Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez +7 more
wiley +1 more source
Multifunctional host defense peptides [PDF]
The FEBS Journal, 2009 Pierre Nicolas, Yvonne Rosenstein
openaire +1 more source
Translational Macrophage Mechano‐Immunotherapy for Next‐Generation Implantable Biomaterials
Advanced NanoBiomed Research, EarlyView.This review explores how macrophage mechanosensing drives inflammation, fibrosis and foreign body responses to implanted biomaterials. It examines emerging pharmacological strategies to modulate mechanotransduction, alongside biomaterial platforms for localised drug delivery, clinical translation, regulatory considerations and standardised testing ...
Xueying Xu, Ian L. Chin, Richard P. Tan
wiley +1 more source
Large-Scale Identification of Multiple Classes of Host Defense Peptide-Inducing Compounds for Antimicrobial Therapy. [PDF]
Int J Mol Sci, 2022 Lyu W, Mi D, Vinson PN, Xiao Y, Zhang G.
europepmc +1 more source
Advanced NanoBiomed Research, EarlyView.Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang +12 more
wiley +1 more source
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
High-Throughput Identification of Epigenetic Compounds to Enhance Chicken Host Defense Peptide Gene Expression. [PDF]
Antibiotics (Basel), 2022 Deng Z, Lyu W, Zhang G.
europepmc +1 more source
Report of Secretary of Defense to the Congress on the ... Defense budget and ... Defense program.
Includes transition budgets, authorization request and defense programs.Title varies slightly.Report year ends June 30.Mode of access ...
United States. Dept. of Defense.
core
Synergistic Induction of Chicken Antimicrobial Host Defense Peptide Gene Expression by Butyrate and Sugars. [PDF]
Front Microbiol, 2021 Yang Q +5 more
europepmc +1 more source
Biodistribution of the cationic host defense peptide LL-37 using SPECT/CT
Human cathelicidin LL-37, a cationic host defense peptide (CHDP), has several important physiological roles, including antimicrobial activity, immune modulation, and wound healing, and is a being investigated as a therapeutic candidate for several ...
Blackadar, Colin +6 more
core +1 more source