Results 51 to 60 of about 803,197 (352)

Toxoplasma effectors targeting host signaling and transcription [PDF]

, 2017
Early electron microscopy studies revealed the elaborate cellular features that define the unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) organelles and small, dense granules (GRAs), both of which are secreted during
Ajioka JA, Andrisani OM, Carruthers VB, Ceravolo IP, Deckert-Schlüter M, Dubey JP, Frenkel JK, Frenkel JK, Gazzinelli R, Gazzinelli RT, Gazzinelli RT, Goebel S, Honoré S, Levine ND, Luder CG, McCabe RE, McLeod R, McLeod R, Morisaki JH, Nash PB, Pfaff AW, Scharton-Kersten TM, Were SR, Yap GS   +23 more
core   +2 more sources

The roles of GpsB and DivIVA in Staphylococcus aureus growth and division

Frontiers in Microbiology, 2023
The spheroid bacterium Staphylococcus aureus is often used as a model of morphogenesis due to its apparently simple cell cycle. S. aureus has many cell division proteins that are conserved across bacteria alluding to common functions.
Joshua A. F. Sutton, Joshua A. F. Sutton, Mark Cooke, Mariana Tinajero-Trejo, Mariana Tinajero-Trejo, Katarzyna Wacnik, Katarzyna Wacnik, Bartłomiej Salamaga, Bartłomiej Salamaga, Callum Portman-Ross, Callum Portman-Ross, Victoria A. Lund, Victoria A. Lund, Jamie K. Hobbs, Jamie K. Hobbs, Simon J. Foster, Simon J. Foster   +16 more
doaj   +1 more source

The role of effectors in nonhost resistance to filamentous plant pathogens [PDF]

, 2014
In nature, most plants are resistant to a wide range of phytopathogens. However, mechanisms contributing to this so-called nonhost resistance (NHR) are poorly understood.
Aghnoum, Antonovics, Arabidopsis Genome Initiative, Baxter, Bolton, Brunner, Chen, de Jonge, de Jonge, de Wit, Dean, Dong, Elmore, Fan, Fradin, Fry, Gilroy, Gladieux, Haas, Hacquard, Jafary, Jeuken, Jones, Jupe, Jupe, Kang, Karasov, Kaschani, King, Kombrink, Lapin, Lee, Levesque, Lozano-Torres, Ma, Maekawa, Meyers, Mondragon-Palomino, Monosi, Morris, Mueller, Niks, Palloix, Pavan, Pedersen, Porter, Qutob, Raffaele, Raffaele, Raffaele, Rice Genome Project, Rouxel, Ruan, Saunders, Schulze-Lefert, Schweizer, Segretin, Shabab, Shan, Shen, Shindo, Spanu, Stam, Stassen, Stassen, Stirnweis, Stukenbrock, Stukenbrock, Stuttmann, Sweigard, Sørensen, Tian, Tosa, Uma, van Schie, Vega-Arreguín, Vogel, Wawra, Win, Wulff, Zellerhoff, Zhang, Zheng, Zipfel   +83 more
core   +5 more sources

Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen

Nature Communications, 2020
Studying emerging or neglected pathogens is often challenging due to insufficient information and absence of genetic tools. Dual RNA-seq provides insights into host-pathogen interactions, and is particularly informative for intracellular organisms.
Bozena Mika-Gospodorz, Suparat Giengkam, A. Westermann, J. Wongsantichon, Willow B. Kion-Crosby, Suthida Chuenklin, Loo Chien Wang, P. Sunyakumthorn, R. Sobota, S. Subbian, J. Vogel, Lars Barquist, J. Salje   +12 more
semanticscholar   +1 more source

Host-pathogen interactions in invasive Staphylococcus aureus infections [PDF]

, 2016
Staphylococcus aureus is a versatile human pathogen causing a wide range of diseases from uncomplicated skin and soft tissue infections to life-threatening invasive diseases like endocarditis, bacteremia, necrotizing pneumonia, and fasciitis.
Mairpady Shambat, Srikanth
core   +1 more source

A new tractable method for generating human alveolar macrophage-like cells in vitro to study lung inflammatory processes and diseases

mBio, 2023
Alveolar macrophages (AMs) are unique lung resident cells that contact airborne pathogens and environmental particulates. The contribution of human AMs (HAMs) to pulmonary diseases remains poorly understood due to the difficulty in accessing them from ...
Susanta Pahari, Eusondia Arnett, Jan Simper, Abul Azad, Israel Guerrero-Arguero, Chengjin Ye, Hao Zhang, Hong Cai, Yufeng Wang, Zhao Lai, Natalie Jarvis, Miranda Lumbreras, Diego Jose Maselli, Jay Peters, Jordi B. Torrelles, Luis Martinez-Sobrido, Larry S. Schlesinger   +16 more
doaj   +1 more source

Tuberculosis in an Aging World

Pathogens, 2022
Tuberculosis (TB) is one of the leading causes of death due to its being an infectious disease, caused by the airborne pathogen Mycobacterium tuberculosis (M.tb).
Angélica M. Olmo-Fontánez, Joanne Turner   +1 more
doaj   +1 more source

Stochastic spatial models of host-pathogen and host-mutualist interactions I

, 2006
Mutualists and pathogens, collectively called symbionts, are ubiquitous in plant communities. While some symbionts are highly host-specific, others associate with multiple hosts.
Lanchier, N., Neuhauser, C.
core   +2 more sources

Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli [PDF]

, 2018
Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination.
Achcar, Fiona, Barrett, Michael P., Goodyear, Carl S., Pountain, Andrew W., Rattigan, Kevin M., Regnault, Clement, Vincent, Isabel M.   +6 more
core   +3 more sources

Artificial intelligence and neoantigens: paving the path for precision cancer immunotherapy

Frontiers in Immunology
Cancer immunotherapy has witnessed rapid advancement in recent years, with a particular focus on neoantigens as promising targets for personalized treatments.
Alla Bulashevska, Zsófia Nacsa, Franziska Lang, Markus Braun, Martin Machyna, Mustafa Diken, Liam Childs, Renate König   +7 more
doaj   +1 more source