Results 31 to 40 of about 102,593 (165)

Human Basal and Suprabasal Keratinocytes Are Both Able to Generate and Maintain Dermo–Epidermal Skin Substitutes in Long-Term In Vivo Experiments

open access: yesCells, 2022
The basal layer of human interfollicular epidermis has been described to harbour both quiescent keratinocyte stem cells and a transit amplifying cell population that maintains the suprabasal epidermal layers.
Luca Pontiggia   +6 more
doaj   +1 more source

Catecholamines in Human Keratinocyte Differentiation

open access: yesJournal of Investigative Dermatology, 1995
Human keratinocytes have the capacity to synthesize catecholamines from L-tyrosine, which in turn is produced from L-phenylalanine via phenylalanine hydroxylase. This enzyme activity is controlled by the supply of the essential cofactor/electron donor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4).
Schallreuter, Karin U.   +5 more
openaire   +2 more sources

Graphene Nanoplatelets: In Vivo and In Vitro Toxicity, Cell Proliferative Activity, and Cell Gene Expression

open access: yesApplied Sciences, 2022
Multi-layer graphene (2–10 layers), also called graphene nanoplatelets (GNPs), is a carbon-based nanomaterial (CBN) type with excellent properties desirable for many biomedical applications.
Beatriz Salesa   +5 more
doaj   +1 more source

Nickel Nanoparticles Induce the Synthesis of a Tumor-Related Polypeptide in Human Epidermal Keratinocytes

open access: yesNanomaterials, 2020
Although nickel allergy and carcinogenicity are well known, their molecular mechanisms are still uncertain, thus demanding studies at the molecular level.
Javier Jiménez-Lamana   +5 more
doaj   +1 more source

EpCAM Induction Functionally Links to the Wnt-Enhanced Cell Proliferation in Human Keratinocytes

open access: yesCell Transplantation, 2014
Accelerating proliferation of primary keratinocytes benefits skin autografts for severely burned patients. Wnt signal, a conserved pathway controlling cell cycle and morphogenesis in embryo, also involves in cell proliferation and tumorigenesis in adult ...
Ching-I Shen   +7 more
doaj   +1 more source

Comparative Evaluation of Different Chitosan Species and Derivatives as Candidate Biomaterials for Oxygen-Loaded Nanodroplet Formulations to Treat Chronic Wounds

open access: yesMarine Drugs, 2021
Persistent hypoxia is a main clinical feature of chronic wounds. Intriguingly, oxygen-loaded nanodroplets (OLNDs), filled with oxygen-solving 2H,3H-decafluoropentane and shelled with polysaccharides, have been proposed as a promising tool to counteract ...
Monica Argenziano   +11 more
doaj   +1 more source

Transcriptional Network of p63 in Human Keratinocytes

open access: yesPLoS ONE, 2009
p63 is a transcription factor required for the development and maintenance of ectodermal tissues in general, and skin keratinocytes in particular. The identification of its target genes is fundamental for understanding the complex network of gene regulation governing the development of epithelia.
S. Pozzi   +8 more
openaire   +4 more sources

Protective Effects of Violaxanthin on Cellular Oxidative Stress via NRF2 Activation in H2O2-Stimulated Human Keratinocytes

open access: yesApplied Sciences
Excessive accumulation of reactive oxygen species from exogenous and endogenous stressors can cause cellular damage. Chlorella contains diverse bioactive compounds, and violaxanthin, a major carotenoid pigment found in Chlorella sp.
Ji-Seon Kim   +8 more
doaj   +1 more source

Locomotion of Human Skin Keratinocytes on Polystyrene, Fibrin, and Collagen Substrata and its Modification by Cell-to-Cell Contacts

open access: yesCell Transplantation, 2001
Epithelial wound repair assures the recovery of the epithelial barrier after wounding. During wound healing epithelial cells migrate to cover the wound surface.
Justyna Drukala Ph.D.   +3 more
doaj   +1 more source

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