Results 61 to 70 of about 100,698 (279)
SWIM: A computational tool to unveiling crucial nodes in complex biological networks [PDF]
, 2017 SWItchMiner (SWIM) is a wizard-like software implementation of a procedure, previously described, able to extract information contained in complex networks.
Colombo, Teresa +5 more
core +2 more sources
Network Analyses of Differentially Expressed Genes in Osteoarthritis to Identify Hub Genes [PDF]
BioMed Research International, 2019 Background. Osteoarthritis (OA) is the most common degenerative disease in orthopedics. However, the cause and underlying molecular mechanisms are not clear. This study aims to identify the hub genes and pathways involved in the occurrence of osteoarthritis. Methods.
Zhaoyan Li +8 more
openaire +2 more sources
Identification and validation of hub genes for diabetic retinopathy
PeerJ, 2021 Background Diabetic retinopathy (DR) is characterized by a gradually progressive alteration in the retinal microvasculature that leads to middle-aged adult acquired persistent blindness. Limited research has been conducted on DR pathogenesis at the gene level.
Li Peng, Wei Ma, Qing Xie, Baihua Chen
openaire +3 more sources
Identification of hub genes related to prognosis in glioma [PDF]
Bioscience Reports, 2020 Abstract Glioma, a common malignant tumor of the central nervous system, has high invasiveness. The objective of the present study was to identify genes playing an important role in the development of glioma and to reveal their potential research value.
Delong Zhang +5 more
openaire +2 more sources
Discover Oncology, 2022 Prostate cancer (PCa) and benign prostate hyperplasia (BPH) are commonly encountered diseases in males. Studies showed that genetic factors are responsible for the occurrences of both diseases.
Xi Chen +9 more
doaj +1 more source
Informatics in Medicine Unlocked, 2023 Objective: Although recent studies have focused on the role of genes in the pathogenesis of endometriosis, the investigation of genes and molecular pathways involved in the pathogenesis of endometriosis with a bioinformatics approach has not been ...
Mahin Khalilzadeh Seivani +5 more
doaj +1 more source
The pros and comms of gene sequencing [PDF]
, 2017 Full-gene sequencing undoubtedly comes with its pluses and its minuses. In this article, the authors aim to weigh up the pros and cons not only from the point of view of the patient but also in view of the doctor's possible perspective.
Codacci Pisanelli, Giovanni +3 more
core +2 more sources
Identification of Immune-Related Hub Genes in Parkinson’s Disease
Frontiers in Genetics, 2022 Background: Parkinson’s disease (PD) is a common, age-related, and progressive neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an essential role in the pathogenic process of PD. The objective of this study was to explore potential immune-related hub genes and immune infiltration patterns of PD.Method: The microarray ...
Lin Chen +4 more
openaire +3 more sources
Significance of hub genes and immune cell infiltration identified by bioinformatics analysis in pelvic organ prolapse [PDF]
PeerJ, 2020 Objective Pelvic organ prolapse (POP) refers to the decline of pelvic organ position and dysfunction caused by weak pelvic floor support. The aim of the present study was to screen the hub genes and immune cell infiltration related to POP disease ...
Ying Zhao +3 more
doaj +2 more sources
Hub-Centered Gene Network Reconstruction Using Automatic Relevance Determination
PLoS ONE, 2012 Network inference deals with the reconstruction of biological networks from experimental data. A variety of different reverse engineering techniques are available; they differ in the underlying assumptions and mathematical models used. One common problem for all approaches stems from the complexity of the task, due to the combinatorial explosion of ...
M. Böck +4 more
openaire +4 more sources