Results 41 to 50 of about 2,543,243 (266)
Microbiology Spectrum, 2022 Klebsiella pneumoniae produces a thick capsule layer composed of extracellular polysaccharides protecting the bacterial cells from clearance by innate host immunity during infection.
Renee M. Fleeman, Bryan W. Davies
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Veterinary Research, 2018 Innate defense mechanisms are aimed at quickly containing and removing infectious microorganisms and involve local stromal and immune cell activation, neutrophil recruitment and activation and the induction of host defense peptides (defensins and ...
Albert van Dijk +3 more
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Humoral immunity in insects: Antimicrobial peptides and other host defense peptides [PDF]
The discovery of antimicrobial peptides in insects in the 1980s helped lay the foundation for the field of humoral innate immunity in animals. These molecules were first identified owing to their microbe-killing activity, promising novel strategies for ...
MA Hanson (11817563) +1 more
core +4 more sources
Differential expression of immune defences is associated with specific host-parasite interactions in insects [PDF]
, 2009 Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broadspectrum ...
Carolyn Riddell +16 more
core +2 more sources
Computational and Structural Biotechnology Journal, 2022 The burgeoning menace of antimicrobial resistance across the globe has necessitated investigations into other chemotherapeutic strategies to combat infections.
Sukriyo Chakraborty +2 more
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Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity.
PLoS ONE, 2014 Cationic, amphipathic host defense peptides represent a promising group of agents to be developed for anticancer applications. Poly-N-substituted glycines, or peptoids, are a class of biostable, peptidomimetic scaffold that can display a great diversity ...
Wei Huang +6 more
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The Roles of Antimicrobial Peptides in Innate Host Defense [PDF]
Current Pharmaceutical Design, 2009 Antimicrobial peptides (AMPs) are multi-functional peptides whose fundamental biological role in vivo has been proposed to be the elimination of pathogenic microorganisms, including Gram-positive and -negative bacteria, fungi, and viruses. Genes encoding these peptides are expressed in a variety of cells in the host, including circulating phagocytic ...
Gill, Diamond +3 more
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Bioprospecting the American alligator (Alligator mississippiensis) host defense peptidome. [PDF]
PLoS ONE, 2015 Cationic antimicrobial peptides and their therapeutic potential have garnered growing interest because of the proliferation of bacterial resistance.
Barney M Bishop +9 more
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Regulation of Host Defense Peptide Synthesis by Polyphenols
Antibiotics, 2023 The rise of antimicrobial resistance has created an urgent need for antibiotic-alternative strategies for disease control and prevention. Host defense peptides (HDPs), which have both antimicrobial and immunomodulatory properties, are an important component of the innate immune system.
Isabel Tobin, Guolong Zhang
openaire +3 more sources
Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018
Pharmaceutics, 2023 The multifunctional properties of host defense peptides (HDPs) make them promising drug candidates to tackle bacterial infections and tissue inflammation.
Hashem Etayash +2 more
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