Results 41 to 50 of about 1,750,738 (139)

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]

, 2011
The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Glenda J. Dickson, Pamela M. Corrigan, Freeburn, R.W., Robin W. Freeburn, Dickson, Glenda, Thompson, Alexander, Ramsey, Joanne, Helen Wheadon, Wheadon, H., Dickson, G.J., Edwina Dobbin, Alexander Thompson, Ramsey, J.M., Corrigan, P.M., Joanne M. Ramsey, Dobbin, E., Thompson, A.   +16 more
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ERN1 knockdown modifies the hypoxic regulation of homeobox gene expression in U87MG glioblastoma cells

Endocrine Regulations
Homeobox genes play an important role in health and disease including oncogenesis. The present investigation aimed to study ERN1-dependent hypoxic regulation of the expression of genes encoding homeobox proteins MEIS (zinc finger E-box binding homeobox 2)
Krasnytska Daria A., Khita Olena O., Viletska Yuliia M., Minchenko Dmytro O., Halkin Oleh V., Rudnytska Olha V., Hoian Sofiia L., Minchenko Oleksandr H.   +7 more
doaj   +1 more source

Annelid Distal-less/Dlx duplications reveal varied post-duplication fates [PDF]

, 2011
Additional files can be viewed at http://www.biomedcentral.com/1471-2148/11/241/additional/ "Work in the authors’ laboratory is supported by the BBSRC and the School of Biology, University of St Andrews"Background: Dlx (Distal-less) genes have various ...
Natalia Korchagina, Jonathan L Tobin, Ferrier, David E.K., Tobin, Jonathan L., McDougall, Carmel, McDougall Carmel, Ferrier, David EK, Carmel McDougall, Korchagina, Natalia, David EK Ferrier, Tobin Jonathan L, Tobin, Johnathan, Ferrier, David Ellard Keith, Ferrier David EK, Ferrier, David E. K., Tobin, Jonathan L, Korchagina Natalia   +16 more
core   +2 more sources

NKL homeobox gene activities in B-cell development and lymphomas. [PDF]

PLoS ONE, 2018
Homeobox genes encode transcription factors which regulate basic processes in development and cell differentiation. Several members of the NKL subclass are deregulated in T-cell progenitors and support leukemogenesis.
Stefan Nagel, Roderick A F MacLeod, Corinna Meyer, Maren Kaufmann, Hans G Drexler   +4 more
doaj   +1 more source

Single Rooted Permanent Premolars and Molars - A Rare Clinical Presentation Confirmed using Cone Beam Computed Tomography [PDF]

Journal of Clinical and Diagnostic Research, 2015
The morphology of the root and root canal system plays a significant role in the treatment outcome of endodontic procedures. The necessity of clear and high contrast images for tissues like bone and teeth has made the usage of newer imaging techniques ...
Nadeem Jeddy, T. Radhika, S. Nithya, C. Krithika, Ramachandra Prabakar   +4 more
doaj   +1 more source

The homeobox genes of Encephalitozoon cuniculi (Microsporidia) reveal a putative mating-type locus

, 2003
Homeobox genes have been found in animals, fungi, and plants. Recently, the complete genomic sequence of Encephalitozoon cuniculi has become available and it was shown that this Microsporida species is related to fungi.
Bürglin, TR, Burglin, Thomas R,
core   +1 more source

Homeobox and Polycomb target gene methylation in human solid tumors

Scientific Reports
DNA methylation is an epigenetic mark that plays an important role in defining cancer phenotypes, with global hypomethylation and focal hypermethylation at CpG islands observed in tumors. These methylation marks can also be used to define tumor types and
Reid Blanchett, Kin H. Lau, Gerd P. Pfeifer   +2 more
doaj   +1 more source

Characterization of the Proteins HPIP and VENTX2 as Novel Regulatory Proteins of Human Hematopoiesis [PDF]

, 2006
The hallmark of hematopoietic stem cells (HSC) is their ability of self-renewal and differentiation into multiple hematopoietic cell lineages. Although the molecular network controlling stem cell fate decisions is largely unknown, multiple studies have ...
Arseni, Natalia, Arseni, N.
core   +1 more source

Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation

Scientific Reports, 2017
Homeobox genes regulate embryonic and placental development, and are widely expressed in the human placenta, but their regulatory control by DNA methylation is unclear.
Boris Novakovic, Thierry Fournier, Lynda K. Harris, Joanna James, Claire T. Roberts, Hannah E. J. Yong, Bill Kalionis, Danièle Evain-Brion, Peter R. Ebeling, Euan M. Wallace, Richard Saffery, Padma Murthi   +11 more
doaj   +1 more source

"Developmental studies of the murine homeobox gene - hoxa-9” [PDF]

, 2002
Cell patterning during embryogenesis is essential for establishing the identity of the developing body plan. Hox genes are fundamental regulators of tissue organisation along the anterior-posterior body axis of the developing embryo.
Lincoln, Joy
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