Heat Shock Protein 27(HSP27) in Kidney Disease: Potentials for Diagnosis and Therapy [PDF]
Journal of Advanced Pharmacy Research, 2017 The small HSP27 is an actin-specific molecular chaperone involved in cytoskeleton architecture, cell migration, metabolism, survival, growth/differentiation, mRNA stabilization, and tumor progression.
Shahenda Mahgoub
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Pathogens, 2023 Heat shock protein 27 (HSP27) is a multifunctional protein and belongs to the small HSP family. It has been shown that HSP27 is involved in viral replication as a cellular chaperone, but the function of HSP27 during porcine reproductive and respiratory ...
Chunhui Song +4 more
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Expression and clinical significance of HSP27 and its phosphorylation in lower extremity arteriosclerosis obliterans [PDF]
PeerJ, 2020 Objectives This study set out to analyze the difference of heat shock protein 27 (HSP27) and its phosphorylation in patients with lower extremity arteriosclerosis obliterans (LEASO) at different stages.
Junqing Bai +7 more
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Profile of Serum Heat Shock Protein-27 Level in Patients with Salivary Gland Tumor [PDF]
Journal of Dentistry, 2022 Statement of the Problem: Heat shock protein 27 (HSP27) plays important roles in many cellular processes and has been implicated in different types of diseases such as cancers.Purpose: This study aimed to evaluate the serum level of HSP27 in patients ...
Negar Moghadasi +6 more
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HSP27 induced glaucomatous damage in mice of young and advanced age
Frontiers in Cellular Neuroscience, 2023 IntroductionAge-related diseases such as glaucoma, a leading cause of blindness, are having an upward trend due to an aging society. In glaucoma, some patients display altered antibody profiles and increased antibody titers, for example against heat ...
Clivia Erb +4 more
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Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway
Biomolecules, 2021 Cancer stem cells (CSCs), a subpopulation of cancer cells responsible for tumor initiation and treatment failure, are more susceptible to ferroptosis-inducing agents than bulk cancer cells.
Chen-Chi Liu +8 more
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Cancer Cell International, 2023 Background Glioblastoma is one of the malignant tumors of the central nervous system with high lethality, high disability and low survival rate. Effective induction of its death is one of the existing challenges. In recent studies, heat shock protein 27 (
Kai Zhang +5 more
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Cell Death Discovery, 2021 Heat shock protein 27 (HSP27), a regulator of cell survival, can enhance the resistance of cancer cells to radiotherapy. As microRNA-541-3p (miR-541-3p) was recently predicted to be a putative upstream modulator of HSP27, the present study was designed ...
Zhenhua He +4 more
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Release of Phosphorylated HSP27 (HSPB1) from Platelets Is Accompanied with the Acceleration of Aggregation in Diabetic Patients. [PDF]
PLoS ONE, 2015 We investigated the relationship between HSP27 phosphorylation and collagen-stimulated activation of platelets in patients with diabetes mellitus (DM). Platelet-rich plasma was prepared from blood of type 2 DM patients.
Haruhiko Tokuda +17 more
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Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases. [PDF]
PLoS ONE, 2015 Pulmonary metastases are common in patients with primary colorectal cancer (CRC). Heat-shock protein 27 (Hsp27) is upregulated in activated fibroblasts during wound healing and systemically elevated in various diseases.
Thomas Schweiger +12 more
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