Results 11 to 20 of about 119,108 (236)

Functions of LIM-homeobox genes

open access: yesTrends in Genetics, 2000
Homeobox genes play fundamental roles in development. They can be subdivided into several subfamilies, one of which is the LIM-homeobox subfamily. The primary structure of LIM-homeobox genes has been remarkably conserved through evolution. Have their functions similarly been conserved?
O, Hobert, H, Westphal
openaire   +4 more sources

Genome-wide analysis of homeobox gene family in legumes: identification, gene duplication and expression profiling. [PDF]

open access: yesPLoS ONE, 2015
Homeobox genes encode transcription factors that are known to play a major role in different aspects of plant growth and development. In the present study, we identified homeobox genes belonging to 14 different classes in five legume species, including ...
Annapurna Bhattacharjee   +3 more
doaj   +1 more source

An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis. [PDF]

open access: yesPLoS ONE, 2015
Here we used predictive gene expression signatures within a multi-species framework to identify the genes that underlie cardiac cell fate decisions in differentiating embryonic stem cells.
Brian W Busser   +5 more
doaj   +1 more source

Homeobox Gene Expression Dysregulation as Potential Diagnostic and Prognostic Biomarkers in Bladder Cancer

open access: yesDiagnostics, 2023
Homeobox genes serve as master regulatory transcription factors that regulate gene expression during embryogenesis. A homeobox gene may have either tumor-promoting or tumor-suppressive properties depending on the specific organ or cell lineage where it ...
Fee-Wai Chin   +2 more
doaj   +1 more source

Classification and nomenclature of all human homeobox genes

open access: yesBMC Biology, 2007
Background The homeobox genes are a large and diverse group of genes, many of which play important roles in the embryonic development of animals. Increasingly, homeobox genes are being compared between genomes in an attempt to understand the evolution of
Bruford Elspeth A   +2 more
doaj   +1 more source

Homeobox genes in normal and abnormal vasculogenesis [PDF]

open access: yes, 2008
Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with ...
Cantile M   +3 more
core   +1 more source

The dynamics of vertebrate homeobox gene evolution: gain and loss of genes in mouse and human lineages

open access: yesBMC Evolutionary Biology, 2011
Background Homeobox genes are a large and diverse group of genes, many of which play important roles in transcriptional regulation during embryonic development.
Holland Peter WH, Zhong Ying-fu
doaj   +1 more source

Human Homeobox TGIFLX Regulates CDX1, CDX2, and OCT1 Genes Expression in Colorectal Cancer Cell Lines [PDF]

open access: yesMiddle East Journal of Cancer, 2022
Background: Homeodomain transcriptional regulatory proteins, which are encoded by Homeobox (HOX) genes, play critical roles in both normal development and carcinogenesis.
Soroosh Shahryarhesami   +3 more
doaj   +1 more source

Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes [PDF]

open access: yes, 2014
This study was funded by the Sars Centre core budget to M. Adamska. Sequencing was performed at the Norwegian High Throughput Sequencing Centre funded by the Norwegian Research Council. O.M.R. and D.E.K.F.
A Saudemont   +27 more
core   +2 more sources

HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer [PDF]

open access: yes, 2017
Homeobox (HOX) genes are conserved transcription factors which determine the anterior-posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several tumors such as lung carcinoma, neuroblastoma, glioma and colorectal cancer (CRC ...
Mansour, Mohammed A., Senga, Takeshi
core   +1 more source

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