Results 51 to 60 of about 12,358,109 (167)
Total Synthesis of Huperzine R
A total synthesis of huperzine R was accomplished. Intramolecular cycloaddition of a nitrile oxide and reductive cleavage of the resulting isoxazoline induced sequential cleavage of the C–C and C–O bonds to form the characteristic bicyclic lactam core ...
Satoshi Yokoshima +5 more
core +1 more source
Chemical structure of huperzine A.
Chemical structure of huperzine A.
Wenjuan Wang (31234) +10 more
core +1 more source
Protective effect of huperzine A on phenytoin induced cognition impairment: Behavioral and biochemical study [PDF]
205-213Phenytoin, a drug of choice for Epilepsy is also known for its adverse effects. The most common adverse effect due to phenytoin is cognition impairment.
Dubey (Upadhyay), Shagun
core
Total Synthesis of (−)-Huperzine A
The total synthesis of (−)-huperzine A was accomplished in 23 steps from a commercially available anhydride. Our synthetic route features a facile construction of the bicyclo[3.3.1] skeleton equipped with proper functionalities to introduce the remaining
Takahiro Koshiba (1843504) +2 more
core +2 more sources
Huperzine A decreased mitochondrial accumulation of Aβ42.
A. The schematic diagram of the proportion of mitochondria-enriched fraction Aβ42 in total intracellular Aβ42. B. Effect of huperzine A on the level of Aβ42 in different subcellular fractions (N = 4).
Hai Yan Zhang (589189) +7 more
core +1 more source
Correction to Total Synthesis of (−)-Huperzine A
Correction to Total Synthesis of ...
Takahiro Koshiba (1843504) +2 more
core +1 more source
De novo RNA sequencing and transcriptome analysis of Colletotrichum gloeosporioides ES026 reveal genes related to biosynthesis of huperzine A. [PDF]
Huperzine A is important in the treatment of Alzheimer's disease. There are major challenges for the mass production of huperzine A from plants due to the limited number of huperzine-A-producing plants, as well as the low content of huperzine A in these ...
Xiangmei Zhang +10 more
core +1 more source
To study the various processes involved in transcellular transport (TT) of huperzine A alone or in combination with ginkgolide B in Caco-2 and Madin-Darby canine renal (MDCK) cell monolayer.The transepithelial passage was assayed in the apical-to-basolateral (AP to BL) direction and opposite direction (BL to AP) in both cell lines. The determination of
Zhao, Wen-Cui +3 more
openaire +2 more sources
The chemical structure of Huperzine A.
The chemical structure of Huperzine A.
Zhang-Qian Wang (403474) +7 more
core +1 more source
rac-Huperzine A, its rac-7-ethyl-derivative and two regioisomeric analogues have been prepared through synthetic sequences involving the elaboration of the pyridone ring in a late stage, by reaction of an intermediate pyrrolidine enamine with ...
Badia, Albert +8 more
core +1 more source

