Results 71 to 80 of about 22,040,645 (295)

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

The Nrf2/HO‐1 Axis in Cancer Cell Growth and Chemoresistance [PDF]

Oxidative Medicine and Cellular Longevity, 2015
The transcription factor, nuclear factor erythroid 2 p45‐related factor 2 (Nrf2), acts as a sensor of oxidative or electrophilic stresses and plays a pivotal role in redox homeostasis. Oxidative or electrophilic agents cause a conformational change in the Nrf2 inhibitory protein Keap1 inducing the nuclear translocation of the transcription factor which,
Furfaro, Annalisa, Traverso, N., Domenicotti, C., Piras, S., Moretta, L., Marinari, U. M., Pronzato, M. A., Nitti, M.   +7 more
openaire   +2 more sources

Asceles albistriatus Ho 2013 [PDF]

, 2016
Asceles albistriatus Ho, 2013 E/T Asceles albistriatus, Ho, 2013a: 821, figs. 1–4. Types. Holotype: ♀, Jianfengling National Nature Reserve, Ledong, Hainan, China, 16.IV.2011, George Ho Wai- Chun (SYSBM); Paratypes: 1♂, Jianfengling ...
Ho, George Wai-Chun
core   +1 more source

DataSheet2_Dao-Chi Powder Ameliorates Pancreatitis-Induced Intestinal and Cardiac Injuries via Regulating the Nrf2-HO-1-HMGB1 Signaling Pathway in Rats.ZIP [PDF]

, 2022
Dao-Chi powder (DCP) has been widely used in the treatment of inflammatory diseases in the clinical practice of traditional Chinese medicine, but has not been used in acute pancreatitis (AP).
Xiajia Wu (5560334), Yue Yang (52715), Qian Hu (205735), Yumei Zhang (415982), Huan Chen (6545), Jiaqi Yao (235055), Yifan Miao (5514839), Lv Zhu (5514845), Meihua Wan (91904), Xiaoyu Dai (4779876), Wenfu Tang (91903)   +10 more
core   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation [PDF]

Antioxidants, 2017
The upregulation of heme oxygenase-1 (HO-1) is one of the most important mechanisms of cell adaptation to stress. Indeed, the redox sensitive transcription factor Nrf2 is the pivotal regulator of HO-1 induction. Through the antioxidant, antiapoptotic, and antinflammatory properties of its metabolic products, HO-1 plays a key role in healthy cells in ...
Nitti, Mariapaola, Piras, Sabrina, Marinari, Umberto M., Moretta, Lorenzo, Pronzato, Maria A., Furfaro, Annalisa   +5 more
openaire   +2 more sources

Dysiarenone from Marine Sponge Dysidea arenaria Attenuates ROS and Inflammation via Inhibition of 5-LOX/NF-κB/MAPKs and Upregulation of Nrf-2/OH-1 in RAW 264.7 Macrophages

Journal of Inflammation Research, 2021
Tian-Yong Hu,1,* Hua Zhang,1,* Yan-Yan Chen,1 Wei-Hua Jiao,2 Jun-Ting Fan,3 Zhi-Qiang Liu,1 Hou-Wen Lin,2 Bao-Hui Cheng1 1Shenzhen Key Laboratory of ENT, Institute of ENT and Longgang ENT Hospital, Shenzhen, 518172, People’s Republic of China ...
Hu TY, Zhang H, Chen YY, Jiao WH, Fan JT, Liu ZQ, Lin HW, Cheng BH   +7 more
doaj  

SYNTHESIS OF FERRITE NANOPARTICLES WITH PROTEIN MOLECULES IMMOBILLIZED ON THEIR SURFACES

ASEAN Journal on Science and Technology for Development, 2017
The ferrite (a Fe3O4 – gFe2O3 mixed solution) fine particles, ~8 nm in size were synthesized from an aqueous solution. Trypsin, a proteolytic enzyme or a protein, was immobilized onto the surfaces of those particles during the synthesis process.
Tran Hoang Hai, Le Hong Phuc, Doan Thi Kim Dung, Nguyen Thi Le Huyen, Bui Duc Long, Nguyen Tien Thang, Vu Van Do, Nguyen Thi Nhu Quynh, Masanori Abe   +8 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Echinacoside alleviates osteoarthritis in rats by activating the Nrf2-HO-1 signaling pathway [PDF]

, 2022
Osteoarthritis (OA) is a progressive disease characterized by degeneration of cartilage and echinacoside (Ech) has anti-inflammatory and antioxidant effects in various human diseases.
Bin Zhang (64682), Zhijun Tan (429568)
core   +1 more source