Results 21 to 30 of about 2,543,243 (266)

Host Defense Peptides from Asian Frogs as Potential Clinical Therapies

open access: yesAntibiotics, 2015
Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological ...
Vineeth T.V. Kumar   +3 more
doaj   +2 more sources

Epithelial antimicrobial peptides in host defense against infection [PDF]

open access: yesRespiratory Research, 2000
One component of host defense at mucosal surfaces seems to be epithelium-derived antimicrobial peptides. Antimicrobial peptides are classified on the basis of their structure and amino acid motifs.
Bals Robert
doaj   +2 more sources

Evaluating Host Defense Peptides: A Comparative Analysis of Synthetic Peptides and Recombinant Concatemers [PDF]

open access: yesBiomolecules
The global antibiotic resistance crisis raises concerns about antibiotic use, and alternative strategies are urgently needed. In this context, host defense peptides (HDPs) have rapidly gained interest.
Cristina Saubi   +6 more
doaj   +2 more sources

The therapeutic potential of host-defense antimicrobial peptides

open access: yesCurrent Drug Targets, 2002
Species across the evolutionary scale from insects to mammals deploy peptides to counter microbial invaders. Although, there are considerable differences in the primary and secondary structures of these peptides, they exert their antimicrobial activity ...
Sitaram, N., Nagaraj, R.
core   +4 more sources

Antibacterial Peptides

open access: yesAntibiotics, 2020
As natural host defense compounds produced by numerous prokaryotic and eukaryotic life forms, antimicrobial peptides (AMPs) are now emerging as solid candidate chemotherapeutic drugs to fight against the various types of pathogenic Gram-positive and Gram-
Jean-Marc Sabatier
doaj   +2 more sources

Helminthic host defense peptides: using the parasite to defend the host

open access: yesTrends in Parasitology, 2023
: Parasitic helminths are destined to share niches with a variety of microbiota that inevitably influence their interaction with the host. To modulate the microbiome for their benefit and defend against pathogenic isolates, helminths have developed host ...
Roncevic T.   +7 more
core   +7 more sources

The Antimicrobial and Host Defense Peptides of Drosophila melanogaster [PDF]

open access: yesAnnual Review of Microbiology
Drosophila fruit flies are a powerful model for studying innate immunity. In Drosophila , seven classical antimicrobial peptide (AMP) gene families were identified in the 1990s.
Lemaitre, Bruno   +3 more
core   +4 more sources

Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Anna Mueller   +2 more
exaly   +2 more sources

Avian Antimicrobial Host Defense Peptides: From Biology to Therapeutic Applications

open access: yesPharmaceuticals, 2014
Host defense peptides (HDPs) are an important first line of defense with antimicrobial and immunomoduatory properties. Because they act on the microbial membranes or host immune cells, HDPs pose a low risk of triggering microbial resistance and therefore,
Guolong Zhang, Lakshmi T. Sunkara
doaj   +3 more sources

Host Defense Peptides in the Oral Cavity

open access: yes, 2008
International audienceHost defense peptides (HDPs) are important in defense of tissues throughout the human mouth. Like resident microbial populations, HDPs are diverse, species-specific, and site-specific, and they have evolved in response to selection ...
Cosseau, Celine   +3 more
core   +3 more sources

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