Results 31 to 40 of about 281 (94)

Shen Qi Wan‐Containing Serum Alleviates Renal Interstitial Fibrosis via Restraining Notch1‐Mediated Epithelial‐Mesenchymal Transition

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Objective. Shen Qi Wan (SQW) is the most classic prescription for the clinical therapy of chronic kidney disease in China. Nevertheless, the function of SQW in renal interstitial fibrosis (RIF) has not been clearly clarified. Our purpose was to explore the protective function of SQW on RIF. Methods. After intervention with SQW‐containing serum alone at
Hongshu Chen   +4 more
wiley   +1 more source

The Effectiveness and Safety of Abelmoschus manihot in Treating IgA Nephropathy: A Systematic Review and Meta‐Analysis

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Introduction. IgA nephropathy (IgAN) is a common issue. In China, Abelmoschus manihot (AM) is widely used in the treatment of IgAN. However, their combined effectiveness and safety for this purpose have not yet been explored. AM is an effective medicine for treating IgAN. This meta‐analysis aimed to evaluate the effectiveness of AM for IgAN.
Qi Jia   +10 more
wiley   +1 more source

Chemical constituents, clinical efficacy and molecular mechanisms of the ethanol extract of Abelmoschus manihot flowers in treatment of kidney diseases

open access: yesPhytotherapy Research, Volume 35, Issue 1, Page 198-206, January 2021., 2021
Abelmoschus manihot, also called as “Huangkui” in Chinese, is an annual flowering herb plant in the family of Malvaceae. As a traditional Chinese medicine, the ethanol extract of the flower in Abelmoschus manihot is made as Huangkui capsule and has been used for medication of the patients with kidney diseases.
Nan Li   +8 more
wiley   +1 more source

What was new at the 2023 American Diabetes Association meeting?

open access: yes, 2023
Journal of Diabetes, Volume 15, Issue 8, Page 636-639, August 2023.
Zachary Bloomgarden
wiley   +1 more source

DataSheet1_Evaluation of the efficacy of Abelmoschus manihot (L.) on diabetic nephropathy by analyzing biomarkers in the glomeruli and proximal and distal convoluted tubules of the kidneys.PDF

open access: yes, 2023
Introduction: As a traditional Chinese medicine, Abelmoschus manihot (L.) in the form of Huangkui (HK) capsule has been used as a medication for kidney diseases, including diabetic nephropathy (DN), in China.
Haitao Tang   +23 more
core   +1 more source

Hyperoside Alleviates High Glucose‐Induced Proliferation of Mesangial Cells through the Inhibition of the ERK/CREB/miRNA‐34a Signaling Pathway

open access: yesInternational Journal of Endocrinology, Volume 2020, Issue 1, 2020., 2020
Purpose. Hyperoside, a flavonoid isolated from conventional medicinal herbs, has been demonstrated to exert a significant protective effect in diabetic nephropathy. This study aimed to determine the underlying mechanisms, by which hyperoside inhibits high glucose‐(HG‐) induced proliferation in mouse renal mesangial cells. Methods.
Le Zhang   +9 more
wiley   +1 more source

Comparative efficacy of seven Chinese patent medicines for early diabetic kidney disease: A Bayesian network meta-analysis

open access: yesComplementary Therapies in Medicine, 2022
Background: Bailing Capsule (BLC), Jinshuibao (JSB), Huangkui Capsule (HKC), Uremic Clearance Granule (UCG), Tripterygium glycosides (TG), Compound Xueshuantong Capsule (CXC), and Shenyan Kangfu Tablet (SYKFT) as classic Chinese patent medicines (CPMs ...
Jie Zhao   +4 more
doaj   +1 more source

Mechanisms of Herbal Nephroprotection in diabetes mellitus

open access: yesJournal of Diabetes Research, Volume 2020, Issue 1, 2020., 2020
Diabetic nephropathy (DN) is a leading cause of kidney morbidity. Despite the multilayered complexity of the mechanisms involved in the pathogenesis of DN, the conventional treatment is limited to just a few drug classes fraught with the risk of adverse events, including the progression of renal dysfunction. Phytoceuticals offer a promising alternative
Dorin Dragoș   +4 more
wiley   +1 more source

Integrating the Polydopamine Nanosphere/Aptamers Nanoplatform with a DNase-I-Assisted Recycling Amplification Strategy for Simultaneous Detection of MMP‑9 and MMP‑2 during Renal Interstitial Fibrosis

open access: yes, 2020
Matrix metalloproteinase-9 (MMP-9) and matrix metalloproteinase-2 (MMP-2) play important roles in the progression of renal interstitial fibrosis (RIF). There is an increasing demand to construct a novel method for the simultaneous detection of MMP-9 and ...
Ran Zhang   +19 more
core   +1 more source

Clinical effect of Jinhu Gushen prescription in reducing urinary protein and blood uric acid in patients with diabetic kidney disease [PDF]

open access: yes精准医学杂志
Objective To investigate the clinical effect of Jinhu Gushen prescription in the treatment of diabetic kidney disease (DKD). Methods A retrospective cohort study was conducted among 157 patients with DKD who were admitted to Department of Endocrinology ...
LI Yixuan, HUANG Yajing, WEI Fanxiang, LI Wenxuan, XU Lili, WANG Yangang
doaj   +1 more source

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