Epidermal keratinocytes regulate hyaluronan metabolism via extracellularly secreted hyaluronidase 1 and hyaluronan synthase 3. [PDF]
Abe M +4 more
europepmc +3 more sources
Localisation and endocrine control of hyaluronan synthase (HAS) 2, HAS3 and CD44 expression in sheep granulosa cells [PDF]
A. A. Fouladi-Nashta +65 more
core +3 more sources
Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism. [PDF]
Terabe K +5 more
europepmc +3 more sources
Synaptic Hyaluronan Synthesis and CD44-Mediated Signaling Coordinate Neural Circuit Development
The hyaluronan-based extracellular matrix is expressed throughout nervous system development and is well-known for the formation of perineuronal nets around inhibitory interneurons.
Emily S. Wilson, Karen Litwa
doaj +1 more source
Controlling Hyaluronan Synthase 2 Expression♦ [PDF]
openalex +3 more sources
Mammalian Hyaluronan Synthases [PDF]
AbstractThree mammalian hyaluronan (HA) synthase genes, HAS1, HAS2, and HAS3, have been cloned and expressed, allowing the mechanisms for regulation of HA biosynthesis and function to be studied. The hyaluronan synthase (HAS) isoforms differ in kinetic characteristics and product size.
Naoki, Itano, Koji, Kimata
openaire +2 more sources
Hydrocellular foam dressing promotes wound healing along with increases in hyaluronan synthase 3 and PPARα gene expression in epidermis. [PDF]
BackgroundHydrocellular foam dressing, modern wound dressing, induces moist wound environment and promotes wound healing: however, the regulatory mechanisms responsible for these effects are poorly understood. This study was aimed to reveal the effect of
Takumi Yamane +8 more
doaj +1 more source
Orbital connective tissue expansion is a hallmark of Graves’ orbitopathy (GO). In moderate-to-severe active GO, glucocorticoids (GC) are the first line of treatment.
Erika Galgoczi +10 more
doaj +1 more source
Mycobacteria exploit host hyaluronan for efficient extracellular replication. [PDF]
In spite of the importance of hyaluronan in host protection against infectious organisms in the alveolar spaces, its role in mycobacterial infection is unknown.
Yukio Hirayama +11 more
doaj +1 more source

