Results 31 to 40 of about 2,543,243 (266)
Oncolytic Activities of Host Defense Peptides [PDF]
International Journal of Molecular Sciences, 2011 Cancer continues to be a leading source of morbidity and mortality worldwide in spite of progress in oncolytic therapies. In addition, the incidence of cancers affecting the breast, kidney, prostate and skin among others continue to rise. Chemotherapeutic drugs are widely used in cancer treatment but have the serious drawback of nonspecific toxicity ...
Benna, Sammy al- +3 more
openaire +3 more sources
Molecules, 2023 Antimicrobial peptides (AMPs) are essential components of innate immunity across all species. AMPs have become the focus of attention in recent years, as scientists are addressing antibiotic resistance, a public health crisis that has reached epidemic ...
Caroline Donaghy +4 more
doaj +1 more source
Antimicrobial peptides in echinoderm host defense [PDF]
Developmental & Comparative Immunology, 2015 Antimicrobial peptides (AMPs) are important effector molecules in innate immunity. Here we briefly summarize characteristic traits of AMPs and their mechanisms of antimicrobial activity. Echinoderms live in a microbe-rich marine environment and are known to express a wide range of AMPs. We address two novel AMP families from coelomocytes of sea urchins:
Li, Chun +3 more
openaire +3 more sources
Reassessing the Host Defense Peptide Landscape [PDF]
Frontiers in Chemistry, 2019 Current research has demonstrated that small cationic amphipathic peptides have strong potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and anti-inflammatories. Although traditionally termed antimicrobial peptides (AMPs) these additional roles have prompted a shift in terminology to use the broader term host ...
Evan F. Haney +2 more
openaire +3 more sources
Bacterial Evasion of Host Antimicrobial Peptide Defenses [PDF]
Microbiology Spectrum, 2016 ABSTRACT Antimicrobial peptides (AMPs), also known as host defense peptides, are small naturally occurring microbicidal molecules produced by the host innate immune response that function as a first line of defense to kill pathogenic microorganisms by inducing deleterious cell membrane damage.
Cole, Jason N., Nizet, Victor
openaire +5 more sources
A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes. [PDF]
PLoS ONE, 2016 Conventional antibiotics and other chemical-based drugs are currently one of the most common methods used to control disease-related mortality in animal agriculture.
Scott A Salger +3 more
doaj +1 more source
Antiviral potential of cathelicidins [PDF]
, 2014 The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow.
Davidson, Donald J +8 more
core +1 more source
Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]
, 2012 Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C. +3 more
core +1 more source
Frontiers in Microbiology, 2013 Lipopolysaccharides (LPS) are the major molecular component of the outer membrane of Gram-negative bacteria. This molecule is recognized as a sign of bacterial infection, responsible for the development of local inflammatory response and, in extreme ...
Carlos eLopez-Abarrategui +4 more
doaj +1 more source
The Host Defense Proteome of Human and Bovine Milk [PDF]
, 2011 Milk is the single source of nutrients for the newborn mammal. The composition of milk of different mammals has been adapted during evolution of the species to fulfill the needs of the offspring.
Hooijdonk, A.C.M., van +20 more
core +2 more sources