Results 1 to 10 of about 119,573 (312)

Human keratinocytes are vanilloid resistant. [PDF]

PLoS ONE, 2008
BACKGROUND: Use of capsaicin or resiniferatoxin (RTX) as analgesics is an attractive therapeutic option. RTX opens the cation channel inflammatory pain/vanilloid receptor type 1 (TRPV1) permanently and selectively removes nociceptive neurons by Ca(2 ...
László Pecze, Kornélia Szabó, Márta Széll, Katalin Jósvay, Krisztián Kaszás, Erzsébet Kúsz, Tamás Letoha, János Prorok, István Koncz, András Tóth, Lajos Kemény, Csaba Vizler, Zoltán Oláh   +12 more
doaj   +7 more sources

Retinoic acid induces hyaluronic acid production through the klotho-mediated EGFR signaling pathway in human epidermal keratinocytes [PDF]

Archives of Biological Sciences, 2022
All-trans retinoic acid (RA) is an effective anti-aging chemical substance widely used in skin-care products. RA compromises epidermal differentiation and induces keratinocyte proliferation, causing hyaluronic acid production through mechanisms that are ...
Choi Hyangtae, Lee Yonghee, Park Won-seok, Kim Beom Joon, Lee Chang Seok   +4 more
doaj   +1 more source

Ethanol Extract of Yak-Kong Fermented by Lactic Acid Bacteria from a Korean Infant Markedly Reduces Matrix Metallopreteinase-1 Expression Induced by Solar Ultraviolet Irradiation in Human Keratinocytes and a 3D Skin Model

Antioxidants, 2021
Yak-Kong is a type of black soybean that is colloquially referred to as the “medicinal bean” and it elicits several beneficial effects that are relevant to human health, including attenuating the formation of skin wrinkles.
Heanim Park, Ji Won Seo, Tae Kyung Lee, Jae Hwan Kim, Jong-Eun Kim, Tae-Gyu Lim, Jung Han Yoon Park, Chul Sung Huh, Hee Yang, Ki Won Lee   +9 more
doaj   +1 more source

Expression of Retinal G Protein-Coupled Receptor, a Member of the Opsin Family, in Human Skin Cells and Its Mediation of the Cellular Functions of Keratinocytes

Frontiers in Cell and Developmental Biology, 2022
Background: Photoreceptive proteins play critical physiological roles in human skin cells. The retinal G protein-coupled receptor (RGR) is a photoisomerase in the human retina, but its expression and cellular functions in human skin cells have not been ...
Yangguang Gu, Yangguang Gu, Yu Wang, Yu Wang, Yinghua Lan, Yinghua Lan, Jianglong Feng, Jianglong Feng, Wen Zeng, Wen Zeng, Wei Zhang, Wei Zhang, Hongguang Lu, Hongguang Lu   +13 more
doaj   +1 more source

Lactoplantibacillus plantarum KG Lysates Inhibit the Internalization of Staphylococcus aureus by Human Keratinocytes through the Induction of Human Beta-Defensin 3

Applied Sciences, 2022
Human β-defensin 3 (hBD3) is an antimicrobial peptide and a chemoattractant molecule expressed in human keratinocytes. Lysates prepared from Lactoplantibacillus plantarum KG (KG lysates), a fermented lactobacillus strain with Ginseng extracts ...
Kyoung-Ok Jang, Chaeyeon Yu, Hangeun Kim, Dae-Kyun Chung   +3 more
doaj   +1 more source

Remifentanil protects human keratinocytes against hypoxia-reoxygenation injury through activation of autophagy. [PDF]

PLoS ONE, 2015
The proliferation, differentiation, and migration of keratinocytes are essential in the early stages of wound healing. Hypoxia-Reoxygenation (H/R) injury to keratinocytes can occur in various stressful environments such as surgery, trauma, and various ...
Jae-Young Kwon, Bong-Soo Park, Yong-Ho Kim, Yong-Deok Kim, Cheul-Hong Kim, Ji-Young Yoon, Ji-Uk Yoon   +6 more
doaj   +1 more source

Protective Effect of Merbau (Intsia bijuga) Extract on Hydrogen Peroxide-Treated HaCaT Human Keratinocytes and Its Formulation as Antioxidant Cream [PDF]

Pharmaceutical Sciences, 2021
Background: The excessive generation of ROS in the skin results in oxidative stress that can contribute to premature skin aging, inflammation, and skin carcinogenesis. To prevent these detrimental effects, the development of herbal medicine with a potent
Leonny Yulita Hartiadi, Agnes Anania Triavika sahamastuti, Cynthia Valentina Chandra, Erlina Febriani, Shakila Angyaja Adiyanto, Giovanni Batista Christian Daeli, Gabriella Cindy Clarissa   +6 more
doaj   +1 more source

Carbon Nanofibers versus Silver Nanoparticles: Time-Dependent Cytotoxicity, Proliferation, and Gene Expression

Biomedicines, 2021
Carbon nanofibers (CNFs) are one-dimensional nanomaterials with excellent physical and broad-spectrum antimicrobial properties characterized by a low risk of antimicrobial resistance.
Beatriz Salesa, Marcelo Assis, Juan Andrés, Ángel Serrano-Aroca   +3 more
doaj   +1 more source

Human Keratinocytes Inhibit CD4⁺ T-Cell Proliferation through TGFB1 Secretion and Surface Expression of HLA-G1 and PD-L1 Immune Checkpoints

Cells, 2021
Human skin protects the body against infection and injury. This protection involves immune and epithelial cells, but their interactions remain largely unknown.
Guillaume Mestrallet, Frédéric Auvré, Chantal Schenowitz, Edgardo D. Carosella, Joel LeMaoult, Michèle T. Martin, Nathalie Rouas-Freiss, Nicolas O. Fortunel   +7 more
doaj   +1 more source

Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities

PAIN Reports, 2016
. Introduction: Epidermal keratinocytes are increasingly recognized as active participants in the sensory transduction of itch and pain, processes known to involve primary afferent glutamatergic neurons.
David Cabañero, Takeshi Irie, Marta Celorrio, Christopher Trousdale, David M. Owens, David Virley, Phillip J. Albrecht, Michael J. Caterina, Frank L. Rice, Jose A. Morón   +9 more
doaj   +1 more source