Results 21 to 30 of about 22,040,645 (295)

EETs and HO-1 cross-talk

Prostaglandins & Other Lipid Mediators, 2016
Epoxygenase-dependent metabolites of arachidonc acid, EETs and the heme-oxygenase (HO)-1/carbon monoxide/bilverdin system share similarities in their activity and mediators. They control endothelial function, dilating small arterial vessels, decrease blood pressure, protect the heart from ischemic and hypertensive cardiopathy, control renal circulation
SACERDOTI, DAVID, PESCE, PAOLA, DI PASCOLI, MARCO, BOLOGNESI, MASSIMO   +3 more
openaire   +2 more sources

HO‐1/CO Maintains Intestinal Barrier Integrity through NF‐κB/MLCK Pathway in Intestinal HO‐1^-/- Mice [PDF]

Oxidative Medicine and Cellular Longevity, 2021
Background. Intestinal barrier injury is an important contributor to many diseases. We previously found that heme oxygenase‐1 (HO‐1) and carbon monoxide (CO) protect the intestinal barrier. This study is aimed at elucidating the molecular mechanisms of HO‐1/CO in barrier loss. Materials and Methods.
Zhenling Zhang, Lijing Zhang, Qiuping Zhang, Bojia Liu, Fang Li, Yi Xin, Zhijun Duan   +6 more
openaire   +2 more sources

Study protocol: The clinical features, epidemiology, and causes of paediatric encephalitis in southern Vietnam [version 3; peer review: 2 approved]

Wellcome Open Research, 2022
Encephalitis is a major cause of morbidity and mortality worldwide. The clinical syndrome of encephalitis consists of altered mental status, seizures, neurologic signs, and is often accompanied by fever, headache, nausea, and vomiting.
Ngo Ngoc Quang Minh, Le Nguyen Thanh Nhan, Louise Thwaites, Hugo Turner, Nguyen Thanh Hung, Sarosh Irani, Le Van Tan, Nguyen Hoang Thien Huong, Du Tuan Quy, Nguyen Duc Toan, Le Quoc Thinh, Truong Huu Khanh   +11 more
doaj   +1 more source

Recipient HO-1 inducibility is essential for posttransplant hepatic HO-1 expression and graft protection: From bench-to-bedside [PDF]

American Journal of Transplantation, 2019
By documenting potent antioxidative and anti-inflammatory functions, preclinical studies encourage heme oxygenase-1 (HO-1)-inducing regimens in clinical orthotopic liver transplantation (OLT). We aimed to determine the importance of recipient-derived HO-1 in murine and human OLTs. Hepatic biopsies from 51 OLT patients were screened for HO-1 expression (
Shoichi Kageyama, Hirofumi Hirao, Kojiro Nakamura, Bibo Ke, Min Zhang, Takahiro Ito, Antony Aziz, Damla Oncel, Fady M. Kaldas, Ronald W. Busuttil, Rebecca A. Sosa, Elaine F. Reed, Jesus A. Araujo, Jerzy W. Kupiec-Weglinski   +13 more
openaire   +5 more sources

HO-1 induction promotes M2 macrophage polarisation. [PDF]

, 2016
RAW 264.7 cells were transfected with siRNA HO-1 and siRNA NC (non-correlated). (A) RT-qPCR analysis of HO-1 mRNA in cells transfected 48 hours after transfection. Cells were treated with SP (10 μM) and/or LPS (100 ng/ml) for 24 hours and mRNA expression
Nadia Lampiasi (420771), Giovanna Montana (3372680)   +1 more
core   +1 more source

Luteolin attenuates PM2.5-induced inflammatory responses by augmenting HO-1 and JAK-STAT expression in murine alveolar macrophages

Food and Agricultural Immunology, 2022
To explore the involved mechanisms and possible treatments of ambient PM2.5 exposure-induced lung inflammation, this work studied the activity of luteolin, a natural flavonoid which widely presents in many plant species, in murine alveolar macrophage MH ...
Wen-Che Hsieh, Chane-Yu Lai, Hui-Wen Lin, Dom-Gene Tu, Ting-Jing Shen, Yi-Ju Lee, Ming-Chang Hsieh, Ching-Chung Chen, Hsin-Hsuan Han, Yuan-Yen Chang   +9 more
doaj   +1 more source

Effects of Losartan, HO-1 Inducers or HO-1 Inhibitors on Erectile Signaling in Diabetic Rats

The Journal of Sexual Medicine, 2009
ABSTRACT Introduction Activation of the renin-angiotensin system which is common in diabetes mellitus might affect heme oxygenase (HO-1) gene expression. Aim Assessment of the effects of administration of angiotensin II (Ang II ...
Mohamed Talaat, Abdel Aziz, Mohamed Farid, El Asmer, Taymour, Mostafa, Hazem, Atta, Soheir, Mahfouz, Hanan, Fouad, Laila, Rashed, Dina, Sabry, Amira, Hassouna, Ahmed Talaat, Abdel Aziz, Amira, Senbel, Ahmed, Demery   +11 more
openaire   +2 more sources

Heme and HO-1 Inhibition of HCV, HBV, and HIV [PDF]

Frontiers in Pharmacology, 2012
Hepatitis C virus, human immunodeficiency virus, and hepatitis B virus are chronic viral infections that cause considerable morbidity and mortality throughout the world. In the decades following the identification and sequencing of these viruses, in vitro experiments demonstrated that heme oxygenase-1, its oxidative products, and related compounds of ...
Warren N Schmidt, Warren N Schmidt, Mary M Mathahs, Mary M Mathahs, Zhaowen eZhu, Zhaowen eZhu   +5 more
openaire   +3 more sources

HO-1 expression in human primary prostate tumors. [PDF]

, 2016
(A) Representative sections of HO-1 staining (brown) in non-malignant prostate tissue, in a Gleason score (GS) 7 primary prostate tumor, and in a GS 10 primary prostate tumor (200x magnifications, inserts show higher magnifications).
Emma Jernberg (481248), Pernilla Wikström (175711), Elin Thysell (235940), Sofia Halin Bergström (755313), Maria Nilsson (40527), Hanibal Adamo (2826743), Pär Stattin (124323), Anders Bergh (175717), Anders Widmark (222869)   +8 more
core   +1 more source

Nrf2/HO-1 Axis Regulates the Angiogenesis of Gastric Cancer via Targeting VEGF

Cancer Management and Research, 2021
Yunning Huang,1,* Yuanyuan Yang,2,* Yuanyi Xu,2,* Qian Ma,3,4,* Fengying Guo,2 Yuan Zhao,2 Yuejia Tao,2 Mengqi Li,2 Jiaxin Guo2 1Department of Gastrointestinal Surgery, The Affiliated People’s Hospital of Ningxia Medical University, Yinchuan City ...
Huang Y, Yang Y, Xu Y, Ma Q, Guo F, Zhao Y, Tao Y, Li M, Guo J   +8 more
doaj