Results 31 to 40 of about 18,813 (211)

Serum heat shock protein 27 levels predict cardiac mortality in hemodialysis patients

BMC Nephrology, 2018
Background Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as well as to evaluate factors ...
Andrzej Jaroszyński, Anna Jaroszyńska, Tomasz Zaborowski, Anna Drelich-Zbroja, Tomasz Zapolski, Wojciech Dąbrowski   +5 more
doaj   +1 more source

Silencing Heat Shock Protein 27 Inhibits the Progression and Metastasis of Colorectal Cancer (CRC) by Maintaining the Stability of Stromal Interaction Molecule 1 (STIM1) Proteins

Cells, 2018
The incidence of colorectal cancer (CRC) has significantly increased in recent decades, and this disease has become an important health issue worldwide. Currently, there is no useful prognostic or diagnostic biomarker for CRC.
Chien-Yu Huang, Po-Li Wei, Wei-Yu Chen, Wei-Chiao Chang, Yu-Jia Chang   +4 more
doaj   +1 more source

Sulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Up-regulation of Hsp27

, 2010
It is conceivable that stimulating proteasome activity for rapid removal of misfolded and oxidized proteins is a promising strategy to prevent and alleviate aging-related diseases.
Gan, Nanqin, Brunet, Mathilde, Carmen Garrido, Garrido, Carmen, Mi, Lixin, Mi, LX, Georgetown Univ, Lombardi Comprehens Canc Ctr, Dept Oncol, 3800 Reservoir Rd,LL 129,Box 571465, Washington, DC 20057 USA, Chung, Fung-Lung, Nanqin Gan, Yu-Chieh Wu, Wu, Yu-Chieh, Fung-Lung Chung, Lixin Mi, Dai, Chengkai, Mathilde Brunet, Chengkai Dai   +14 more
core   +1 more source

Quantitative Immunomorphological Analysis of Heat Shock Proteins in Thyroid Follicular Adenoma and Carcinoma Tissues Reveals Their Potential for Differential Diagnosis and Points to a Role in Carcinogenesis

Applied Sciences, 2019
Hsp27, Hsp60, Hsp70, and Hsp90 are chaperones that play a crucial role in cellular homeostasis and differentiation, but they may be implicated in carcinogenesis. Follicular neoplasms of the thyroid include follicular adenoma and follicular carcinoma. The
Alessandro Pitruzzella, Letizia Paladino, Alessandra Maria Vitale, Stefania Martorana, Calogero Cipolla, Giuseppa Graceffa, Daniela Cabibi, Sabrina David, Alberto Fucarino, Fabio Bucchieri, Francesco Cappello, Everly Conway de Macario, Alberto JL Macario, Francesca Rappa   +13 more
doaj   +1 more source

HSP27 release and cell-signaling.

, 2013
In response to estrogenic stimulation or to atherogenic stress induced by elevated serum cholesterol levels, HSP27 is released into the extracellular space via an exosomal pathway.
Charles M. Cuerrier (284447), XiaoLing Zhao (284454), Edward R. O'Brien (88831), Dominique Tremblay (284450), Yong-Xiang Chen (284449), Katey Rayner (284452), Christopher R. J. Kennedy (284455), Jacqueline de BelleRoche (284456), Andrew E. Pelling (284457), Melissa McNulty (284453)   +9 more
core   +1 more source

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

Advanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang, Zhudong Liu, Yuqiao Yin, Jing Su, Dunyang Yu, Longsheng Xing, Zhen Zou, Le Kang, Jianghua Sun   +8 more
wiley   +1 more source

Translocation of HSP27 and MKBP in Ischemic Heart.

Cell Structure and Function, 1999
HSP27 and MKBP translocate from the cytosolic to myofibril fraction in ischemic rat heart as demonstrated by immunoblotting. Immunohistochemistry analysis showed that ischemia enhances the Z line labeling of HSP27 and MKBP. Two dimensional gel electrophoresis showed that ischemia increases the hyperphosphorylated form of HSP27.
Yoshida, Ken-ichi, Aki, Toshihiko, Harada, Kazuki, M.A. Shama, Kazi, Kamoda, Yasuhisa, Suzuki, Atsushi, Ohno, Shigeo   +6 more
openaire   +3 more sources

Hsp27 sian stressi-indikaattorina [PDF]

, 2007
Lämpösokkiproteiinit (heat shock protein, hsp, stressiproteiini) ovat solunsisäisiä proteiineja, joita solu valmistaa sekä jatkuvasti että vasteena kohtaamalleen stressille.
Piironen, Heidi
core  

HSP27 and cell survival in neurones

International Journal of Hyperthermia, 2005
Although the majority of studies on the protective effect of individual hsps have concentrated on the major inducible heat shock protein Hsp70, a variety of evidence suggests that the small heat shock protein Hsp27 may have a more potent protective effect in the nervous system.
openaire   +2 more sources

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source