Results 91 to 100 of about 871,394 (166)

Material-Sparing Feasibility Screening for Hot Melt Extrusion

Pharmaceutics
Hot melt extrusion (HME) offers a high-throughput process to manufacture amorphous solid dispersions. A variety of experimental and model-based approaches exist to predict API solubility in polymer melts, but these methods are typically aimed at ...
Amanda Pluntze, Scott Beecher, Maria Anderson, Dillon Wright, Deanna Mudie   +4 more
doaj   +1 more source

Stability of Dexamethasone during Hot-Melt Extrusion of Filaments based on Eudragit® RS, Ethyl Cellulose and Polyethylene Oxide

International Journal of Pharmaceutics: X
Hot-melt extrusion (HME) potentially coupled with 3D printing is a promising technique for the manufacturing of dosage forms such as drug-eluting implants which might even be individually adapted to patient-specific anatomy.
Vanessa Domsta, Tessa Boralewski, Martin Ulbricht, Philipp Schick, Julius Krause, Anne Seidlitz   +5 more
doaj   +1 more source

Eco-Friendly Enhancement of Ferulic Acid-Rich Extracts from Cnidium officinale and Angelica gigas via Hot-Melt Extrusion for Skin Brightening and Regeneration

Cosmetics
Cnidium officinale (CO) and Angelica gigas (AG) are traditional herbal medicines known for their bioactive compound ferulic acid (FA), which exerts skin-whitening, anti-inflammatory, antioxidant, and UV-protective effects.
Yoo-Na Jeon, Han-Sol You, So-Hee Jang, Jong-Suep Baek   +3 more
doaj   +1 more source

Impact of Hot-Melt Extrusion on Glibenclamide’s Physical and Chemical States and Dissolution Behavior: Case Studies with Three Polymer Blend Matrices

Pharmaceutics
This research work dives into the complexity of hot-melt extrusion (HME) and its influence on drug stability, focusing on solid dispersions containing 30% of glibenclamide and three 50:50 polymer blends.
Nina Zupan, Ines Yous, Florence Danede, Jeremy Verin, Mostafa Kouach, Catherine Foulon, Emeline Dudognon, Susanne Florin Muschert   +7 more
doaj   +1 more source

Model-based formulation of amorphous solid dispersions made by hot-melt extrusion [PDF]

, 2019
Regarding hot-melt extrusion in early pharmaceutical formulation and process development, techniques and procedures are needed to simplify the application of hot-melt extrusion (HME) and to decrease the effort in terms of material and time.
Bochmann, Esther Sophia
core   +1 more source

Fabricação por extrusão de dispositivos poliméricos para liberação de antibiótico visando aplicações médicas [PDF]

, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência e Engenharia dos Materiais, Florianópolis, 2011O intento inicial deste trabalho fez-se na escolha de uma técnica de fabricação que ...
Zepon, Karine Modolon
core  

BEYOND THE HORIZON: RECENT ADVANCES IN HOT MELT EXTRUSION TECHNIQUES AND TECHNOLOGIES

This review article aims to explore the dynamic landscape of Hot Melt Extrusion (HME) technology, focusing on the spectrum of materials and machinery shaping innovation in the field.
ALKANAD, MAGED, PATIL, DARSHAN, ABDO MOHSEN, MAGED MOHAMMED, PATIL, AMIT B.   +3 more
core   +1 more source

Precision Drug Delivery of LY-11h for Acute Myeloid Leukemia Treatment Using Machine Learning-Assisted Hot Melt Extrusion and 3D-Printed Technologies. [PDF]

Pharmaceutics
Huang L, Li D, Yang T, Yang W, Zhu M, Zhao X, Zhang J.   +6 more
europepmc   +1 more source

Exploring the pivotal role of hot melt extrusion technology in developing PLGA based novel drug delivery platforms for better therapeutic outcomes. [PDF]

Saudi Pharm J
Almutairi M, Almuhwes RH, Alshammari JA, Alsleem HF, Algharbi GN, Alsowaida YS, Almuntashiri S, Alobaida A.   +7 more
europepmc   +1 more source

HME-FDM 3D-Printed Implantable Drug Delivery Systems-From Design to Characterization. [PDF]

Pharmaceutics
Vámosi B, Bácskay I, Fehér P, Ujhelyi Z, Arany P.   +4 more
europepmc   +1 more source