Results 91 to 100 of about 924,399 (169)

BEYOND THE HORIZON: RECENT ADVANCES IN HOT MELT EXTRUSION TECHNIQUES AND TECHNOLOGIES

open access: yes
This review article aims to explore the dynamic landscape of Hot Melt Extrusion (HME) technology, focusing on the spectrum of materials and machinery shaping innovation in the field.
ALKANAD, MAGED   +3 more
core   +1 more source

Revolutionizing Personalized Medicine: 3D-Printed Drug Dosage Forms via Hot Melt Extrusion [PDF]

open access: yes
Recent advancements in pharmaceutical manufacturing are paving the way for highly personalized and on-demand therapies. This article discusses a novel approach that integrates Hot Melt Extrusion (HME) with 3D printing to produce drug dosage forms with ...
Arora , Pooja, Kumar, Amit
core   +1 more source

Dispersion and dissolution kinetics of API particles in pharmaceutical hot melt extrusion [PDF]

open access: yes, 2014
Pharmaceutical Hot Melt Extrusion (HME) is essentially a special case of polymer compounding. The elementary steps involved in traditional plastics melt processing are handling of particulates, melting, dispersive and distributive mixing ...
Zhan, Wang
core   +1 more source

Stability of Dexamethasone during Hot-Melt Extrusion of Filaments based on Eudragit® RS, Ethyl Cellulose and Polyethylene Oxide

open access: yesInternational Journal of Pharmaceutics: X
Hot-melt extrusion (HME) potentially coupled with 3D printing is a promising technique for the manufacturing of dosage forms such as drug-eluting implants which might even be individually adapted to patient-specific anatomy.
Vanessa Domsta   +5 more
doaj   +1 more source

Hot-melt extrusion technology and pharmaceutical application

open access: yes, 2012
The use of hot-melt extrusion (HME) within the pharmaceutical industry is steadily increasing, due to its proven ability to efficiently manufacture novel products.
Wilson, M.   +3 more
core   +1 more source

Eco-Friendly Enhancement of Ferulic Acid-Rich Extracts from Cnidium officinale and Angelica gigas via Hot-Melt Extrusion for Skin Brightening and Regeneration

open access: yesCosmetics
Cnidium officinale (CO) and Angelica gigas (AG) are traditional herbal medicines known for their bioactive compound ferulic acid (FA), which exerts skin-whitening, anti-inflammatory, antioxidant, and UV-protective effects.
Yoo-Na Jeon   +3 more
doaj   +1 more source

Review paper: Processing aspects of hot melt extrusion in pharmaceutical applications

open access: yes, 2009
Applying extrusion technology to drug manufacturing received increasing attention in the last two decades. Extrusion technology has the potential of replacing current Pharmaceuticals manufacturing methods due to the advantages such as the elimination of ...
Wang, Peng   +4 more
core  

Hot Melt Extrusion as Solvent-Free Technique for a Continuous Manufacturing of Drug-Loaded Mesoporous Silica

open access: yes, 2018
The aim of this study is to explore hot melt extrusion (HME) as a solvent-free drug loading technique for preparation of stable amorphous solid dispersions using mesoporous silica (PSi).
Genina, Natalja   +5 more
core   +1 more source

Impact of Hot-Melt Extrusion on Glibenclamide’s Physical and Chemical States and Dissolution Behavior: Case Studies with Three Polymer Blend Matrices

open access: yesPharmaceutics
This research work dives into the complexity of hot-melt extrusion (HME) and its influence on drug stability, focusing on solid dispersions containing 30% of glibenclamide and three 50:50 polymer blends.
Nina Zupan   +7 more
doaj   +1 more source

A review of hot-melt extrusion: process technology to pharmaceutical products

open access: yes, 2012
Over the last three decades industrial adaptability has allowed hot-melt extrusion (HME) to gain wide acceptance and has already established its place in the broad spectrum of manufacturing operations and pharmaceutical research developments.
Joshua S Boateng (16228832)   +3 more
core  

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