Results 31 to 40 of about 4,368,468 (230)

Understanding Metabolic Regulation Between Host and Pathogens: New Opportunities for the Development of Improved Therapeutic Strategies Against Mycobacterium tuberculosis Infection

Frontiers in Cellular and Infection Microbiology, 2021
Mycobacterium tuberculosis (Mtb) causes chronic granulomatous lung disease in humans. Recently, novel strategies such as host-directed therapeutics and adjunctive therapies that enhance the effect of existing antibiotics have emerged to better control ...
Ji-Hae Park, Dahee Shim, Keu Eun San Kim, Wonsik Lee, Sung Jae Shin   +4 more
doaj   +1 more source

Host-directed therapies for infectious diseases : current status, recent progress, and future prospects

, 2016
Despite extensive global efforts in the fight against killer infectious diseases, they still cause one in four deaths worldwide and are important causes of long-term functional disability arising from tissue damage.
Rao, M., Rustomjee, R, Yeboah-Manu, Dorothy, Azhar, E., Rao, M,, Zumla, A, Kaufmann, Stefan H. E., Yeboah-Manu, D., Hoelscher, M., Vilaplana, Cris, Mwaba, P., Hoelscher, Michael, Wallis, RS, Mwaba, P, Chakaya, J, Kaufmann, SH, Host-Directed Therapies Network consortium,, Azhar, E, Ippolito, G, Maeurer, Markus, Wallis, Robert S., Zumla, A., Maeurer, M, Rao, Martin, Ippolito, Giuseppe, Hoelscher, M, Chakaya, Jeremiah, Rustomjee, Roxana, Chakaya, J., Ippolito, G., Rao, M, Zumla, Alimuddin, Kaufmann, SHE, Maeurer, M., Rustomjee, R., Vilaplana, C., Vilaplana, C, Kaufmann, S., Mwaba, Peter, Host-Directed Therapies Network consortium, Wallis, R., Azhar, Esam, Yeboah-Manu, D   +42 more
core   +1 more source

Children’s Mental Health Task 11 FY 2007: Family-Directed Structural Therapy Training [PDF]

, 2007
Family-Directed Structural Therapy (FDST) is a family-based helping modality that is designed to be utilized with a variety of family and relationship issues.
McLendon, Tara, McLendon, Don, Petr, Chris   +2 more
core   +1 more source

Combinatorial functions of two chimeric antibodies directed to human CD4 and one directed to the a-chain of the human interleukin-2 receptor [PDF]

, 1992
The general feasibility of chimerization of monoclonal antibodies (mAbs) has already been shown for a large number of them. In order to evaluate in vitro parameters relevant to immunosuppressive therapy, we have chimerized and synthesized two anti-CD4 ...
Schwirzke, Marina, Kaluzab, Brigitte, Reiter, Christian, Rieber, Ernst Peter, Scheuer, Werner, Flieger, Dimitri, Lenz, Helmut, Weissenhorn, Winfried, Weiss, Elisabeth H., Weidle, Ulrich H., Riethmüller, Gert   +10 more
core   +1 more source

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Visceral leishmaniasis (VL) is associated with treatment complications due to the continued growth of resistant parasites toward currently available pathogen-directed therapeutics.
M. Shamim Hasan Zahid, Monica M. Johnson, Robert J. Tokarski, II, Abhay R. Satoskar, James R. Fuchs, Eric M. Bachelder, Kristy M. Ainslie   +6 more
doaj   +1 more source

Bazedoxifene Suppresses Intracellular Mycobacterium tuberculosis Growth by Enhancing Autophagy

mSphere, 2020
Tuberculosis (TB) is still the leading killer caused by Mycobacterium tuberculosis infection. There is a clear need for new treatment strategy against TB.
Qi Ouyang, Kehong Zhang, Dachuan Lin, Carl G. Feng, Yi Cai, Xinchun Chen   +5 more
doaj   +1 more source

Children’s Mental Health Task 11 FY ‘08: Family-Directed Structural Therapy Training and Evaluation Project [PDF]

, 2008
Family-Directed Structural Therapy (FDST) is a family-based helping modality that is designed to be utilized with a variety of family and relationship issues.
McLendon, Tara, McLendon, Don, Petr, Chris, Radohl, Tami   +3 more
core   +1 more source

Can We Harness Immune Responses to Improve Drug Treatment in Leishmaniasis?

Microorganisms, 2020
Leishmaniasis is a vector-borne parasitic disease that has been neglected in priority for control and eradication of malaria, tuberculosis, and HIV/AIDS.
Raphael Taiwo Aruleba, Katharine C. Carter, Frank Brombacher, Ramona Hurdayal   +3 more
doaj   +1 more source

Self-directed multimodal learning in higher education [PDF]

, 2020
This book aims to provide an overview of theoretical and practical considerations in terms of self-directed multimodal learning within the university context.
Bailey, Roxanne, SEELETSO, MMABALEDI, Mentz, Elsa, Kruger, Donnavan, Van der Westhuizen, Christo, Elsie, Lubbe, Laubscher, Dorothy, Olivier, Jako, Bosch, Chantelle, Kruger, Cornè   +9 more
core   +1 more source

Metformin Increases Cell Viability and Regulates Pro-Inflammatory Response to Mtb

Infection and Drug Resistance, 2023
Nikita Naicker,1 Hylton Rodel,2 Rubeshan Perumal,1 Yashica Ganga,2 Mallory Bernstein,2 Ntombi Benede,2 Salim Abdool Karim,1,3 Nesri Padayacthi,1,3 Alex Sigal,2,4,5 Kogieleum Naidoo1,3 1Centre for the AIDS Programme of Research in South Africa (CAPRISA ...
Naicker N, Rodel H, Perumal R, Ganga Y, Bernstein M, Benede N, Abdool Karim S, Padayacthi N, Sigal A, Naidoo K   +9 more
doaj