Results 181 to 190 of about 30,883 (246)

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

Effects of enhanced Melissa officinalis essential oil via carrageenan on mitigating aflatoxin b1-induced cytotoxicity in HT-29 and HEK-293 cells. [PDF]

BMC Complement Med Ther
Ganjali M, Rahimi M, Ramezan D, Mohkami Z, Ranjbary AG, Yamchi A.   +5 more
europepmc   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

Development of a high-throughput UHPLC-MS/MS multi-method for the analysis of mycotoxins in plant-based milk alternatives as the basis for risk assessment. [PDF]

Front Nutr
Dick F, Schuster M, Schneidemann-Bostelmann S, Asam S, Rychlik M.   +4 more
europepmc   +1 more source

Integrating CT‐Based Radiomics Analysis With Serum CEA Level to Predict Neoadjuvant Chemoradiotherapy Response in Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Response to neoadjuvant chemoradiotherapy (NACRT) in locally advanced colorectal cancer (CRC) varies widely, and accurately identifying poor responders is crucial for guiding timely treatment modification. This study aimed to develop an integrated predictive model combining radiomics derived from routine radiotherapy non‐contrast planning ...
Sin‐Hua Moi, Ming‐Yii Huang, Shu‐Han Yang, Chien‐Jang Chen, Ying‐Pei Jhong, Tun‐Wei Hsu, Chien‐Chih Ke   +6 more
wiley   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

The effect of biological control on mycotoxin concentrations and the mycobiome in durum wheat grain and stems. [PDF]

Sci Rep
Wachowska U, Sulyok M, Wiwart M, Suchowilska E, Giedrojć W, Stuper-Szablewska K, Kandler W, Krska R.   +7 more
europepmc   +1 more source

Ear Piercing Complications: Comparing Cartilage and Soft Tissue Piercings in a Large Survey Cohort

The Laryngoscope, EarlyView.
Cartilage ear piercings were associated with significantly higher complication rates than lobule piercings and remained an independent predictor of complications after multivariate analysis. Cartilage site also independently predicted piercing removal, with higher removal rates observed compared to lobule piercings.
John P. Ziegler, Nitin A. Pagedar, McKay Moline, Kathryn Marcus, Zachary G. Tanenbaum, Henry T. Hoffman, Scott R. Owen   +6 more
wiley   +1 more source

<i>Galleria mellonella</i> model recapitulates <i>Staphylococcus aureus</i> hemolysin toxicity and antibody-mediated mechanisms of protection. [PDF]

Front Microbiol
Cherubini E, Mandelli AP, Henrici De Angelis L, Brazzoli M, D'Andrea MM, Bagnoli F, Rossi Paccani S, Chiarot E.   +7 more
europepmc   +1 more source

CardiacDP: An R package for rapid automated cardiac data processing, integrating autocorrelation, a genetic algorithm, and a tracking index

Limnology and Oceanography: Methods, EarlyView.
Abstract Heart rate is a popular proxy of physiological responses, but the highly complex and variable cardiac data obtained from organisms such as marine invertebrates pose a major challenge to efficient and accurate data processing. To address this, we developed a novel, integrative algorithm for rapid and automated cardiac data processing.
Sarah L. Y. Lau, Adrian T. C. Wong, Yi‐Fei Gu, Tin Yan Hui   +3 more
wiley   +1 more source