Results 41 to 50 of about 281 (94)

The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease

Journal of Diabetes Research, Volume 2019, Issue 1, 2019., 2019
Diabetic kidney disease (DKD) is the most common microvascular complication of diabetes and is one of the main causes of end‐stage renal disease (ESRD) in many countries. The pathological features of DKD are the hypertrophy of mesangial cells, apoptosis of podocytes, glomerular basement membrane (GBM) thickening, accumulation of extracellular matrix ...
Zhenzhen Lu, Yifei Zhong, Wangyi Liu, Ling Xiang, Yueyi Deng, Akira Sugawara   +5 more
wiley   +1 more source

Efficacy and Safety of Abelmoschus manihot for Primary Glomerular Disease: A Prospective, Multicenter Randomized Controlled Clinical Trial

, 2014
BackgroundAbelmoschus manihot, a single medicament of traditional Chinese medicine, has been widely used to treat kidney disease. This is the first randomized controlled clinical trial to assess its efficacy and safety in patients with primary glomerular
Zhou, Chun-hua, Wang, Li, Chen, Xiangmei, Ding, Xiao-qiang, Guan, Guang-ju, Hu, Zhao, Zhao, Jiu-yang, Wang, Jian-qin, He, Ya-ni, Zhang, Ai-ping, He, Li-qun, Lin, Shan, Xing, Chang-ying, Liu, Zhang-suo, Chang, Ming, Zhang, Miao, Wu, Xiong-fei, Mei, Chang-lin, Miao, Li-ning, Li, Ping, Zhang, Li, Xie, Ru-juan, Wang, Rong, Lin, Hong-li, Yuan, Fa-huan, Hao, Li, Yin, Ai-ping, Fu, Ping   +27 more
core   +1 more source

Siwu Granules and Erythropoietin Synergistically Ameliorated Anemia in Adenine‐Induced Chronic Renal Failure Rats

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Objective. Renal anemia in patients with end‐stage chronic kidney disease is closely related to the deterioration of cardiac function, renal function, and quality of life. This study involved adenine‐induced renal anemic rat models and evaluated the treatment effect of Siwu granules and/or erythropoietin (EPO). Methods.
Yansheng Wu, Qiang Wan, Liqiang Shi, Jiaoying Ou, YingQiao Li, Fei He, Huiling Wang, Jiandong Gao, Francisco Solano   +8 more
wiley   +1 more source

Clinical efficacy of Huangkui capsules in the treatment of targeted drug-related proteinuria in patients with hepatocellular carcinoma

Zhongguo Linchuang Yixue
ObjectiveTo investigate the therapeutic effect of Huangkui capsules on targeted drug-related proteinuria in patients with hepatocellular carcinoma (HCC).
Miao Li, Jia Yuan, Chu Liu, Maopei Chen, Xin Xu, Ningling Ge, Yi Chen, Lan Zhang, Rongxin Chen, Yan Wang   +9 more
doaj   +1 more source

Traditional Chinese medicine for the treatment of chronic inflammatory diseases: A review of inhibitors for NLRP3 inflammasome

Advanced Chinese Medicine, Volume 2, Issue 1, Page 1-12, March 2025.
Abstract The NLR family pyrin domain‐containing 3 (NLRP3) inflammasome is a vital part of the innate immune response, whilst its aberrant activation drives the progression of several noncommunicable diseases. It induces caspase‐1 activation and the downstream substrates involved with the processing and secretion of the pro‐inflammatory cytokines IL‐1β ...
Yucen Zou, Pei Ma, Bin Li, Jiushi Liu, Lifeng Yue, Bengang Zhang, Haitao Liu   +6 more
wiley   +1 more source

Application of Herbal Medicines with Heat‐Clearing Property to Anti‐Microinflammation in the Treatment of Diabetic Kidney Disease

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Diabetic kidney disease (DKD) is a global pandemic, and microinflammation has been reported as an important pathogenic factor of DKD. Traditional Chinese Medicine (TCM) has been used in the treatment of DKD for thousands of years, and modern Chinese medicine studies have found that herbal medicines with heat‐clearing property have a curative anti ...
Jing Guo, Yabin Gao, Yaoxian Wang, Wei Jing Liu, Jingwei Zhou, Zhen Wang, Pratibha V. Nerurkar   +6 more
wiley   +1 more source

TangNaikang Formula Alleviates Podocyte Injury in Diabetic Nephropathy by Modulating the SHIP2/PI3K/AKT Pathway

Journal of Diabetes Research, Volume 2025, Issue 1, 2025.
Aim This study utilized db/db mice and MPC5 cells induced by high glucose as experimental models to examine the protective mechanisms of the traditional Chinese medicine formula TangNaikang (TNK) in mitigating podocyte injury in diabetic nephropathy (DN).
Tao Yang, Yongxin Huang, Wenjing Li, Lingling Qin, You Wu, Lili Wu, Tonghua Liu, Huantian Cui   +7 more
wiley   +1 more source

Network Pharmacology‐Based Investigation into the Mechanisms of Quyushengxin Formula for the Treatment of Ulcerative Colitis

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Objective. Ulcerative colitis (UC) is a chronic idiopathic inflammatory bowel disease whose treatment strategies remain unsatisfactory. This study aims to investigate the mechanisms of Quyushengxin formula acting on UC based on network pharmacology. Methods.
Haojie Yang, Ying Li, Sichen Shen, Dan Gan, Changpeng Han, Jiong Wu, Zhenyi Wang, Darren R. Williams   +7 more
wiley   +1 more source

Abelmoschus manihot for Diabetic Nephropathy: A Systematic Review and Meta‐Analysis

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Diabetic nephropathy (DN) is the leading cause of end‐stage renal disease (ESRD). Many trials have shown that Abelmoschus manihot could further improve proteinuria and protect kidney function in patients with DN when added to a renin‐angiotensin system (RAS) blocker. A systematic assessment of the efficacy and safety of A.
Liwei Shi, Ling Feng, Meizhen Zhang, Xiaowen Li, Yanan Yang, Yueying Zhang, Qing Ni, Deborah A. Kennedy   +7 more
wiley   +1 more source

Efficacy of Traditional Chinese Medicine Regimen Jian Pi Qu Shi Formula for Refractory Patients with Idiopathic Membranous Nephropathy: A Retrospective Case‐Series Study

Evidence-Based Complementary and Alternative Medicine, Volume 2018, Issue 1, 2018., 2018
Background. The treatment of adult refractory idiopathic membranous nephropathy with steroid and other immunosuppressant‐resistant nephrotic syndromes can be a significant challenge. We evaluated the efficacy and safety of the traditional Chinese medicine Jian Pi Qu Shi Formula (JPQSF) as a promising regimen. Methods.
Bin Shi, Rong-rong Zhang, Ying Liang, Xin-hui Wang, Rui Lang, Ren-huan Yu, Chang G. Son   +6 more
wiley   +1 more source