Natural Cyclooxygenase-2 Inhibitors Synergize With Butyrate to Augment Chicken Host Defense Peptide Gene Expression. [PDF]
Yang Q +4 more
europepmc +1 more source
Interaction and Cellular Localization of the Human Host Defense
LL-37 is a human cationic host defense peptide that is an essential component of innate immunity. In addition to its modest antimicrobial activity, LL-37 affects the gene expression and behavior of effector cells involved in the innate immune response ...
Lung Epithelial Cells +7 more
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SSTP1, a Host Defense Peptide, Exploits the Immunomodulatory IL6 Pathway to Induce Apoptosis in Cancer Cells. [PDF]
Gopalakrishnan S +12 more
europepmc +1 more source
Comparative Meta‐Analysis of Antimicrobial Peptides in Aquatic and Terrestrial Livestock Species
A global meta‐analysis of 58 studies (926 effect sizes and 29 species across five taxa) revealed that dietary antimicrobial peptides generally improve growth performance, blood metabolites, and immune responses. The greatest benefits were observed in omnivorous livestock, such as pigs and chickens. Dose‐duration effects were evident. An optimal outcome
Lily Liu +4 more
wiley +1 more source
Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors. [PDF]
Whitmore MA +4 more
europepmc +1 more source
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu +11 more
wiley +1 more source
Quorum Sensing Pseudomonas Quinolone Signal Forms Chiral Supramolecular Assemblies With the Host Defense Peptide LL-37. [PDF]
Zsila F +4 more
europepmc +1 more source
Evaluating Host Defense Peptides
The global antibiotic resistance crisis raises concerns about antibiotic use, and alternative strategies are urgently needed. In this context, host defense peptides (HDPs) have rapidly gained interest. However, one of the main obstacles is their production strategy.
Saubi, Cristina|| +6 more
openaire +1 more source
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source
Murepavadin, a Small Molecule Host Defense Peptide Mimetic, Activates Mast Cells via MRGPRX2 and MrgprB2. [PDF]
Amponnawarat A +2 more
europepmc +1 more source

