Results 1 to 10 of about 102,593 (165)
Human keratinocytes are vanilloid resistant. [PDF]
PLoS ONE, 2008 BACKGROUND: Use of capsaicin or resiniferatoxin (RTX) as analgesics is an attractive therapeutic option. RTX opens the cation channel inflammatory pain/vanilloid receptor type 1 (TRPV1) permanently and selectively removes nociceptive neurons by Ca(2 ...
László Pecze +12 more
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Bioelectric characterization of senescing human keratinocytes. [PDF]
iScienceAging, a ubiquitous process that affects almost all multicellular organisms, is accompanied by the accumulation of senescent cells, leading to a decline of morphology and function. The ‘loss of morphostatic information’ theory posits that aging occurs due to gradual breakdown of order initially established during embryo development. Spatial differences
Sediqi H, Levin M.
europepmc +4 more sources
Antioxidant Activities and Mechanisms of Tomentosin in Human Keratinocytes
Antioxidants, 2022 Tomentosin, one of natural sesquiterpene lactones sourced from Inula viscosa L., exerts therapeutic effects in various cell types. Here, we investigated the antioxidant activities and the underlying action mechanisms of tomentosin in HaCaT cells (a human
Seyoung Yang +11 more
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Antioxidants, 2021 5-Fluorouracil (5-FU) is a pyrimidine analogue used as an antineoplastic agent to treat multiple solid tumors. Despite its use and efficacy, it also has important side effects in healthy cells, including skin reactions, related to its pro-oxidant and pro-
Shara Francesca Rapa +6 more
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Retinoic acid induces hyaluronic acid production through the klotho-mediated EGFR signaling pathway in human epidermal keratinocytes [PDF]
Archives of Biological Sciences, 2022 All-trans retinoic acid (RA) is an effective anti-aging chemical substance widely used in skin-care products. RA compromises epidermal differentiation and induces keratinocyte proliferation, causing hyaluronic acid production through mechanisms that are ...
Choi Hyangtae +4 more
doaj +1 more source
Antioxidants, 2021 Yak-Kong is a type of black soybean that is colloquially referred to as the “medicinal bean” and it elicits several beneficial effects that are relevant to human health, including attenuating the formation of skin wrinkles.
Heanim Park +9 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Background: Photoreceptive proteins play critical physiological roles in human skin cells. The retinal G protein-coupled receptor (RGR) is a photoisomerase in the human retina, but its expression and cellular functions in human skin cells have not been ...
Yangguang Gu +13 more
doaj +1 more source
Transport of Biotin in Human Keratinocytes [PDF]
Journal of Investigative Dermatology, 2003 Biotin is an essential micronutrient for normal cellular function, growth, and development. Biotin deficiency leads to pathologic, dermatologic, and neurocutaneous manifestations in skin and its appendages. Previous studies described the presence of specific biotin transport systems in the epithelia of the intestine, liver, kidney, and placenta, and in
Grafe, Franziska +3 more
openaire +2 more sources
Applied Sciences, 2022 Human β-defensin 3 (hBD3) is an antimicrobial peptide and a chemoattractant molecule expressed in human keratinocytes. Lysates prepared from Lactoplantibacillus plantarum KG (KG lysates), a fermented lactobacillus strain with Ginseng extracts ...
Kyoung-Ok Jang +3 more
doaj +1 more source
Remifentanil protects human keratinocytes against hypoxia-reoxygenation injury through activation of autophagy. [PDF]
PLoS ONE, 2015 The proliferation, differentiation, and migration of keratinocytes are essential in the early stages of wound healing. Hypoxia-Reoxygenation (H/R) injury to keratinocytes can occur in various stressful environments such as surgery, trauma, and various ...
Jae-Young Kwon +6 more
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