Results 61 to 70 of about 803,197 (352)

Characterising two-pathogen competition in spatially structured environments [PDF]

, 2014
Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space structure of the ...
Colizza, Vittoria, Meloni, Sandro, Moreno, Yamir, Poletto, Chiara, Van Metre, Ashleigh, Vespignani, Alessandro   +5 more
core   +4 more sources

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit

Nature Communications, 2018
SAMHD1 is a critical restriction factor for HIV-1 and its antiviral activity is regulated by T592 phosphorylation. Here, Schott et al. show that the phosphatase PP2A-B55α dephosphorylates SAMHD1 during mitotic exit, rendering it antivirally active in G1 ...
Kerstin Schott, Nina V. Fuchs, Rita Derua, Bijan Mahboubi, Esther Schnellbächer, Janna Seifried, Christiane Tondera, Heike Schmitz, Caitlin Shepard, Alberto Brandariz-Nuñez, Felipe Diaz-Griffero, Andreas Reuter, Baek Kim, Veerle Janssens, Renate König   +14 more
doaj   +1 more source

Understanding Host–Pathogen Interactions in Brassica napus in the Omics Era

Plants, 2020
Brassica napus (canola/oilseed rape/rapeseed) is an economically important crop, mostly found in temperate and sub-tropical regions, that is cultivated widely for its edible oil.
T. Neik, J. Amas, M. Barbetti, D. Edwards, J. Batley   +4 more
semanticscholar   +1 more source

Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils

Frontiers in Immunology, 2020
Polymorphonuclear neutrophils (PMN) are critical for first line innate immune defence against Staphylococcus aureus. Mature circulating PMN maintain a short half-life ending in constitutive apoptotic cell death.
Michelle E. Mulcahy, Eóin C. O’Brien, Kate M. O’Keeffe, Emilio G. Vozza, Neal Leddy, Rachel M. McLoughlin   +5 more
doaj   +1 more source

Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]

, 2014
Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T., Louis C., Matsumoto A., Matsumoto A., Newhall W.J., Scidmore M.A., Ward M.E.   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Role of PQBP1 in Pathogen Recognition—Impact on Innate Immunity

Viruses
The intrinsically disordered polyglutamine-binding protein 1 (PQBP1) has been linked to various cellular processes including transcription, alternative splicing, translation and innate immunity.
Lukas Wiench, Domenico Rizzo, Zora Sinay, Zsófia Nacsa, Nina V. Fuchs, Renate König   +5 more
doaj   +1 more source

Molecular surveillance of Cryptosporidium spp. for microbial source tracking of fecal contamination in Laguna Lake, Philippines

Journal of Water and Health, 2021
Water quality deterioration in source waters poses increased health, environmental, and economic risks. Here, we genotyped Cryptosporidium spp. obtained from water samples of Laguna Lake, Philippines, and its tributaries for the purpose of source ...
Laurice Beatrice Raphaelle O. dela Peña, Mark Raymond A. Vejano, Windell L. Rivera   +2 more
doaj   +1 more source

A novel Arabidopsis pathosystem reveals cooperation of multiple hormonal response-pathways in host resistance against the global crop destroyer Macrophomina phaseolina. [PDF]

, 2019
Dubbed as a "global destroyer of crops", the soil-borne fungus Macrophomina phaseolina (Mp) infects more than 500 plant species including many economically important cash crops. Host defenses against infection by this pathogen are poorly understood.
Alsalek, Natalie, Eulgem, Thomas, Lai, Yan, Roberts, Philip, Schroeder, Mercedes M, Shirai, Miwa, Tsuchiya, Tokuji   +6 more
core   +1 more source

Adaptive Dynamics of Pathogen-Host Interactions [PDF]

, 2002
This paper explains why the traditional approach of predicting evolutionary outcomes by maximizing the basic reproduction ratio of a disease is not always appropriate.
Dieckmann, U.
core   +2 more sources