Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels [PDF]
Induction of the antioxidant enzyme heme oxygenase-1 (HO-1) affords cellular protection and suppresses proliferation of vascular smooth muscle cells (VSMCs) associated with a variety of pathological cardiovascular conditions including myocardial ...
A Panner +66 more
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Effects of Losartan, HO-1 Inducers or HO-1 Inhibitors on Erectile Signaling in Diabetic Rats
ABSTRACT Introduction Activation of the renin-angiotensin system which is common in diabetes mellitus might affect heme oxygenase (HO-1) gene expression. Aim Assessment of the effects of administration of angiotensin II (Ang II ...
Mohamed Talaat, Abdel Aziz +11 more
openaire +2 more sources
Cytoprotective role of heme oxygenase-1 and heme degradation derived end products in liver injury [PDF]
The activation of heme oxygenase-1 (HO-1) appears to be an endogenous defensive mechanism used by cells to reduce inflammation and tissue damage in a number of injury models. HO-1, a stress-responsive enzyme that catabolizes heme into carbon monoxide (CO)
Câmara, Niels Olsen Saraiva +1 more
core +1 more source
Differential expression of heme oxygenase-1 and vascular endothelial growth factor in cadaveric and living donor kidneys after ischemia-reperfusion [PDF]
The extent of graft damage after ischemia-reperfusion reflects the balance between deleterious events and protective factors. Heme oxygenase-1 (HO-1) and vascular endothelial growth factor (VEGF) may contribute to cytoprotection by ...
Baan, C.C. (Carla) +7 more
core +3 more sources
Background: Inhibiting neuroinflammatory damage is an effective strategy for treating preterm white matter injury (PWMI). Leukemia inhibitory factor (LIF) can ameliorate (HI) induced white matter injury; however, the neuroprotective ...
Liang Huo, Xueyan Liu, Hua Wang
doaj +1 more source
Efficacy of a novel water soluble curcumin derivative versus Tadalafile in mediating erectile function [PDF]
The present study was conducted to assess the efficacy of a novel curcumin derivative (NCD) versus Tadalafile in erectile signaling. The study was conducted on 15 control male rats and 75 diabetic male rats divided into the following groups:, diabetic ...
SA.M. Zaahkouk +4 more
doaj +1 more source
Implication of heme oxygenase-1 in the sensitivity of nasopharyngeal carcinomas to radiotherapy [PDF]
High expression of the inducible isoform of heme oxygenase (HO-1) is well known in various solid tumors in human and experimental animal models. To investigate the relationship between HO-1 and nasopharyngeal carcinomas, especially its involvement in the
Lei Shi, Jun Fang
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Induction of heme-oxygenase-1 (HO-1) does not enhance adiponectin production in human adipocytes: evidence against a direct HO-1 - Adiponectin axis [PDF]
Adiponectin is a salutary adipokine and hypoadiponectinemia is implicated in the aetiology of obesity-related inflammation and cardiometabolic disease making therapeutic strategies to increase adiponectin attractive. Emerging evidence, predominantly from
Barclay, Johanna L. +7 more
core +1 more source
Phenomenological Theory of Superconductivity and Magnetism in Ho$_{1-x}$Dy$_x$Ni$_2$B$_2$C
The coexistence of the superconductivity and magnetism in the Ho$_{1-x}$Dy$_x$Ni$_2$B$_2$C is studied by using Ginzburg-Landau theory. This alloy shows the coexistence and complex interplay of superconducting and magnetic order.
A. Amici +20 more
core +1 more source
HO-1 expression control in the rat glomerulus
The differential localization of HO-1 in renal cells under conditions of injury, and the demonstration that exaggerated HO-1 expression can have detrimental rather than beneficial effects, raises the question of whether HO-1 expression in these cells is subject to control.
Detsika, M.G., Duann, P., Lianos, E.A.
openaire +3 more sources

