Results 11 to 20 of about 7,596,165 (249)

Cortisol synthesis by primary human keratinocytes [PDF]

, 2009
PhDCortisol analogues have been used to treat skin disorders, such as psoriasis and atopic dermatitis, for over 50 years but the ability of normal human keratinocytes to synthesise cortisol has not been reported.
Hannen, Rosalind Francesca
core   +4 more sources

Characterisation of apoptotic responses in human keratinocytes expressnig alpha-6 integrin and CD44 [PDF]

, 2010
PhDa6 integrin has previously been proposed as a human keratinocyte stem cell markers. CD44-positive cells in epithelial tumours have been identified as potential cancer stem cells (CSCs) and display increased survival following chemotherapy ...
Wray, Helen
core   +4 more sources

The role of GLI2 in human basal cell carcinoma tumourigenesis [PDF]

, 2010
PhDAbnormal Sonic Hedgehog (SHH) signalling leads to increased transcriptional activation of its downstream effector, GLI2, which is implicated in the pathogenesis of a variety of human tumours, including human basal cell carcinoma (BCC).
Pantazi, Eleni
core   +4 more sources

Differential and Overlapping Effects of Melatonin and Its Metabolites on Keratinocyte Function: Bioinformatics and Metabolic Analyses

Antioxidants, 2021
We investigated the effects of melatonin and its selected metabolites, i.e., N1-Acetyl-N2-formyl-5-methoxykynurenamine (AFMK) and 6-hydroxymelatonin (6(OH)Mel), on cultured human epidermal keratinocytes (HEKs) to assess their homeostatic activities with ...
Joanna Stefan, Tae-Kang Kim, Fiona Schedel, Zorica Janjetovic, David K. Crossman, Kerstin Steinbrink, Radomir M. Slominski, Jaroslaw Zmijewski, Meri K. Tulic, Russel J. Reiter, Konrad Kleszczyński, Andrzej T. Slominski   +11 more
doaj   +1 more source

In Vitro Cytotoxicity and Phototoxicity Assessment of Acylglutamate Surfactants Using a Human Keratinocyte Cell Line

Cosmetics, 2014
In the current study, human keratinocyte cell line was used as in vitro cell culture model to elucidate the effects of the fatty acid chain length of acylglutamate (amino acid-based surfactant) namely, sodium cocoyl glutamate, sodium lauroyl glutamate ...
Abhay Kyadarkunte, Milind Patole, Varsha Pokharkar   +2 more
doaj   +1 more source

Antioxidant and Pro-Oxidant Capacities as Mechanisms of Photoprotection of Olive Polyphenols on UVA-Damaged Human Keratinocytes

Molecules, 2021
A wide variety of polyphenols are reported to have considerable antioxidant and skin photoprotective effects, although the mechanisms of action are not fully known.
Raffaella Marina Lecci, Isabella D’Antuono, Angela Cardinali, Antonella Garbetta, Vito Linsalata, Antonio F. Logrieco, Antonella Leone   +6 more
doaj   +1 more source

Gibberellic Acid Initiates ER Stress and Activation of Differentiation in Cultured Human Immortalized Keratinocytes HaCaT and Epidermoid Carcinoma Cells A431

Pharmaceutics, 2021
Diterpenoid plant hormone gibberellic acid (GA) plays an important role in regulation of plant growth and development and is commonly used in agriculture for activation of plant growth and food production.
Mariya Vildanova, Polina Vishnyakova, Aleena Saidova, Victoria Konduktorova, Galina Onishchenko, Elena Smirnova   +5 more
doaj   +1 more source

The anti-inflammatory and analgesic potential of the probiotic Streptococcus thermophilus via inhibition of endocannabinoid-degrading enzymes: a preliminary in vitro study [PDF]

Exploration of Immunology
Aim: The benefit of topical application of probiotics on pain and itching associated with skin disorders has become an increasingly intriguing topic in recent years.
Serena Altamura, Elona Dybeli, Francesca Lombardi, Paola Palumbo, Francesca Rosaria Augello, Skender Topi, Maria Grazia Cifone, Benedetta Cinque   +7 more
doaj   +1 more source

OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

Antioxidants, 2022
Olfactory receptors (ORs) are the largest protein superfamily in mammals. Certain ORs are ectopically expressed in extranasal tissues and regulate cell type-specific signal transduction pathways. OR2AT4 is ectopically expressed in skin cells and promotes
Ji-Sun Kim, Ha Lim Lee, Ji Hyun Jeong, Ye Eun Yoon, In-Ryeong Lee, Ji Min Kim, Chunyan Wu, Sung-Joon Lee   +7 more
doaj   +1 more source

Chitin modulates innate immune responses of keratinocytes. [PDF]

, 2011
Chitin, after cellulose the second most abundant polysaccharide in nature, is an essential component of exoskeletons of crabs, shrimps and insects and protects these organisms from harsh conditions in their environment.
Korting, Hans Christian, Koller, Barbara, Thomas Ruzicka, Korting Hans Christian, Rupec Rudolph, Müller-Wiefel Alisa Sophie, Alisa Sophie Müller-Wiefel, Müller-Wiefel, Alisa Sophie, Rudolph Rupec, Koller Barbara, Hans Christian Korting, Ruzicka, Thomas, Barbara Koller, Ruzicka Thomas, Rupec, Rudolph   +14 more
core   +2 more sources