Results 61 to 70 of about 83,455 (287)
Advanced Science, EarlyView.Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang +5 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Host nectin-1 is required for efficient Chlamydia trachomatis serovar E development.
Frontiers in Cellular and Infection Microbiology, 2014 Interaction of Herpes Simplex Virus (HSV) glycoprotein D (gD) with the host cell surface during Chlamydia trachomatis/HSV co-infection stimulates chlamydiae to become persistent.
Jennifer Vanover Hall +9 more
doaj +1 more source
HSV-1 Triggers an Antiviral Transcriptional Response during Viral Replication That Is Completely Abrogated in PKR−/− Cells [PDF]
, 2023 Rosamaria Pennisi +1 more
openalex +1 more source
Advanced Intelligent Systems, EarlyView.This article proposes a lightweight YOLOv4‐based detection model using MobileNetV3 or CSPDarknet53_tiny, achieving 30+ FPS and higher mAP. It also presents a ShuffleNet‐based classification model with transfer learning and GAN‐augmented images, improving generalization and accuracy.
Qingyang Liu, Yanrong Hu, Hongjiu Liu
wiley +1 more source
American Journal of Community Psychology, EarlyView.Abstract Black women face a myriad of challenges that heighten their susceptibility to sexually transmitted infections (STIs), resulting in a disproportionate impact of STIs among this population. Yet, there is a lack of research that explores how women navigate these diagnoses with resilience.
Jaleah D. Rutledge +3 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud +3 more
wiley +1 more source
Amentoflavone Inhibits HSV-1 and ACV-Resistant Strain Infection by Suppressing Viral Early Infection
Viruses, 2019 Infection of Herpes simplex virus 1 (HSV-1) induces severe clinical disorders, such as herpes simplex encephalitis and keratitis. Acyclovir (ACV) is the current therapeutic drug against viral infection and ACV-resistant strains have gradually emerged ...
Feng Li +10 more
doaj +1 more source
Antibodies against HSV-1 and Curli Show the Highest Correlation in Parkinson’s Disease Patients in Comparison to Healthy Controls [PDF]
, 2022 Seyedesomaye Jasemi +5 more
openalex +1 more source
3D Hydrogel Cell Cultures and Their Biomedical Applications
Advanced NanoBiomed Research, EarlyView.The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai +7 more
wiley +1 more source