The Effect of Holder Pasteurization on Nutrients and Biologically-Active Components in Donor Human Milk: A Review [PDF]
When a mother’s milk is unavailable, the best alternative is donor milk (DM). Milk delivered to Human Milk Banks should be pasteurized in order to inactivate the microbial agents that may be present. Currently, pasteurization, performed at 62.5 °C for 30 min (Holder Pasteurization, HoP), is recommended for this purpose in international guidelines ...
Alessandra Coscia +2 more
exaly +6 more sources
Short-chain fatty acids levels in human milk are not affected by holder pasteurization and high hydrostatic pressure processing [PDF]
Sterilized donor milk (DM) is frequently used for feeding preterm infants. To date, the effect of different modes of DM sterilization on short-chain fatty acids (SCFAs) remains unknown.
Lucie Marousez +11 more
doaj +2 more sources
Effects of Holder pasteurization on the protein profile of human milk. [PDF]
The most widespread method for the treatment of donor milk is the Holder pasteurization (HoP). The available literature data show that HoP may cause degradation of some bioactive components. The aim of this study was to determine the effect of HoP on the protein profile of human milk (HM) using a GeLC-MS method, a proteomic approach and a promising ...
Peila C +8 more
europepmc +6 more sources
Impact of Holder Pasteurization on Extracellular Vesicles and Immunoregulatory MicroRNAs in Human Breast Milk. [PDF]
Human breast milk contains bioactive molecules, including microRNAs (miRNAs) that regulate neonatal development and immunity. Pasteurization ensures microbiological safety in milk banks, but its effects on milk-derived miRNAs remain unclear. This study evaluated the impact of Holder pasteurization (62.5 °C, 30 min) on extracellular vesicle (EVs ...
Gómez Martínez C +6 more
europepmc +5 more sources
Microbiological safety and immunoglobulin A retention in bottle-agitated Holder pasteurization of human milk [PDF]
Background National guidelines for donor human milk pasteurization in Peru and most low to middle income countries use Holder Pasteurization (HoP; 62.5 °C, 30 min) and indicate that the bottles containing milk should be agitated manually every 5 min ...
Luis Jimenez +7 more
doaj +2 more sources
Holder pasteurization of donated human milk is effective in inactivating SARS-CoV-2. [PDF]
Provision of pasteurized donor human milk, as a bridge to mother's own milk, is the standard of care for very low-birth-weight infants in hospital. The aim of this research was to confirm that Holder pasteurization (62.5°C for 30 min) would be sufficient to inactivate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in donated human milk ...
Unger S +6 more
europepmc +4 more sources
Effects of Holder Pasteurization on 15-F2t-Isoprostane and Total Antioxidant Power in Donor Human Milk [PDF]
Human milk is the optimal standard for neonatal nutrition, particularly for preterm infants. Several conditions associated with oxidative stress (OS) may be transmitted from mother to infant through milk, making the preservation of milk quality essential.
Valeria Bellisario +7 more
doaj +2 more sources
Loss of antioxidant function in donor human milk after holder pasteurization: a pilot study [PDF]
Human milk is considered the best food for infants. In certain instances, such as feeding premature babies, or babies with diseases requiring hospitalization, donor human milk (DHM) is used where mother's own milk is unavailable.
Andrea Leong +3 more
doaj +2 more sources
Pasteurization Preserves IL-8 in Human Milk [PDF]
Background: Pasteurized donor human milk is an alternative feeding when mothers' own milk is not available for premature infants. The effects of pasteurization on the host defense properties of human milk are unclear.
Marilyn V. Giorgi +4 more
doaj +2 more sources
The Sterilization of Human Milk by Holder Pasteurization or by High Hydrostatic Pressure Processing Leads to Differential Intestinal Effects in Mice [PDF]
Claude Knauf +2 more
exaly +2 more sources

