Results 31 to 40 of about 119,960 (296)
Thyroid-specific transcription factors control Hex promoter activity [PDF]
, 2003 The homeobox-containing gene Hex is expressed in several cell types, including thyroid follicular cells, in which it regulates the transcription of tissue-specific genes. In this study the regulation of Hex promoter activity was investigated.
A. V., D'Elia +9 more
core +1 more source
The molecular basis of T cell acute lymphoblastic leukemia [PDF]
, 2012 T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando +23 more
core +1 more source
Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes [PDF]
, 2014 This study was funded by the Sars Centre core budget to M. Adamska. Sequencing was performed at the Norwegian High Throughput Sequencing Centre funded by the Norwegian Research Council. O.M.R. and D.E.K.F.
A Saudemont +27 more
core +2 more sources
Congenital absence of the left thumb in a surviving twin - a genetic disorder
National Journal of Clinical Anatomy, 2014 Congenital absence of left thumb with deformities of carpal bones in a twin born adult woman is reported here. The subject is the only surviving twin aged forty years reported to the hospital with a complaint of weakness of left hand.
D N Sinha
doaj +1 more source
Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate. [PDF]
PLoS ONE, 2012 Among gene families it is the Hox genes and among metazoan animals it is the insects (Hexapoda) that have attracted particular attention for studying the evolution of development.
Heike Hadrys +6 more
doaj +1 more source
HLXB9 gene expression, and nuclear location during in vitro neuronal differentiation in the SK-N-BE neuroblastoma cell line [PDF]
, 2014 Copyright @ 2014 Leotta et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Brundo, MV +4 more
core +1 more source
Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma.
PLoS ONE, 2021 Homeobox genes encode transcription factors which regulate basic processes in development and cell differentiation and are grouped into classes and subclasses according to sequence similarities.
Stefan Nagel +4 more
doaj +1 more source
Optimal activation of an endogenous gene by HOX11 requires the NH 2- terminal 50 amine acids [PDF]
, 1998 The HOX11 homeobox gene was first identified through studies of the t(7;10) and t(10;14) chromosomal translocations of acute T-cell leukemia. In addition, analysis of Hox11(-/-) mice has demonstrated a critical role for this gene in murine spleen ...
Masson, N., Greene, W.K., Rabbitts, T.H.
core +2 more sources
F1000Research, 2018 The homeodomain-containing proteins are an important group of transcription factors found in most eukaryotes including animals, plants and fungi. Homeobox genes are responsible for a wide range of critical developmental and physiological processes ...
Wai Hoong Chang, Alvina G. Lai
doaj +1 more source
Endocrine Regulations, 2020 Objective. The aim of the present investigation was to study the expression of genes encoding homeobox proteins ZEB2 (zinc finger E-box binding homeobox 2), TGIF1 (TGFB induced factor homeobox 1), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1),
Tsymbal Dariia O. +8 more
doaj +1 more source