Results 81 to 90 of about 23,184 (172)

Association of human telomerase reverse transcriptase promoter mutation with unfavorable prognosis in glioma: A systematic review and meta-analysis. [PDF]

J Res Med Sci, 2023
Hua R, Li Q, Gao H, Wang B, He C, Wang Y, Zhang S, Gao L, Shang H, Wang W, Xu J.   +10 more
europepmc   +1 more source

Cycloastragenol Is a Potent Telomerase Activator in Neuronal Cells: Implications for Depression Management

Neurosignals, 2014
Cycloastragenol (CAG) is an aglycone of astragaloside IV. It was first identified when screening Astragalus membranaceus extracts for active ingredients with antiaging properties. The present study demonstrates that CAG stimulates telomerase activity and
Fanny C.F. Ip, Yu Pong Ng, H.J. An, Ying Dai, Hai Hong Pang, Yue Qing Hu, Allison C. Chin, Calvin B. Harley, Yung Hou Wong, Nancy Y. Ip   +9 more
doaj   +1 more source

Telomerase and Telomeres in Endometrial Cancer

Frontiers in Oncology, 2019
Telomeres at the termini of human chromosomes are shortened with each round of cell division due to the “end replication problem” as well as oxidative stress.
Rafah A. A. Alnafakh, Rafah A. A. Alnafakh, Meera Adishesh, Meera Adishesh, Lucy Button, Lucy Button, Gabriele Saretzki, Dharani K. Hapangama, Dharani K. Hapangama   +8 more
doaj   +1 more source

Human adenovirus DNA polymerase is evolutionarily and functionally associated with human telomerase reverse transcriptase based on in silico molecular characterization that implicate abacavir and zidovudine. [PDF]

Front Bioinform, 2023
Fatoki TH.
europepmc   +1 more source

Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer. [PDF]

Oncol Lett, 2021
Kato T, Nakamori M, Matsumura S, Nakamura M, Ojima T, Fukuhara H, Ino Y, Todo T, Yamaue H.   +8 more
europepmc   +2 more sources

Research Progress on G-Quadruplexes in Human Telomeres and Human Telomerase Reverse Transcriptase (hTERT) Promoter. [PDF]

Oxid Med Cell Longev, 2022
Gu W, Lin Z, Zhao S, Wang G, Shen Z, Liu W, Cai Y, Wang K, Wan CC, Yan T.   +9 more
europepmc   +1 more source

Clinical application of the anti-human telomerase reverse transcriptase (hTERT) antibody (SCD-A7) immunocytochemistry in liquid-based urine cytology: A prospective, single institute study. [PDF]

Cancer Med, 2023
Moon JH, Nikas IP, Moon KC, Kim B, Ryu HS.   +4 more
europepmc   +1 more source

Valproic acid suppresses telomerase activity and downregulates hTERT expression in human colorectal cancer cells [PDF]

Journal of Clinical and Basic Research
Background: Colorectal cancer (CRC) is a leading cause of cancer-related mortality, underscoring the need for novel therapies targeting key drivers of tumor progression.
Mohsen Tatar, Fatemeh Lotfi Asrami, Mehdi Khorami, Fakhraddin Naghibalhossaini   +3 more
doaj  

Human Telomerase Reverse Transcriptase as a Therapeutic Target of Dihydroartemisinin for Esophageal Squamous Cancer. [PDF]

Front Pharmacol, 2021
Li Q, Ma Q, Xu L, Gao C, Yao L, Wen J, Yang M, Cheng J, Zhou X, Zou J, Zhong X, Guo X.   +11 more
europepmc   +1 more source

Implications of risk conferred by 5p15.33 loci genetic variants; human telomerase reverse transcriptase rs2736098 and rs2736100 in predisposition of bladder cancer. [PDF]

Rep Pract Oncol Radiother, 2022
Anwar I, Pandith AA, Mir H, Manzoor U, Amin I, Baba SM, Godha M, Koul AM, Shah ZA, Mansoor S, Wani MS.   +10 more
europepmc   +1 more source