Results 121 to 130 of about 122,515 (310)
Advanced Science, EarlyView.This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source
Advanced Science, EarlyView.SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley +1 more source
Advanced Biomedical Research, 2012 Background: There are significant limitations in repair of irrecoverable bone defects. Stem-cell therapy is a promising approach for the construction of bone tissue.
Vahid Bahrambeigi +3 more
doaj +1 more source
Investigations into the in vitro developmental plasticity of adult mesenchymal stem cells [PDF]
, 2006 Bone marrow (BM) derived stem cells contribute to the regeneration of diverse adult tissues including heart, liver and brain following BM transplantation.
Croft, Adam P., Croft, Adam P
core
, 2017 Background aims. Adipose-derived stem cells (ASCs) represent an important source of cell therapy to treat diabetic complications. However, hyperglycemia may alter several cellular functions, so the present study aimed to investigate the influence of a ...
Cheng, Nai-Chen;Hsieh, Tsung-Yu;Lai, Hong-Shiee;Young, Tai-Horng +1 more
core +1 more source
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Advanced Science, EarlyView.Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
Characteristics and Properties of Mesenchymal Stem Cells Derived from Microfragmented Adipose Tissue
Cell Transplantation, 2015 The subcutaneous adipose tissue provides a clear advantage over other mesenchymal stem cell sources due to the ease with which it can be accessed, as well as the ease of isolating the residing stem cells.
Stephana Carelli +11 more
doaj +1 more source
Triggering the activation of Activin A type II receptor in human adipose stem cells towards tenogenic commitment using mechanomagnetic stimulation [PDF]
, 2018 Stem cell therapies hold potential to stimulate tendon regeneration and homeostasis, which is maintained in response to the native mechanical environment.
core +1 more source
Advanced Science, EarlyView.Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim +2 more
wiley +1 more source
Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues
Advanced Science, EarlyView.Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self‐assembling vasculature, extracellular matrix deposition, and angiogenic responses, thereby establishing critical acoustic patterning requirements for engineered vascular tissue development in ...
Oscar O'Dwyer Lancaster‐Jones +5 more
wiley +1 more source