonary alveolar epithelial cells (HPAEpiCs).
Chuen-Mao Yang, Chih-Chung Lin, Chien-Chung Yang, Rou-Ling Cho, Li-Der Hsiao   +4 more
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The Modulatory Effect of Liraglutide on the Expression of GPX4, HO-1 and SLC7A11 Signaling Pathway in Obese Rats [PDF]

Pharmaceutical Sciences
Background: Obesity, a multifaceted metabolic condition, is associated with oxidative stress and disrupted redox homeostasis, leading to ferroptosis and metabolic dysfunction. Liraglutide, a well-known glucagon-like peptide-1 (GLP-1) receptor agonist, is
Mahmood Jameel Saeed, Inam Sameh Arif
doaj   +1 more source

CD40LG mutations in Vietnamese patients with X‐linked hyper‐IgM syndrome; catastrophic anti‐phospholipid syndrome as a new complication

Molecular Genetics & Genomic Medicine, 2021
Background X‐linked hyper‐IgM syndrome (XHIGM) is a rare primary immunodeficiency caused by CD40 ligand defects. Methods We identified three patients with XHIGM in Ho Chi Minh City, Vietnam. Whole‐exome sequencing, immunological analyses and western blot
Anh Nguyen Lien Phan, Thuy Thi Thanh Pham, Xinh Thi Phan, Nghia Huynh, Tuan Minh Nguyen, Cuc Tran Thu Cao, Duong Thuy Nguyen, Khanh Thi Xuan Luong, Tam Thi Minh Nguyen, Anh Ngoc Kim Tran, Linh Thi Truc Pham, Vy Vuong Thao Nguyen, Sigrid Swagemakers, Chi‐Bao Bui, Petrus Martinus Van Hagen   +14 more
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Leukemia Inhibitory Factor Attenuates Hypoxic–Ischemic White Matter Injury via NLRP3 Inflammasome Activity Suppressing Through the Nrf2/HO-1 Pathway

Frontiers in Bioscience-Landmark
Background: Inhibiting neuroinflammatory damage is an effective strategy for treating preterm white matter injury (PWMI). Leukemia inhibitory factor (LIF) can ameliorate (HI) induced white matter injury; however, the neuroprotective ...
Liang Huo, Xueyan Liu, Hua Wang
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Efficacy of a novel water soluble curcumin derivative versus Tadalafile in mediating erectile function [PDF]

Journal of Bioscience and Applied Research, 2015
The present study was conducted to assess the efficacy of a novel curcumin derivative (NCD) versus Tadalafile in erectile signaling. The study was conducted on 15 control male rats and 75 diabetic male rats divided into the following groups:, diabetic ...
SA.M. Zaahkouk, G.A Hesham, Yehia M. Hussein, H.M Atta, Fouad Hanan   +4 more
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