Results 31 to 40 of about 76,743 (235)
Reassessing the Host Defense Peptide Landscape [PDF]
Frontiers in Chemistry, 2019 Current research has demonstrated that small cationic amphipathic peptides have strong potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and anti-inflammatories. Although traditionally termed antimicrobial peptides (AMPs) these additional roles have prompted a shift in terminology to use the broader term host ...
Evan F. Haney +2 more
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Bacterial Evasion of Host Antimicrobial Peptide Defenses [PDF]
Microbiology Spectrum, 2016 ABSTRACT Antimicrobial peptides (AMPs), also known as host defense peptides, are small naturally occurring microbicidal molecules produced by the host innate immune response that function as a first line of defense to kill pathogenic microorganisms by inducing deleterious cell membrane damage.
Cole, Jason N., Nizet, Victor
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Frontiers in Microbiology, 2013 Lipopolysaccharides (LPS) are the major molecular component of the outer membrane of Gram-negative bacteria. This molecule is recognized as a sign of bacterial infection, responsible for the development of local inflammatory response and, in extreme ...
Carlos eLopez-Abarrategui +4 more
doaj +1 more source
Immunomodulatory Activities of Small Host Defense Peptides [PDF]
Antimicrobial Agents and Chemotherapy, 2005 ABSTRACT Recent studies have demonstrated that in addition to their antimicrobial activity, cationic host defense peptides, like the human cathelicidin LL-37, perform many activities relating to innate immunity, including the induction or modulation of chemokine and cytokine production, alteration of gene expression in host cells,
Bowdish, Dawn M E +3 more
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Veterinary Research, 2018 Innate defense mechanisms are aimed at quickly containing and removing infectious microorganisms and involve local stromal and immune cell activation, neutrophil recruitment and activation and the induction of host defense peptides (defensins and ...
Albert van Dijk +3 more
doaj +1 more source
PhytoAFP: In Silico Approaches for Designing Plant-Derived Antifungal Peptides
Antibiotics, 2021 Emerging infectious diseases (EID) are serious problems caused by fungi in humans and plant species. They are a severe threat to food security worldwide.
Atul Tyagi +6 more
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Host Defense Peptides in Wound Healing
Molecular Medicine, 2008 Host defense peptides are effector molecules of the innate immune system. They show broad antimicrobial action against gram-positive and -negative bacteria, and they likely play a key role in activating and mediating the innate as well as adaptive immune response in infection and inflammation. These features make them of high interest for wound healing
Lars, Steinstraesser +9 more
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The Roles of Antimicrobial Peptides in Innate Host Defense [PDF]
Current Pharmaceutical Design, 2009 Antimicrobial peptides (AMPs) are multi-functional peptides whose fundamental biological role in vivo has been proposed to be the elimination of pathogenic microorganisms, including Gram-positive and -negative bacteria, fungi, and viruses. Genes encoding these peptides are expressed in a variety of cells in the host, including circulating phagocytic ...
Gill, Diamond +3 more
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A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes. [PDF]
PLoS ONE, 2016 Conventional antibiotics and other chemical-based drugs are currently one of the most common methods used to control disease-related mortality in animal agriculture.
Scott A Salger +3 more
doaj +1 more source
Marine Invertebrate Antimicrobial Peptides and Their Potential as Novel Peptide Antibiotics
Marine Drugs, 2023 Marine invertebrates constantly interact with a wide range of microorganisms in their aquatic environment and possess an effective defense system that has enabled their existence for millions of years.
Svetlana V. Guryanova +3 more
doaj +1 more source