Results 91 to 100 of about 713,544 (377)

Proteogenomics in aid of host-pathogen interaction studies : a bacterial perspective [PDF]

open access: yes, 2017
By providing useful tools to study host-pathogen interactions, next-generation omics has recently enabled the study of gene expression changes in both pathogen and infected host simultaneously.
Fels, Ursula   +2 more
core   +3 more sources

Deconstructing host-pathogen interactions inDrosophila [PDF]

open access: yesDisease Models & Mechanisms, 2012
Many of the cellular mechanisms underlying host responses to pathogens have been well conserved during evolution. As a result, Drosophila can be used to deconstruct many of the key events in host-pathogen interactions by using a wealth of well-developed molecular and genetic tools.
Ethan Bier, Annabel Guichard
openaire   +4 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation

open access: yeseLife, 2018
The intracellular parasite Toxoplasma gondii, hijacks evolutionarily conserved host processes by delivering effector proteins into the host cell that shift gene expression in a timely fashion.
Huan He   +8 more
doaj   +1 more source

Modulation of Cystatin F in Human Macrophages Impacts Cathepsin-Driven Killing of Multidrug-Resistant Mycobacterium tuberculosis

open access: yesMicroorganisms, 2023
Tuberculosis (TB) treatment relies primarily on 70-year-old drugs, and prophylaxis suffers from the lack of an effective vaccine. Among the 10 million people exhibiting disease symptoms yearly, 450,000 have multidrug or extensively drug-resistant (MDR or
Manoj Mandal   +4 more
doaj   +1 more source

Transcript Profiling in Host–Pathogen Interactions [PDF]

open access: yes, 2007
Using genomic technologies, it is now possible to address research hypotheses in the context of entire developmental or biochemical pathways, gene networks, and chromosomal location of relevant genes and their inferred evolutionary history.
Bogdanove, Adam   +4 more
core   +3 more sources

Spatial organization and interactions of harvester ants during foraging activity [PDF]

open access: yes, 2017
Local interactions, when individuals meet, can regulate collective behavior. In a system without any central control, the rate of interaction may depend simply on how the individuals move around. But interactions could in turn influence movement; individuals might seek out interactions, or their movement in response to interaction could influence ...
arxiv   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

Hippo signaling pathway regulates Ebola virus transcription and egress

open access: yesNature Communications
Filovirus-host interactions play important roles in all stages of the virus lifecycle. Here, we identify LATS1/2 kinases and YAP, key components of the Hippo pathway, as critical regulators of EBOV transcription and egress.
Jingjing Liang   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy