Results 21 to 30 of about 76,743 (235)

Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Julia P Deisinger   +2 more
exaly   +2 more sources

Regulation of the intestinal barrier function by host defense peptides

open access: yesFrontiers in Veterinary Science, 2015
Intestinal barrier function is achieved primarily through regulating the synthesis of mucins and tight junction proteins, which are critical for maintaining optimal gut health and animal performance.
Kelsy eRobinson   +4 more
doaj   +3 more sources

Host defense peptides clavanins A and MO reduce in vitro osteoclastogenesis

open access: yesBrazilian Journal of Oral Sciences, 2021
Aim: Several systemic diseases, such as periodontitis and apical periodontitis, can cause extensive bone resorption. Host defense peptides may have the potential for the development of novel therapies for the bone resorption process. This study evaluated
Ingrid Aquino Amorim   +6 more
doaj   +1 more source

The Synergy between Zinc and Antimicrobial Peptides: An Insight into Unique Bioinorganic Interactions

open access: yesMolecules, 2023
Antimicrobial peptides (AMPs) are essential components of innate immunity across all species. AMPs have become the focus of attention in recent years, as scientists are addressing antibiotic resistance, a public health crisis that has reached epidemic ...
Caroline Donaghy   +4 more
doaj   +1 more source

Oncolytic Activities of Host Defense Peptides [PDF]

open access: yesInternational Journal of Molecular Sciences, 2011
Cancer continues to be a leading source of morbidity and mortality worldwide in spite of progress in oncolytic therapies. In addition, the incidence of cancers affecting the breast, kidney, prostate and skin among others continue to rise. Chemotherapeutic drugs are widely used in cancer treatment but have the serious drawback of nonspecific toxicity ...
Benna, Sammy al-   +3 more
openaire   +3 more sources

Antimicrobial peptides in echinoderm host defense [PDF]

open access: yesDevelopmental & Comparative Immunology, 2015
Antimicrobial peptides (AMPs) are important effector molecules in innate immunity. Here we briefly summarize characteristic traits of AMPs and their mechanisms of antimicrobial activity. Echinoderms live in a microbe-rich marine environment and are known to express a wide range of AMPs. We address two novel AMP families from coelomocytes of sea urchins:
Li, Chun   +3 more
openaire   +3 more sources

Polyproline Peptide Aggregation with Klebsiella pneumoniae Extracellular Polysaccharides Exposes Biofilm Associated Bacteria

open access: yesMicrobiology Spectrum, 2022
Klebsiella pneumoniae produces a thick capsule layer composed of extracellular polysaccharides protecting the bacterial cells from clearance by innate host immunity during infection.
Renee M. Fleeman, Bryan W. Davies
doaj   +1 more source

Proteolysis of human thrombin generates novel host defense peptides. [PDF]

open access: yesPLoS Pathogens, 2010
The coagulation system is characterized by the sequential and highly localized activation of a series of serine proteases, culminating in the conversion of fibrinogen into fibrin, and formation of a fibrin clot.
Praveen Papareddy   +7 more
doaj   +1 more source

Evolving and assembling to pierce through: Evolutionary and structural aspects of antimicrobial peptides

open access: yesComputational and Structural Biotechnology Journal, 2022
The burgeoning menace of antimicrobial resistance across the globe has necessitated investigations into other chemotherapeutic strategies to combat infections.
Sukriyo Chakraborty   +2 more
doaj   +1 more source

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