Results 31 to 40 of about 1,750,738 (139)

ERN1 knockdown modifies the effect of glucose deprivation on homeobox gene expressions in U87 glioma cells

Endocrine Regulations, 2020
Objective. The aim of the present investigation was to study the expression of genes encoding homeobox proteins ZEB2 (zinc finger E-box binding homeobox 2), TGIF1 (TGFB induced factor homeobox 1), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1),
Tsymbal Dariia O., Minchenko Dmytro O., Khita Olena O., Rudnytska Olha V., Viletska Yulia M., Lahanovska Yulia O., He Qiuxia, Liu Kechun, Minchenko Oleksandr H.   +8 more
doaj   +1 more source

Aberrant activity of NKL homeobox gene NKX3-2 in a T-ALL subset. [PDF]

PLoS ONE, 2018
T-cell acute lymphoblastic leukemia (T-ALL) is a hematopoietic malignancy originating from T-cell progenitors in which differentiation is blocked at early stages.
Stefan Nagel, Corinna Meyer, Maren Kaufmann, Margarete Zaborski, Roderick A F MacLeod, Hans G Drexler   +5 more
doaj   +1 more source

Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes [PDF]

, 2009
Background The ParaHox gene cluster is the evolutionary sister to the Hox cluster. Whilst the role of the Hox cluster in patterning the anterior-posterior axis of bilaterian animals is well established, and the organisation of vertebrate Hox clusters is ...
Segurens Béatrice, Segurens, B, Jubin Claire, Balavoine, Guillaume, Hui, J. H L, Raible, Florian, Jubin, Claire, Hui, JHL, Arendt, Detlev, Ferrier, David E K, Dray, N, Segurens, Béatrice, Samain, Sylvie (Génoscope, Centre National de Séquençage), Samain, S, Samain Sylvie, Magdelenat, Ghislaine, Balavoine Guillaume, Korchagina, Natalia, Ferrier, D. E K, Raible, F, Jubin, C, Hui, Jerome (University of Oxford), Ferrier David EK, Samain, Sylvie, Arendt, Detlev (Developmental Biology Unit), Korchagina, Natalia (University of Oxford), Arendt, D, Arendt Detlev, Segurens, Béatrice (Génoscope, Centre National de Séquençage), Raible Florian, Balavoine, G, Magdelenat Ghislaine, Korchagina, N, Dray, Nicolas (Centre National de la Recherche Scientifique (CNRS)), Balavoine, Guillaume (Institut Jacques Monod), Dray Nicolas, Magdelenat, Ghislaine (Génoscope, Centre National de Séquençage), Jubin, Claire (Génoscope, Centre National de Séquençage), Hui Jerome HL, Ferrier, David E.K. (The Gatty Marine Laboratory), Hui, Jerome H L, Raible, Florian (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Dray, Nicolas, Hui, Jerome, Ferrier, David Ellard Keith, Magdelenat, G, Korchagina Natalia   +46 more
core   +1 more source

NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia.

PLoS ONE, 2017
T-cell acute lymphoblastic leukemia (T-ALL) cells represent developmentally arrested T-cell progenitors, subsets of which aberrantly express homeobox genes of the NKL subclass, including TLX1, TLX3, NKX2-1, NKX2-5, NKX3-1 and MSX1.
Stefan Nagel, Claudia Pommerenke, Michaela Scherr, Corinna Meyer, Maren Kaufmann, Karin Battmer, Roderick A F MacLeod, Hans G Drexler   +7 more
doaj   +1 more source

Transcriptional activation of prostate specific homeobox gene NKX3-1 in subsets of T-cell lymphoblastic leukemia (T-ALL). [PDF]

PLoS ONE, 2012
Homeobox genes encode transcription factors impacting key developmental processes including embryogenesis, organogenesis, and cell differentiation. Reflecting their tight transcriptional control, homeobox genes are often embedded in large non-coding, cis-
Stefan Nagel, Stefan Ehrentraut, Jürgen Tomasch, Stefan Lienenklaus, Björn Schneider, Robert Geffers, Corinna Meyer, Maren Kaufmann, Hans G Drexler, Roderick A F MacLeod   +9 more
doaj   +1 more source

Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain [PDF]

, 2007
The homeobox gene Hesx1 is an essential repressor that is required within the anterior neural plate for normal forebrain development in mouse and humans. Combining genetic cell labelling and marker analyses, we demonstrate that the absence of Hesx1 leads
Andoniadou, CL, Sajedi, E, Itasaki, Nobue, Andoniadou, Cynthia L; id_orcid, Mehul Dattani, Kelberman, D, Martinez-Barbera, Juan Pedro, Juan Pedro Martinez-Barbera, Ezat Sajedi, Dattani, Mehul, Daniel Kelberman, Carles Gaston-Massuet, Martinez-Barbera, JP, Kelberman, Daniel, Signore, M, Dattani, M, Burns, Alan J, Signore, Massimo, Andoniadou, Cynthia L, Nobue Itasaki, Sajedi, Ezat, Cynthia L. Andoniadou, Gaston-Massuet, Carles, Burns, AJ, Itasaki, N, Alan J. Burns, Massimo Signore, Gaston-Massuet, C   +27 more
core   +1 more source

The Aspergillus flavus Homeobox Gene, hbx1, Is Required for Development and Aflatoxin Production

Toxins, 2017
Homeobox proteins, a class of well conserved transcription factors, regulate the expression of targeted genes, especially those involved in development.
Jeffrey W. Cary, Pamela Harris-Coward, Leslie Scharfenstein, Brian M. Mack, Perng-Kuang Chang, Qijian Wei, Matthew Lebar, Carol Carter-Wientjes, Rajtilak Majumdar, Chandrani Mitra, Sourav Banerjee, Anindya Chanda   +11 more
doaj   +1 more source

NK2 homeobox gene cluster: Functions and roles in human diseases

Genes and Diseases, 2023
NK2 genes (NKX2 gene cluster in humans) encode for homeodomain-containing transcription factors that are conserved along the phylogeny. According to the most detailed classifications, vertebrate NKX2 genes are classified into two distinct families, NK2.1
Catia Mio, Federica Baldan, Giuseppe Damante   +2 more
doaj   +1 more source

Characterization of Rice Homeobox Genes, OsHOX22 and OsHOX24, and Over-expression of OsHOX24 in Transgenic Arabidopsis Suggest their Role in Abiotic Stress Response

Frontiers in Plant Science, 2016
Homeobox transcription factors are well known regulators of plant growth and development. In this study, we carried out functional analysis of two candidate stress-responsive HD-ZIP I class homeobox genes from rice, OsHOX22 and OsHOX24.
Annapurna eBhattacharjee, Jitendra Paul Khurana, Mukesh eJain, Mukesh eJain   +3 more
doaj   +1 more source

Rs868058 in the Homeobox Gene HLX Contributes to Early-Onset Fetal Growth Restriction

Biology, 2022
Fetal growth restriction (FGR) is a condition that characterizes fetuses as too small for their gestational age, with an estimated fetal weight (EFW) below the 10th percentile and abnormal Doppler parameters and/or with EFW below the 3rd percentile.
Wioletta Izabela Wujcicka, Marian Kacerovsky, Michał Krekora, Piotr Kaczmarek, Beata Leśniczak, Mariusz Grzesiak   +5 more
doaj   +1 more source