Total flavonoids of Abelmoschus manihot (L.) medic attenuate early renal injury in diabetic kidney disease by modulating the LINC00665/miR-379-5p axis [PDF]
Pharmaceutical BiologyContext: Huangkui capsule (HKC), derived from Abelmoschus manihot (L.) Medic, is clinically utilized for diabetic kidney disease (DKD) treatment. Its primary bioactive components are the total flavonoids of A. manihot (L.) (TFA).
Nan Li +5 more
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Clinical Efficacy of Huangkui Capsule Plus Methylprednisolone for Immunoglobulin A Nephropathy and Its Effect on Renal Function and Serum Inflammatory Factors. [PDF]
Evid Based Complement Alternat Med, 2023 Objective. To assess the clinical efficacy of Huangkui capsule plus methylprednisolone for immunoglobulin A (IgA) nephropathy and its effect on renal function and serum inflammatory factors. Methods. A total of 80 patients with IgA nephropathy admitted to our hospital from April 2019 to December 2021 were recruited and assigned (1 : 1) to receive ...
Yuan L, Cai K, Zou Y.
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Retracted: Clinical Efficacy of Huangkui Capsule plus Methylprednisolone in the Treatment of Nephropathy and the Effect on Urinary Protein and Serum Inflammatory Factors in Patients. [PDF]
Evid Based Complement Alternat Med, 2023 Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023.
And Alternative Medicine EC.
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Inflammation, Apoptosis, and Fibrosis in Diabetic Nephropathy: Molecular Crosstalk in Proximal Tubular Epithelial Cells and Therapeutic Implications [PDF]
Current Issues in Molecular BiologyDiabetic nephropathy (DN) remains the leading cause of end-stage renal disease worldwide, with proximal tubular epithelial cells (PTECs) playing a central role in its pathogenesis.
Xuanke Liu +5 more
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Huangkui capsules regulate tryptophan metabolism to improve diabetic nephropathy through the Keap1/Nrf2/HO-1 pathway [PDF]
Frontiers in PharmacologyBackgroundDiabetic nephropathy (DN) is a serious complication of diabetes and one of the leading causes of end-stage renal disease. Huangkui capsule (HKC), a traditional Chinese patent medicine, is widely used in clinical practice for the treatment of ...
Jiayu Su +7 more
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Huangkui Capsule Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Macrophage Activation by Suppressing Inflammation and Oxidative Stress in Mice. [PDF]
Evid Based Complement Alternat Med, 2021 Background. Huangkui capsule (HKC) comprises the total flavonoid extract of flowers of Abelmoschus manihot (L.) Medicus. This study aimed to explore the effects of HKC on lipopolysaccharide‐ (LPS‐) induced acute lung injury (ALI) in mice and LPS‐stimulated RAW 264.7 cells. Methods.
Deng J +8 more
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Network pharmacology and molecular docking predictions of the active compounds and mechanism of action of Huangkui capsule for the treatment of idiopathic membranous nephropathy [PDF]
Medicine (United States), 2023 Meng Cai
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Efficacy and safety of Huangkui capsule for diabetic nephropathy A protocol for systematic review and meta-analysis [PDF]
Medicine (Baltimore), 2021 An W +6 more
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Evid Based Complement Alternat Med, 2022 Objective. The study aimed to assess the clinical efficacy of Huangkui capsule plus methylprednisolone in the treatment of nephropathy and the effect on urinary protein and serum inflammatory factors in patients. Methods. Between June 2017 and July 2020, 90 patients with nephropathy admitted to our hospital were recruited after assessment of ...
Wan W +8 more
europepmc +2 more sources
New Insights Into the Effects of Individual Chinese Herbal Medicines on Chronic Kidney Disease
Frontiers in Pharmacology, 2021 The clinical and experimental study into the effects of Chinese herbal medicines on chronic kidney disease has evolved over the past 40 years with new insight into their mechanism and evidence of their clinical effects. Among the many traditional Chinese
Minghai Shao +4 more
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