Results 41 to 50 of about 119,573 (312)

Physiopathology and Organotypic Cultures of Human Keratinocytes [PDF]

Dermatology, 2009
info:eu-repo/semantics ...
openaire   +3 more sources

Nickel Nanoparticles Induce the Synthesis of a Tumor-Related Polypeptide in Human Epidermal Keratinocytes

Nanomaterials, 2020
Although nickel allergy and carcinogenicity are well known, their molecular mechanisms are still uncertain, thus demanding studies at the molecular level.
Javier Jiménez-Lamana, Simon Godin, Gerard Aragonès, Cinta Bladé, Joanna Szpunar, Ryszard Łobinski   +5 more
doaj   +1 more source

Transcriptional Network of p63 in Human Keratinocytes

PLoS ONE, 2009
p63 is a transcription factor required for the development and maintenance of ectodermal tissues in general, and skin keratinocytes in particular. The identification of its target genes is fundamental for understanding the complex network of gene regulation governing the development of epithelia.
S. Pozzi, F. Zambelli, D. Merico, G. Pavesi, A. Robert, P. Maltère, X. Gidrol, R. Mantovani, M.A. Viganò   +8 more
openaire   +4 more sources

EpCAM Induction Functionally Links to the Wnt-Enhanced Cell Proliferation in Human Keratinocytes

Cell Transplantation, 2014
Accelerating proliferation of primary keratinocytes benefits skin autografts for severely burned patients. Wnt signal, a conserved pathway controlling cell cycle and morphogenesis in embryo, also involves in cell proliferation and tumorigenesis in adult ...
Ching-I Shen, Hsiu-Chin Lee, Ying-Hsien Kao, Chieh-Shan Wu, Po-Hung Chen, Shinn-Zong Lin, Ping-Shan Lai, Hong-Lin Su   +7 more
doaj   +1 more source

Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity [PDF]

, 2014
A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established
van den Hurk, Corina J., Komen, Manon M., Hussain, Omar, Dunnill, Christopher, Georgopoulos, Nikolaos T., Al-Tameemi, Wafaa, Collett, Andrew   +6 more
core   +1 more source

Human beta-defensin 3 is up-regulated in cutaneous leprosy type 1 reactions. [PDF]

, 2012
BACKGROUND: Leprosy, a chronic granulomatous disease affecting the skin and nerves, is caused by Mycobacterium leprae (M. leprae). The type of leprosy developed depends upon the host immune response.
Chrissy H Roberts, Walker Stephen L., Deanna A Hagge, Anna L Cogen, Diana N J Lockwood, Deanna A. Hagge, Stephen L. Walker, Anna L. Cogen, Kapil D. Neupane, Neupane, Kapil D, Diana N. J. Lockwood, Lockwood, Diana NJ, Neupane Kapil D., Khadge, Saraswoti, Walker, Stephen L, Kapil D Neupane, Hagge, Deanna A, Cogen Anna L., Saraswoti Khadge, Stephen L Walker, Roberts Chrissy H., Lockwood Diana N. J., Hagge Deanna A., Khadge Saraswoti, Roberts, Chrissy H, Cogen, Anna L, Chrissy H. Roberts   +26 more
core   +1 more source

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +1 more source

Human Basal and Suprabasal Keratinocytes Are Both Able to Generate and Maintain Dermo–Epidermal Skin Substitutes in Long-Term In Vivo Experiments

Cells, 2022
The basal layer of human interfollicular epidermis has been described to harbour both quiescent keratinocyte stem cells and a transit amplifying cell population that maintains the suprabasal epidermal layers.
Luca Pontiggia, Akshay Kumar Ahuja, Hesham Kamaleldin Yosef, Dominic Rütsche, Ernst Reichmann, Ueli Moehrlen, Thomas Biedermann   +6 more
doaj   +1 more source

Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis [PDF]

, 2009
Antimicrobial peptides (AMPs) are strongly expressed in lesional skin in psoriasis and play an important role as proinflammatory "alarmins" in this chronic skin disease.
Koglin, Sarah, Ulrich Zügel, Thomas Ruzicka, Büchau Amanda, Dombrowski, Yvonne, Zügel, Ulrich, Steinmeyer, Andreas, Jürgen Schauber, Schauber, Jürgen, Büchau, Amanda, Sarah Koglin, Steinmeyer Andreas, Bradac, Eva, Mark Peric, Schauber Jürgen, Koglin Sarah, Amanda Büchau, Zügel Ulrich, Yvonne Dombrowski, Eva Bradac, Katrin Gross, Peric Mark, Gross, Katrin, Dombrowski Yvonne, Peric, Mark, Andreas Steinmeyer, Dombrowski, Yvonne; id_orcid, Bradac Eva, Groß Katrin, Ruzicka, Thomas, Ruzicka Thomas   +30 more
core   +1 more source

Protective Effects of Violaxanthin on Cellular Oxidative Stress via NRF2 Activation in H₂O₂-Stimulated Human Keratinocytes

Applied Sciences
Excessive accumulation of reactive oxygen species from exogenous and endogenous stressors can cause cellular damage. Chlorella contains diverse bioactive compounds, and violaxanthin, a major carotenoid pigment found in Chlorella sp.
Ji-Seon Kim, Hee Su Kim, Hee-Jae Shin, Seokmuk Park, Ji Won Kim, Su-Bin Park, Hee-Sik Kim, Yong Jae Lee, Seunghee Bae   +8 more
doaj   +1 more source