Homeobox Genes and Hepatocellular Carcinoma. [PDF]
Cancers (Basel), 2019 Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, and is the third leading cause of cancer-related deaths each year. It involves a multi-step progression and is strongly associated with chronic inflammation induced by the intake of environmental toxins and/or viral infections (i.e., hepatitis B and C viruses).
Liu KY, Wang LT, Hsu SH, Wang SN.
europepmc +4 more sources
The Homeobox Genes of Caenorhabditis elegans and Insights into Their Spatio-Temporal Expression Dynamics during Embryogenesis. [PDF]
PLoS ONE, 2015 Homeobox genes play crucial roles for the development of multicellular eukaryotes. We have generated a revised list of all homeobox genes for Caenorhabditis elegans and provide a nomenclature for the previously unnamed ones.
Jürgen Hench +10 more
doaj +1 more source
Genome-wide analysis of homeobox gene family in legumes: identification, gene duplication and expression profiling. [PDF]
PLoS ONE, 2015 Homeobox genes encode transcription factors that are known to play a major role in different aspects of plant growth and development. In the present study, we identified homeobox genes belonging to 14 different classes in five legume species, including ...
Annapurna Bhattacharjee +3 more
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An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis. [PDF]
PLoS ONE, 2015 Here we used predictive gene expression signatures within a multi-species framework to identify the genes that underlie cardiac cell fate decisions in differentiating embryonic stem cells.
Brian W Busser +5 more
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Diagnostics, 2023 Homeobox genes serve as master regulatory transcription factors that regulate gene expression during embryogenesis. A homeobox gene may have either tumor-promoting or tumor-suppressive properties depending on the specific organ or cell lineage where it ...
Fee-Wai Chin +2 more
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Classification and nomenclature of all human homeobox genes
BMC Biology, 2007 Background The homeobox genes are a large and diverse group of genes, many of which play important roles in the embryonic development of animals. Increasingly, homeobox genes are being compared between genomes in an attempt to understand the evolution of
Bruford Elspeth A +2 more
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BMC Evolutionary Biology, 2011 Background Homeobox genes are a large and diverse group of genes, many of which play important roles in transcriptional regulation during embryonic development.
Holland Peter WH, Zhong Ying-fu
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HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer [PDF]
, 2017 Homeobox (HOX) genes are conserved transcription factors which determine the anterior-posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several tumors such as lung carcinoma, neuroblastoma, glioma and colorectal cancer (CRC ...
Mansour, Mohammed A., Senga, Takeshi
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Human Homeobox TGIFLX Regulates CDX1, CDX2, and OCT1 Genes Expression in Colorectal Cancer Cell Lines [PDF]
Middle East Journal of Cancer, 2022 Background: Homeodomain transcriptional regulatory proteins, which are encoded by Homeobox (HOX) genes, play critical roles in both normal development and carcinogenesis.
Soroosh Shahryarhesami +3 more
doaj +1 more source
NaNog: A pluripotency homeobox (master) molecule. [PDF]
, 2015 One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE +4 more
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