Results 11 to 20 of about 145,208 (274)
Functions of Cationic Host Defense Peptides in Immunity [PDF]
Pharmaceuticals, 2016 Cationic host defense peptides are a widely distributed family of immunomodulatory molecules with antimicrobial properties. The biological functions of these peptides include the ability to influence innate and adaptive immunity for efficient resolution ...
Mahadevappa Hemshekhar +2 more
doaj +5 more sources
Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action [PDF]
International Journal of Molecular Sciences, 2021 The rapid rise of multidrug-resistant (MDR) bacteria has once again caused bacterial infections to become a global health concern. Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), offer a viable solution to these pathogens due to their diverse mechanisms of actions, which include direct killing as well as immunomodulatory ...
Julia P Deisinger +2 more
exaly +5 more sources
Antiviral Activities of Human Host Defense Peptides [PDF]
Current Medicinal Chemistry, 2020 Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout nature. As they participate in a number of different aspects of innate immunity in mammals, they have been termed Host Defense Peptides (HDPs). Due to their common structural features, including an amphipathic structure and cationic charge, they have been widely ...
David C Brice, Gill Diamond
exaly +4 more sources
Host defense peptides in malaria infection: their contributions, significance and constraints [PDF]
Malaria JournalPlasmodium-induced malaria infection remains a leading global health threat. Host defense peptides (HDPs), key components of innate immunity, target multiple stages of Plasmodium development through direct antimicrobial activity and immunomodulation ...
Dia Aldeen Alfaki +1 more
doaj +2 more sources
Evaluating Host Defense Peptides: A Comparative Analysis of Synthetic Peptides and Recombinant Concatemers [PDF]
BiomoleculesThe global antibiotic resistance crisis raises concerns about antibiotic use, and alternative strategies are urgently needed. In this context, host defense peptides (HDPs) have rapidly gained interest.
Cristina Saubi +6 more
doaj +2 more sources
Crosstalk Between Intestinal Microbiota and Host Defense Peptides in Fish [PDF]
BiologyThe intricate crosstalk between intestinal microbiota and host defense peptides (HDPs) in aquaculture has emerged as a cornerstone for advancing sustainable disease management and reducing reliance on antibiotics. This review synthesizes current insights
Xiao-Zheng Yu, Yang Yu, Zi-Yan Liu
doaj +2 more sources
Agronomy, 2022 Host-defense peptides (HDP) are emerging as promising phytosanitaries due to their potency, low plant, animal and environmental toxicity, and above all, low induction of antimicrobial resistance.
Fernando Lobo, Alicia Boto
doaj +3 more sources
Strategies in Translating the Therapeutic Potentials of Host Defense Peptides [PDF]
Frontiers in Immunology, 2020 The golden era of antibiotics, heralded by the discovery of penicillin, has long been challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides (HDPs), previously known as antimicrobial peptides, are emerging as a group of ...
Darren Shu Jeng Ting +7 more
doaj +2 more sources
Cathelicidin Host Defense Peptides and Inflammatory Signaling: Striking a Balance [PDF]
Frontiers in Microbiology, 2020 Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates. While their antibacterial activity toward bacterial cells was the original focus for research, their ability to modulate immune and inflammatory processes has ...
Morgan A. Alford +5 more
doaj +2 more sources
Epithelial antimicrobial peptides in host defense against infection [PDF]
Respiratory Research, 2000 One component of host defense at mucosal surfaces seems to be epithelium-derived antimicrobial peptides. Antimicrobial peptides are classified on the basis of their structure and amino acid motifs.
Bals Robert
doaj +3 more sources