Results 51 to 60 of about 465,102 (291)

Relationship between NOX4 level and angiotensin II signaling in Gitelman's syndrome. Implications with hypertension [PDF]

, 2015
Recent evidence showed that endogenous nicotinamide adenine dinucleotide phosphate-oxidase 4 (NOX4) may exert a protective role on the cardiovascular system inducing vasodilation, reduction of blood pressure, and anti-proliferative actions.
Calò, Lorenzo A, Davis, Paul A, Maiolino, Giuseppe, Pagnin, Elisa, Ravarotto, Verdiana, Savoia, Carmine   +5 more
core  

Astaxanthin protects against MPP+-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis [PDF]

, 2012
BACKGROUND: Although the etiology of PD remains unclear, increasing evidence has shown that oxidative stress plays an important role in its pathogenesis and that of other neurodegenerative disorders.
Bixia Huang, Qinyong Ye, Xiaochun Chen, Xiaodong Zhang, Yuangui Zhu   +4 more
core   +1 more source

Heme oxygenase-1 derived carbon monoxide suppresses Aβ1-42 toxicity in astrocytes [PDF]

, 2017
Neurodegeneration in Alzheimer’s disease (AD) is extensively studied, and the involvement of astrocytes and other cell types in this process has been described.
A Almeida, A Verkhratsky, AC LeBlanc, AY Abramov, AY Abramov, AY Abramov, BJ Murphy, C Culmsee, C Culmsee, C Taille, D Aguirre-Rueda, D Lim, D Lim, DE Bredesen, DH Cho, DJ Selkoe, G Esposito, GC Petzold, GT Sutherland, H Ischiropoulos, HJ Luth, HM Schipper, HM Schipper, HM Schipper, IF Smith, J Hardy, J Jacobson, J Qu, J Vina, JA Hardy, JA Hewett, JJ Rodriguez, JJ Rodriguez-Arellano, JL Scragg, JP Bolanos, JX Jiang, K Chen, K Srisook, L Canevari, L Conforti, M Talantova, MC Tomasini, MH Tran, ML Dallas, ML Dallas, ML Dallas, MM Al-Owais, MP Kummer, N Hettiarachchi, N Imuta, NT Hettiarachchi, P Narayan, PD Coleman, PJ Lee, PR Angelova, R Dringen, R Lent, RT Kinobe, T Malinski, T Nakamura, T Nakamura, T Nakamura, TP Misko, V Parpura, V Parpura, V Thorns, W Song, Y Otsu, Z Gu   +68 more
core   +3 more sources

1,3,4, Oxadiazole Compound A3 Provides Robust Protection Against PTZ-Induced Neuroinflammation and Oxidative Stress by Regulating Nrf2-Pathway [Retraction]

Journal of Inflammation Research, 2022
Alvi AM, Shah FA, Muhammad AJ, Feng J, Li S. J Inflamm Res. 2021;14:7393–7409. The Editor and Publisher of Journal of Inflammation Research wish to retract the published article.
Alvi AM, Shah FA, Muhammad AJ, Feng J, Li S   +4 more
doaj  

Scrophularia koraiensis Nakai Attenuates Allergic Airway Inflammation via Suppression of NF-κB and Enhancement of Nrf2/HO-1 Signaling

Antioxidants, 2020
Scrophularia koraiensis Nakai (Scrophulariaceae) is a medicinal herb that grows in Korea and which has been widely used to treat fever, edema, neuritis and laryngitis.
Tae-Yang Jung, A Yeong Lee, Jun-Ho Song, Min Young Lee, Je-Oh Lim, Se-Jin Lee, Je-Won Ko, Na-Rae Shin, Jong-Choon Kim, In-Sik Shin, Joong-Sun Kim   +10 more
doaj   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway [PDF]

, 2016
Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown ...
Botham, K M, Latham Birt, S H, Purcell, R, Wheeler-Jones, C P D   +3 more
core   +1 more source

Flavone improves liver damage in nicotine-exposed rats via the Nrf2/HO-1 pathway

Asian Pacific Journal of Tropical Biomedicine
Objective: To assess the hepatoprotective effects of flavone on nicotine-induced liver damage. Methods: Thirty-six rats were allocated into six groups: the control group, the nicotine group, the flavone alone groups (10 and 25 mg/ kg/body weight), and ...
Nora A. Elsayed, Fatma SM Moawed, Esraa SA Ahmed, Ahmed Hammad, Omayma AR Abo-Zaid   +4 more
doaj   +1 more source

Andrographolide Inhibits Static Mechanical Pressure-Induced Intervertebral Disc Degeneration via the MAPK/Nrf2/HO-1 Pathway

Drug Design, Development and Therapy, 2023
Cunxin Zhang,1,2 Ziang Lu,3 Chaoliang Lyu,2 Shanshan Zhang,4 Dechun Wang1 1Department of Spine Surgery, Qingdao Municipal Hospital, Shandong University, Qingdao, 266061, People’s Republic of China; 2Department of Spine Surgery, Jining No.1 People’s ...
Zhang C, Lu Z, Lyu C, Zhang S, Wang D
doaj  

Novel compound heterozygous stop‐gain mutations of LRBA in a Vietnamese patient with Common Variable Immune Deficiency

Molecular Genetics & Genomic Medicine, 2020
Background Lipopolysaccharide‐responsive and beige‐like anchor (LRBA) deficiency is a rare autosomal recessive common variable immunodeficiency (CVID), affecting 1:25,000–1:50,000 people worldwide.
Anh N. L. Phan, Thuy T. T. Pham, Nghia Huynh, Tuan M. Nguyen, Cuc T. T. Cao, Duong T. Nguyen, Duc T. Le, Chi‐Bao Bui   +7 more
doaj   +1 more source