Results 11 to 20 of about 76,743 (235)
Functions of Cationic Host Defense Peptides in Immunity [PDF]
Pharmaceuticals, 2016 Cationic host defense peptides are a widely distributed family of immunomodulatory molecules with antimicrobial properties. The biological functions of these peptides include the ability to influence innate and adaptive immunity for efficient resolution ...
Mahadevappa Hemshekhar +2 more
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Antiviral Activities of Human Host Defense Peptides [PDF]
Current Medicinal Chemistry, 2020 Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout nature. As they participate in a number of different aspects of innate immunity in mammals, they have been termed Host Defense Peptides (HDPs). Due to their common structural features, including an amphipathic structure and cationic charge, they have been widely ...
David C Brice, Gill Diamond
exaly +4 more sources
Host Defense Peptides as Templates for Antifungal Drug Development [PDF]
Journal of Fungi, 2020 Current treatment for invasive fungal diseases is limited to three classes of antifungal drugs: azoles, polyenes, and echinocandins. The most recently introduced antifungal class, the echinocandins, was first approved nearly 30 years ago.
Virginia Basso +3 more
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Evaluating Host Defense Peptides: A Comparative Analysis of Synthetic Peptides and Recombinant Concatemers [PDF]
BiomoleculesThe global antibiotic resistance crisis raises concerns about antibiotic use, and alternative strategies are urgently needed. In this context, host defense peptides (HDPs) have rapidly gained interest.
Cristina Saubi +6 more
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Crosstalk Between Intestinal Microbiota and Host Defense Peptides in Fish [PDF]
BiologyThe intricate crosstalk between intestinal microbiota and host defense peptides (HDPs) in aquaculture has emerged as a cornerstone for advancing sustainable disease management and reducing reliance on antibiotics. This review synthesizes current insights
Xiao-Zheng Yu, Yang Yu, Zi-Yan Liu
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Agronomy, 2022 Host-defense peptides (HDP) are emerging as promising phytosanitaries due to their potency, low plant, animal and environmental toxicity, and above all, low induction of antimicrobial resistance.
Fernando Lobo, Alicia Boto
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Strategies in Translating the Therapeutic Potentials of Host Defense Peptides [PDF]
Frontiers in Immunology, 2020 The golden era of antibiotics, heralded by the discovery of penicillin, has long been challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides (HDPs), previously known as antimicrobial peptides, are emerging as a group of ...
Darren Shu Jeng Ting +7 more
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Cathelicidin Host Defense Peptides and Inflammatory Signaling: Striking a Balance [PDF]
Frontiers in Microbiology, 2020 Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates. While their antibacterial activity toward bacterial cells was the original focus for research, their ability to modulate immune and inflammatory processes has ...
Morgan A. Alford +5 more
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Host Defense Peptides from Asian Frogs as Potential Clinical Therapies
Antibiotics, 2015 Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological ...
Vineeth T.V. Kumar +3 more
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Avian Antimicrobial Host Defense Peptides: From Biology to Therapeutic Applications
Pharmaceuticals, 2014 Host defense peptides (HDPs) are an important first line of defense with antimicrobial and immunomoduatory properties. Because they act on the microbial membranes or host immune cells, HDPs pose a low risk of triggering microbial resistance and therefore,
Guolong Zhang, Lakshmi T. Sunkara
doaj +3 more sources