Results 111 to 120 of about 7,043,725 (272)

Data_Sheet_1_Host-Induced Gene Silencing of a Multifunction Gene Sscnd1 Enhances Plant Resistance Against Sclerotinia sclerotiorum.ZIP

, 2021
Sclerotinia sclerotiorum is a devastating necrotrophic fungal pathogen and has a substantial economic impact on crop production worldwide. Magnaporthe appressoria-specific (MAS) proteins have been suggested to be involved in the appressorium formation in
Yijuan Ding (9450391), Yangui Chen (4904050), Mengquan Dong (11537533), Hongmei Liao (10683897), Xinran Meng (11537536), Baoqin Yan (9450397), Huafang Wan (5530724), Wei Qian (56612)   +7 more
core   +1 more source

Tombusvirus P19-Mediated Suppression of Virus-Induced Gene Silencing Is Controlled by Genetic and Dosage Features That Influence Pathogenicity

Molecular Plant-Microbe Interactions, 2002
The p19 protein (P19) of Tomato bushy stunt virus (TBSV) is a pathogenicity determinant with host-dependent effects on virus spread and symptom induction.
Wenping Qiu, Jong-Won Park, Herman B. Scholthof   +2 more
doaj   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Transient Posttranscriptional Gene Silencing in Medicago truncatula:Virus-Induced Gene Silencing (VIGS)

, 2018
Successful application of virus-induced gene silencing for functional genomics requires a virus vector that can initiate a systemic infection of the host plant.
Joanna Serwatowska, Ida Elisabeth Johansen, Lund, Ole Søgaard, Ole Søgaard Lund, Serwatowska, Joanna, Johansen, Ida Elisabeth   +5 more
core   +1 more source

Cross-Kingdom Small RNAs among Animals, Plants and Microbes

Cells, 2019
Small RNAs (sRNAs), a class of regulatory non-coding RNAs around 20~30-nt long, including small interfering RNAs (siRNAs) and microRNAs (miRNAs), are critical regulators of gene expression.
Jun Zeng, Vijai Kumar Gupta, Yueming Jiang, Bao Yang, Liang Gong, Hong Zhu   +5 more
doaj   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]

, 2014
The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
core   +1 more source

Host-induced gene silencing of the Verticillium dahliae thiamine transporter protein gene (VdThit) confers resistance to Verticillium wilt in cotton

Journal of Integrative Agriculture
Verticillium wilt (VW), induced by the soil-borne fungus Verticillium dahliae (Vd), poses a substantial threat to a diverse array of plant species. Employing molecular breeding technology for the development of cotton varieties with heightened resistance
Qi Wang, Guoqiang Pan, Xingfen Wang, Zhengwen Sun, Huiming Guo, Xiaofeng Su, Hongmei Cheng   +6 more
doaj   +1 more source

Small RNA Regulators of Plant-Hemipteran Interactions: Micromanagers with Versatile Roles

Frontiers in Plant Science, 2016
Non-coding small RNAs (sRNAs) in plants have important roles in regulating biological processes, including development, reproduction, and stress responses.
Sampurna Sattar, Gary A Thompson
doaj   +1 more source

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

Advanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang, Liang Qiu, Xingbang Ruan, Yihan Shi, Ye Wang, Hanwen Li, Kai Zhang, Kangwu Chen   +7 more
wiley   +1 more source