Results 21 to 30 of about 119,960 (296)
Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]
, 2011 The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Alexander Thompson +10 more
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Diversity, phylogeny and expression patterns of Pou and Six homeodomain transcription factors in hydrozoan jellyfish Craspedacusta sowerbyi. [PDF]
PLoS ONE, 2012 Formation of all metazoan bodies is controlled by a group of selector genes including homeobox genes, highly conserved across the entire animal kingdom.
Miluse Hroudova +7 more
doaj +1 more source
Endocrine Regulations, 2022 Objective. The aim of the current study was to investigate the expression of genes encoded homeobox proteins such as MEIS3 (Meis homeobox 3), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1), LHX2, and LHX6 in U87 glioma cells in response to ...
Krasnytska Dariia A. +7 more
doaj +1 more source
NKL homeobox gene activities in normal and malignant myeloid cells.
PLoS ONE, 2019 Recently, we have documented a hematopoietic NKL-code mapping physiological expression patterns of NKL homeobox genes in early hematopoiesis and in lymphopoiesis, which spotlights genes deregulated in lymphoid malignancies.
Stefan Nagel +8 more
doaj +1 more source
Identification and characterization of homeobox genes in Eucalyptus
Genetics and Molecular Biology, 2005 Homeobox genes encode transcriptional factors, usually involved in molecular control of plant developmental patterns. They can be divided into several classes according to conserved sequences within the homeobox region and the presence of specific ...
Graça Celeste Gomes Rocha +4 more
doaj +1 more source
The C. elegans LIM homeobox gene lin-11 specifies multiple cell fates during vulval development [PDF]
, 2003 LIM homeobox family members regulate a variety of cell fate choices during animal development. In C. elegans, mutations in the LIM homeobox gene lin-11 have previously been shown to alter the cell division pattern of a subset of the 2° lineage vulval ...
Gupta, Bhagwati P. +2 more
core +1 more source
BMC Genomics, 2020 Background Homeobox-containing genes encode crucial transcription factors involved in animal, plant and fungal development, and changes to homeobox genes have been linked to the evolution of novel body plans and morphologies.
Yiqian Li +7 more
doaj +1 more source
Frontiers in Pharmacology, 2014 Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, as well as for their maintenance in the adult. Homeobox genes comprise an important family of transcription factors, which are characterised by a well ...
Padma eMurthi +5 more
doaj +1 more source
Modelling the evolution of transcription factor binding preferences in complex eukaryotes [PDF]
, 2017 Transcription factors (TFs) exert their regulatory action by binding to DNA with specific sequence preferences. However, different TFs can partially share their binding sequences due to their common evolutionary origin.
Caselle, Michele +3 more
core +2 more sources
The T-cell oncogenic protein HOX11 activates Aldh1 expression in NIH 3T3 cells but represses its expression in mouse spleen development [PDF]
, 1998 Hox11 is a homeobox gene essential for spleen formation in mice, since atrophy of the anlage of a developing spleen occurs in early embryonic development in Hox11 null mice.
Greene, W.K. +3 more
core +2 more sources