Results 61 to 70 of about 109,486 (229)
Complexity of Interferon-γ Interactions with HSV-1 [PDF]
The intricacies involving the role of interferon-gamma (IFN-γ) in herpesvirus infection and persistence are complex. Herpes simplex virus type 1 (HSV-1) uses a variety of receptors to enter cells and is transported to and from the host cell nucleus over the microtubule railroad via retrograde and anterograde transport. IFN-γ exerts dual but conflicting
openaire +5 more sources
Characterization of the murine cytomegalovirus genes encoding the major DNA binding protein and the ICP18.5 homolog [PDF]
In several herpesviruses the genes for the major DNA binding protein (MDBP), a putative assembly protein, the glycoprotein B (gB), and the viral DNA polymerase (pol) coliocate.
Keil, Günther M.+3 more
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Background Herpes simplex virus type 2 (HSV-2) is a major cofactor of human immunodeficiency virus type 1 (HIV-1) sexual acquisition and transmission.
Bélec Laurent+7 more
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HSV-1 causes 50% of first-time genital herpes infections in resource-rich countries and affects 190 million people worldwide. A prophylactic herpes vaccine is needed to protect against genital infections by both HSV-1 and HSV-2. Previously our laboratory
Kevin P Egan+7 more
doaj +1 more source
HSV-1 Ulcers as an Infrequent Cause of Hematochezia
ABSTRACT We report a 62-year-old woman in the intensive care unit who developed hematochezia. Her endoscopic findings revealed diffusely bleeding esophageal ulcers related to herpes simplex virus. The bleeding was treated successfully with Hemospray.
Zarir Ahmed+2 more
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Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis [PDF]
Apoptosis of cytotoxic T lymphocytes by herpes simplex virus type-1 (HSV-1) has been reported to be a relevant mechanism of viral immune evasion. Galectin-1 (Gal-1), an endogenous lectin involved in T-cell apoptosis, has recently gained considerable ...
Gonzalez, Maria Ines+5 more
core +1 more source
Introduction. Herpes simplex virus type 1 (HSV-1) is one of the most common human viral infections and has a double-stranded DNA genome belonging to the Herpesviridae family.
Jalil B. Mays+2 more
doaj +1 more source
Herpes simplex virus infections among rural residents in eastern China
Background Herpes simplex virus (HSV) has two types: HSV-1 and HSV-2. Both infect epithelial cells and establish latent infections in neurons causing an infection that persists for life. Information on age- and gender-specific seroprevalence of HSV-1 and
Chen Li+5 more
doaj +1 more source
Aurintricarboxylic acid increases yield of HSV-1 vectors [PDF]
Production of large quantities of viral vectors is crucial for the success of gene therapy in the clinic. There is a need for higher titers of herpes simplex virus-1 (HSV-1) vectors both for therapeutic use as well as in the manufacturing of clinical grade adeno-associated virus (AAV) vectors.
Hillard Rubin+5 more
openaire +4 more sources
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are among the most common coinfections seen in individuals infected with HIV-1. Most research on HSV-HIV coinfection has focused on HSV-2, and in particular, on its impact on HIV transmission.
Darrell H S Tan+2 more
doaj +1 more source