Results 31 to 40 of about 119,573 (312)
Frontiers in Pharmacology, 2022 Mupirocin has been reported for its role in the treatment of infected wounds through its antibacterial activity, however the role of mupirocin in promoting wound healing via alternative mechanisms has not been extensively evaluated.
Danielle Twilley +6 more
doaj +1 more source
Acta Dermato-Venereologica, 2020 To evaluate cellular response to oncostatin M (OSM) in comparison to interleukin (IL)-31, we analyzed monocyte chemoattractant protein 1 (MCP-1) as a readout for OSM responses with and without IL-4, IL-13, anti-OSM receptor β monoclonal antibody KPL-716,
Carl D. Richards +4 more
doaj +1 more source
Applied Sciences, 2022 Multi-layer graphene (2–10 layers), also called graphene nanoplatelets (GNPs), is a carbon-based nanomaterial (CBN) type with excellent properties desirable for many biomedical applications.
Beatriz Salesa +5 more
doaj +1 more source
Catecholamines in Human Keratinocyte Differentiation
Journal of Investigative Dermatology, 1995 Human keratinocytes have the capacity to synthesize catecholamines from L-tyrosine, which in turn is produced from L-phenylalanine via phenylalanine hydroxylase. This enzyme activity is controlled by the supply of the essential cofactor/electron donor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4).
Schallreuter, Karin U. +5 more
openaire +2 more sources
Molecular Oncology, 2016 The activation status of the insulin‐like growth factor‐1 receptor (IGF‐1R) regulates the cellular response of keratinocytes to ultraviolet B (UVB) exposure, both in vitro and in vivo.
Mathew M. Loesch +7 more
doaj +1 more source
Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin [PDF]
, 1996 The cornified envelope is a layer of transglutaminase cross-linked protein that is deposited under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Dooley, TP +9 more
core +1 more source
Antioxidants, 2021 5-Fluorouracil (5-FU) is a pyrimidine analogue used as an antineoplastic agent to treat multiple solid tumors. Despite its use and efficacy, it also has important side effects in healthy cells, including skin reactions, related to its pro-oxidant and pro-
Shara Francesca Rapa +6 more
doaj +1 more source
Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo [PDF]
, 2004 In gene therapy, a clinically relevant therapeutic effect requires long-term expression of the desired gene at a level sufficient to correct or at least alleviate the underlying gene defect.
Pfützner, Wolfgang, Vogel, Jonathan C.
core +1 more source
Marine Drugs, 2021 Persistent hypoxia is a main clinical feature of chronic wounds. Intriguingly, oxygen-loaded nanodroplets (OLNDs), filled with oxygen-solving 2H,3H-decafluoropentane and shelled with polysaccharides, have been proposed as a promising tool to counteract ...
Monica Argenziano +11 more
doaj +1 more source
Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes [PDF]
, 2010 Background The human cell cycle transcription factor FOXM1 is known to play a key role in regulating timely mitotic progression and accurate chromosomal segregation during cell division.
Chaplin Tracy +14 more
core +1 more source